1,761 research outputs found
Anisotropic Aerogels for Studying Superfluid He
It may be possible to stabilize new superfluid phases of He with
anisotropic silica aerogels. We discuss two methods that introduce anisotropy
in the aerogel on length scales relevant to superfluid He. First,
anisotropy can be induced with uniaxial strain. A second method generates
anisotropy during the growth and drying stages. We have grown cylindrical
98% aerogels with anisotropy indicated by preferential radial shrinkage
after supercritical drying and find that this shrinkage correlates with small
angle x-ray scattering (SAXS). The growth-induced anisotropy was found to be
out of phase relative to that induced by strain. This has
implications for the possible stabilization of superfluid phases with specific
symmetry.Comment: 6 pages, 4 figures, submitted to Quantum Fluids and Solids (QFS)
conference 200
Using cardiovascular cells from human pluripotent stem cells for COVID-19 research: the heart fails
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the coronavirus disease (COVID-19) outbreak that became a pandemic in 2020, causing more than 30 million infections and 1 million deaths to date. As the scientific community has looked for vaccines and drugs to treat or eliminate the virus, unexpected features of the disease have emerged. Apart from respiratory complications, cardiovascular disease has emerged as a major indicator of poor prognosis in COVID-19. It has therefore become of utmost importance to understand how SARS-CoV-2 damages the heart. Human pluripotent stem cell (hPSC) cardiovascular derivatives were rapidly recognized as an invaluable tool to address this, not least because one of the major receptors for the virus is not recognized by SARS-CoV-2 in mice. Here, we outline how hPSC-derived cardiovascular cells have been utilized to study COVID-19, and their potential for further understanding the cardiac pathology and in therapeutic development.Stem cells & developmental biolog
A fly in the buttermilk: Descriptions of university life by successful Black undergraduate students at a predominately white southeastern university
Although many predominantly white universities exert great effort to recruit minority students, statistics regarding retention and graduation for these students are disturbing. Previous research indicates that academic concerns are not paramount in the attrition of minority students, suggesting that greater attention must be given educational experiences of black students over and above academic matters. Using in-depth phenomenological interviewing, 11 graduating seniors from diverse majors were asked to describe salient incidents of their university experience. These interviews were transcribed verbatim and subjected to hermeneutic interpretation by an interdisciplinary research group. Dominant in student descriptions of their experiences were five themes: (1) It happens every day : Unfairness/Sabotage/Condescension; (2) You have to initiate the conversation ; (3) They seem the same; I\u27m the one who\u27s different ; (4) I have to prove I\u27m worthy to be here ; and (5) Sometimes I\u27m not even here/Sometimes I have to represent every black student : Invisibility and Supervisibility
Gravitational-wave astronomy: the high-frequency window
This contribution is divided in two parts. The first part provides a
text-book level introduction to gravitational radiation. The key concepts
required for a discussion of gravitational-wave physics are introduced. In
particular, the quadrupole formula is applied to the anticipated
``bread-and-butter'' source for detectors like LIGO, GEO600, EGO and TAMA300:
inspiralling compact binaries. The second part provides a brief review of high
frequency gravitational waves. In the frequency range above (say) 100Hz,
gravitational collapse, rotational instabilities and oscillations of the
remnant compact objects are potentially important sources of gravitational
waves. Significant and unique information concerning the various stages of
collapse, the evolution of protoneutron stars and the details of the
supranuclear equation of state of such objects can be drawn from careful study
of the gravitational-wave signal. As the amount of exciting physics one may be
able to study via the detections of gravitational waves from these sources is
truly inspiring, there is strong motivation for the development of future
generations of ground based detectors sensitive in the range from hundreds of
Hz to several kHz.Comment: 21 pages, 5 figures, Lectures presented at the 2nd Aegean Summer
School on the Early Universe, Syros, Greece, September 200
Superradiation from Crystals of High-Spin Molecular Nanomagnets
Phenomenological theory of superradiation from crystals of high-spin
molecules is suggested. We show that radiation friction can cause a
superradiation pulse and investigate the role of magnetic anisotropy, external
magnetic field and dipole-dipole interactions. Depending on the contribution of
all these factors at low temperature, several regimes of magnetization of
crystal sample are described. Very fast switch of magnetization's direction for
some sets of parameters is predicted.Comment: 10 pages, 3 figure
