A Classification of Uncertainty for Early Product and System Design

Complex systems and products evolve over years to meet new requirements, while applying tried and tested technology. To maximise the reuse of components through the life span, companies need to plan for the changes that they can anticipate, and facilitate accommodation of such changes in the original architecture and design of the system. Methods such as design for flexibility or design for changeability promote incorporation of future uncertain outcomes into system and product design in one way or another. However, the degree to which future product changes can be planned depends on the uncertainties that the system, product or product family is subject to. A deeper understanding of these uncertainties is the focus of this paper. The paper first provides a brief literature survey, and discusses the sources and nature of uncertainty. This is followed by a classification of the types of uncertainties that are often encountered and that should be considered, as well as methods and techniques for modelling these uncertainties for incorporation in system design. The paper also provides examples of uncertainties for a variety of systems and products throughout and concludes with an uncertainty checklist for system architects and product designers

Assessing the Medical Emergency Preparedness of Dental Faculty, Residents, and Practicing Periodontists: An Exploratory Study

With the increased number of elderly and medically compromised individuals receiving dental care and the presence of systemic comorbidities and associated treatment modalities in this patient population, it is imperative that dentists be prepared to manage a variety of medical emergencies. The aim of this study was to assess the knowledge of and preparedness to manage common medical emergencies of cohorts of practicing periodontists, specialty residents, and faculty members, both for comparative purposes and as an aid to refining a dental school’s standardized case scenarios. The study, conducted in 2017, was designed for four groups of randomly selected participants with at least 20 in each group; the actual number of voluntary participants was 28 private practice periodontists, 22 residents in specialty programs, 21 specialist faculty members, and 24 general practice faculty members. Participants were asked to evaluate ten clinical emergency cases and identify the diagnosis and indicated intervention for each. Groups were also evaluated for differences among correct responses for each case. Overall, there were no statistically significant differences for number of correct diagnoses or interventions among the four groups. However, several cases had varying degrees of incorrect diagnoses and management across all groups. Participants who had recently graduated or were still in school were able to treat cases appropriately more often than the other participants. Further refinement of cases to assess provider preparedness to correctly diagnose and manage medical emergencies is needed, specifically establishing case-specific features and addressing areas of potential confusion before the cases are used for educational purposes

A textbook example of ram-pressure stripping in the Hydra A/A780 cluster

In the current epoch, one of the main mechanisms driving the growth of galaxy clusters is the continuous accretion of group-scale halos. In this process, the ram pressure applied by the hot intracluster medium on the gas content of the infalling group is responsible for stripping the gas from its dark-matter halo, which gradually leads to the virialization of the infalling gas in the potential well of the main cluster. Using deep wide-field observations of the poor cluster Hydra A/A780 with XMM-Newton and Suzaku, we report the discovery of an infalling galaxy group 1.1 Mpc south of the cluster core. The presence of a substructure is confirmed by a dynamical study of the galaxies in this region. A wake of stripped gas is trailing behind the group over a projected scale of 760 kpc. The temperature of the gas along the wake is constant at kT ~ 1.3 keV, which is about a factor of two less than the temperature of the surrounding plasma. We observe a cold front pointing westwards compared to the peak of the group, which indicates that the group is currently not moving in the direction of the main cluster, but is moving along an almost circular orbit. The overall morphology of the group bears remarkable similarities with high-resolution numerical simulations of such structures, which greatly strengthens our understanding of the ram-pressure stripping process

Sedimentation of colloidal plate-sphere mixtures and inference of particle characteristics from stacking sequences

We investigate theoretically the effect of gravity on a plate-sphere colloidal mixture by means of an Onsager-like density functional to describe the bulk, and sedimentation path theory to incorporate gravity. We calculate the stacking diagram of the mixture for two sets of buoyant masses and different values of the sample height. Several stacking sequences appear due to the intricate interplay between gravity, the sample height, and bulk phase separation. These include the experimentally observed floating nematic sequence, which consists of a nematic layer sandwiched between two isotropic layers. The values of the thicknesses of the layers in a complex stacking sequence can be used to obtain microscopic information of the mixture. Using the thicknesses of the layers in the floating nematic sequence we are able to infer the values of the buoyant masses from the colloidal concentrations and vice versa. We also predict new phenomena that can be experimentally tested, such as a nontrivial evolution of the stacking sequence by increasing the sample height in which new layers appear either at the top or at the bottom of the sample

Sedimentation path theory for mass-polydisperse colloidal systems

Both polydispersity and the presence of a gravitational field are inherent to essentially any colloidal experiment. While several theoretical works have focused on the effect of polydispersity on the bulk phase behavior of a colloidal system, little is known about the effect of a gravitational field on a polydisperse colloidal suspension. We extend here sedimentation path theory to study sedimentation of a mass-polydisperse colloidal system: the particles possess different buoyant masses but they are otherwise identical. The model helps to understand the interplay between gravity and polydispersity on sedimentation experiments. Since the theory can be applied to any parent distribution of buoyant masses, it can be also used to study sedimentation of monodisperse colloidal systems. We find that mass-polydispersity has a strong influence in colloidal systems near density matching for which the bare density of the colloidal particles equals the solvent density. To illustrate the theory, we study crystallization in sedimentation-diffusion-equilibrium of a suspension of mass-polydisperse hard spheres

