A revolução da Gabriela: o ano de 1977 em Portugal

Este trabalho apresenta os contextos da visionação, em 1977, da telenovela brasileira Gabriela, Cravo e Canela. Justifica-se a escolha do Corpus – dois diários (Diário de Notícias, Diário de Lisboa) e dois semanários (Expresso e O Jornal) explicitando-se as metodologias utilizadas na análise de imprensa. Faz-se o levantamento da agenda da telenovela Gabriela, Cravo e Canela nos quatro jornais seleccionados, confrontando-a com outra agenda, mais lata, da expansão e divulgação da indústria cultural brasileira em Portugal. Considera-se que o êxito desta telenovela antecipa a emergência de uma nova sociedade e estilos de vida, bem como uma outra imagem da mulher, centrados em novos valores, no consumo e nos media.This work describes the reception of the Brazilian telenovela Gabriela, Cravo e Canela in the year of 1977 in Portugal. The corpus is composed of two daily newspapers (Diário de Notícias, Diário de Lisboa) and two weekly papers (Expresso e O Jornal); The methods of analisys are presented. Afterwards the Agenda of the telenovela Gabriela... is identified in these newspapers and compared with the Agenda of Brasilian Cultural Industry in Portugal. The conclusion aims at a relation between the exhibition of the telenovela and the rise of a new society with new women’s models and life styles

Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry

Background: Previous studies suggested potential ethnic differences in the management and outcomes of atrial fibrillation (AF). We aim to analyse oral anticoagulant (OAC) prescription, discontinuation, and risk of adverse outcomes in Asian patients with AF, using data from a global prospective cohort study. Methods: From the GLORIA-AF Registry Phase II-III (November 2011-December 2014 for Phase II, and January 2014-December 2016 for Phase III), we analysed patients according to their self-reported ethnicity (Asian vs. non-Asian), as well as according to Asian subgroups (Chinese, Japanese, Korean and other Asian). Logistic regression was used to analyse OAC prescription, while the risk of OAC discontinuation and adverse outcomes were analysed through Cox-regression model. Our primary outcome was the composite of all-cause death and major adverse cardiovascular events (MACE). The original studies were registered with ClinicalTrials.gov, NCT01468701, NCT01671007, and NCT01937377. Findings: 34,421 patients were included (70.0 ± 10.5 years, 45.1% females, 6900 (20.0%) Asian: 3829 (55.5%) Chinese, 814 (11.8%) Japanese, 1964 (28.5%) Korean and 293 (4.2%) other Asian). Most of the Asian patients were recruited in Asia (n = 6701, 97.1%), while non-Asian patients were mainly recruited in Europe (n = 15,449, 56.1%) and North America (n = 8378, 30.4%). Compared to non-Asian individuals, prescription of OAC and non-vitamin K antagonist oral anticoagulant (NOAC) was lower in Asian patients (Odds Ratio [OR] and 95% Confidence Intervals (CI): 0.23 [0.22-0.25] and 0.66 [0.61-0.71], respectively), but higher in the Japanese subgroup. Asian ethnicity was also associated with higher risk of OAC discontinuation (Hazard Ratio [HR] and [95% CI]: 1.79 [1.67-1.92]), and lower risk of the primary composite outcome (HR [95% CI]: 0.86 [0.76-0.96]). Among the exploratory secondary outcomes, Asian ethnicity was associated with higher risks of thromboembolism and intracranial haemorrhage, and lower risk of major bleeding. Interpretation: Our results showed that Asian patients with AF showed suboptimal thromboembolic risk management and a specific risk profile of adverse outcomes; these differences may also reflect differences in country-specific factors. Ensuring integrated and appropriate treatment of these patients is crucial to improve their prognosis. Funding: The GLORIA-AF Registry was funded by Boehringer Ingelheim GmbH

Correction to: Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry

International audienceIn this article, the name of the GLORIA-AF investigator Anastasios Kollias was given incorrectly as Athanasios Kollias in the Acknowledgements. The original article has been corrected