The UNC-Wisconsin rhesus macaque neurodevelopment database: A structural MRI and DTI database of early postnatal development
Rhesus macaques are commonly used as a translational animal model in neuroimaging and neurodevelopmental research. In this report, we present longitudinal data from both structural and diffusion MRI images generated on a cohort of 34 typically developing monkeys from 2 weeks to 36 months of age. All images have been manually skull stripped and are being made freely available via an online repository for use by the research community
On the dual structure of the auditory brainstem response in dogs
Objective: To use the over-complete discrete wavelet transform (OCDWT) to further examine the dual structure of auditory brainstem response (ABR) in the dog. Methods: ABR waveforms recorded from 20 adult dogs at supra-threshold (90 and 70 dBnHL) and threshold (0-15 dBSL) levels were decomposed using a six level OCDWT and reconstructed at individual scales (frequency ranges) A6 (0-391 Hz), D6 (391-781 Hz), and D5 (781-1563 Hz). Results: At supra-threshold stimulus levels, the A6 scale (0-391 Hz) showed a large amplitude waveform with its prominent wave corresponding in latency with ABR waves II/III; the D6 scale (391-781 Hz) showed a small amplitude waveform with its first four waves corresponding in latency to ABR waves I, II/III, V, and VI; and the D5 scale (781-1563 Hz) showed a large amplitude, multiple peaked waveform with its first six waves corresponding in latency to ABR waves I, II, III, IV, V, and VI. At threshold stimulus levels (0-15 dBSL), the A6 scale (0-391 Hz) continued to show a relatively large amplitude waveform, but both the D6 and D5 scales (391781 and 781-1563 Hz, respectively) now showed relatively small amplitude waveforms. Conclusions: A dual structure exists within the ABR of the dog, but its relative structure changes with stimulus level. Significance: The ABR in the dog differs from that in the human both in the relative contributions made by its different frequency components, and the way these components change with stimulus level. (c) 2006 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved
CMB polarization from secondary vector and tensor modes
We consider a novel contribution to the polarization of the Cosmic Microwave
Background induced by vector and tensor modes generated by the non-linear
evolution of primordial scalar perturbations. Our calculation is based on
relativistic second-order perturbation theory and allows to estimate the
effects of these secondary modes on the polarization angular power-spectra. We
show that a non-vanishing B-mode polarization unavoidably arises from pure
scalar initial perturbations, thus limiting our ability to detect the signature
of primordial gravitational waves generated during inflation. This secondary
effect dominates over that of primordial tensors for an inflationary
tensor-to-scalar ratio . The magnitude of the effect is smaller than
the contamination produced by the conversion of polarization of type E into
type B, by weak gravitational lensing. However the lensing signal can be
cleaned, making the secondary modes discussed here the actual background
limiting the detection of small amplitude primordial gravitational waves.Comment: 14 pages, 3 figures, minor changes matching the version to be
published in Phys. Rev.
A Supersymmetric SO(10) Model with Inflation and Cosmic Strings
We have built a supersymmetric SO(10) model consistent with cosmological
observations. The model gives rise to a false vacuum hybrid inflationary
scenario which solves the monopole problem. We argue that this type of
inflationary scenario is generic in supersymmetric SO(10) model, and arises
naturally from the theory. Neither any external field nor any external symmetry
has to be added. It can just be a consequence of the theory. In our specific
model, at the end of inflation, cosmic strings form. The properties of the
strings are presented. The cosmic background radiation anisotropies induced by
the inflationary perturbations and the cosmic strings are estimated. The model
produces a stable lightest superparticle and a very light left-handed neutrino
which may serve as the cold and hot dark matter. The properties of a mixed
cosmic string-inflationary large scale structure formation scenario are
discussed.Comment: 32 pages, uses RevTex. Misprint in a referenc
Structure of the icosahedral Ti-Zr-Ni quasicrystal
The atomic structure of the icosahedral Ti-Zr-Ni quasicrystal is determined
by invoking similarities to periodic crystalline phases, diffraction data and
the results from ab initio calculations. The structure is modeled by
decorations of the canonical cell tiling geometry. The initial decoration model
is based on the structure of the Frank-Kasper phase W-TiZrNi, the 1/1
approximant structure of the quasicrystal. The decoration model is optimized
using a new method of structural analysis combining a least-squares refinement
of diffraction data with results from ab initio calculations. The resulting
structural model of icosahedral Ti-Zr-Ni is interpreted as a simple decoration
rule and structural details are discussed.Comment: 12 pages, 8 figure
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