XMM-Newton and INTEGRAL analysis of the Ophiuchus cluster of galaxies

We investigated the non-thermal hard X-ray emission in the Ophiuchus cluster of galaxies. Our aim was to characterise the physical properties of the non-thermal component and its interaction with the cosmic microwave background. We performed spatially resolved spectroscopy and imaging using XMM-Newton data to model the thermal emission. Combining this with INTEGRAL ISGRI data, we modeled the 0.6-140 keV band total emission in the central 7 arcmin region. The models that best describe both PN and ISGRI data contain a power-law component with a photon index in a range 2.2-2.5. This component produces ~10% of the total flux in the 1-10 keV band. The pressure of the non-thermal electrons is ~1% of that of the thermal electrons. Our results support the scenario whereby a relativistic electron population, which produces the recently detected radio mini-halo in Ophiuchus, also produces the hard X-rays via inverse compton scattering of the CMB photons. The best-fit models imply a differential momentum spectrum of the relativistic electrons with a slope of 3.4-4.0 and a magnetic field strength B=0.05-0.15 microG. The lack of evidence for a recent major merger in the Ophiuchus center allows the possibility that the relativistic electrons are produced by turbulence or hadronic collisions.Comment: Accepted for publication in Astronomy and Astrophysics, v2 includes some text improvement

X-ray observations of PKS 0745-191 at the virial radius: Are we there yet?

We wish to reassess the properties of the ICM at large radii in the galaxy cluster PKS 0745-191 in light of the recent Suzaku measurements. We analyze an archival 10.5 ksec ROSAT/PSPC observation to extract the surface-brightness profile of PKS 0745-191 and infer the deprojected density profile. We then compare the ROSAT surface-brightness profile with the Suzaku result. We perform a mass analysis combining the ROSAT density profile and the published temperature profiles from different instruments. We find that the ROSAT surface-brightness profile is statistically inconsistent (7.7 sigma) with the Suzaku result around and beyond the value of r200 estimated by Suzaku. We argue that, thanks to its large field of view and low background, ROSAT/PSPC is to the present day the most sensitive instrument to low surface-brightness X-ray emission in the 0.4-2.0 keV band. We also note that the Suzaku temperature and mass profiles are at odds with the results from at least two other satellites (XMM-Newton and Swift). The difference in surface brightness between ROSAT and Suzaku is most likely explained by the existence of additional foreground components at the low Galactic latitude of the source, which were not taken into account in the Suzaku background modeling. In light of our mass analysis, we conclude that any estimate of the fraction of the virial radius reached by X-ray measures is affected by systematic errors of the order of 25%. As a result, the properties of the ICM at the virial radius are still uncertain, and the Suzaku results should be considered with caution.Comment: 6 pages, 5 figures, accepted for publication in A&

Sustainable entrepreneurial process : from idea generation to impact measurement

In order to promote sustainable entrepreneurship, it is necessary to understand the sustainable entrepreneurial process. To address this gap in the literature, this study aims to investigate how entrepreneurs generate ideas, as well as recognize, develop, and exploit opportunities in the context of sustainable development. A case study was carried out with eleven organizations in six different countries, from different sectors, including not-for-profit and for-profit businesses. The findings address a series of mechanisms that occur prior to the process of generating an idea and are relevant to the positive impact of these businesses on society. Entrepreneurs’ previous experiences and skills, as well as the knowledge of similar initiatives, strongly relate to motivation and idea generation. In the analyzed cases, prior experience seemed to be related to a sensitivity towards a social or environmental problem. Previous experience in entrepreneurship was not determinant. The quality of the initial idea was relevant, once little changes occurred throughout the entire process. In most situations both dimensions of sustainability were integrated at the same time and before venture launch. Despite this, the focus of the entrepreneurs was on only one dimension. The inclusion of positive impact measurement on society, as part of the sustainable entrepreneurial process model, is another relevant finding. First, it is necessary to differentiate the sustainable entrepreneur from the regular and the social entrepreneur. Secondly, in some situations, the dimensions of sustainability are not integrated at the same time and before venture launch, and therefore considering that the process is finished in the phase of venture launch can lead to misclassifications. The results also led to the recognition of triggers that can stimulate sustainable entrepreneurship, such as educational practices more aligned with sustainability problems faced by local communities, stronger dissemination of successful business cases related to sustainability in other countries and contexts, integration between universities and businesses, and the inclusion of practice-based learning in curricula. A contribution to the literature was achieved by providing a systemic perspective on sustainable entrepreneurial process. This study also contributes by presenting empirical evidence of the phenomenon of sustainable entrepreneurship. The holistic knowledge of this process provides new information that supports academics, policy makers, government, and individuals with a more appropriate understanding of the conditions that help to stimulate new business activities dealing with economic, social, and environmental problems faced in society, helping to achieve the United Nations Sustainable Development Goals