Automatic Cephalometric Analysis

Abstract Objective: To describe the techniques used for automatic landmarking of cephalograms, highlighting the strengths and weaknesses of each one and reviewing the percentage of success in locating each cephalometric point. Materials and Methods: The literature survey was performed by searching the Medline, the Institute of Electrical and Electronics Engineers, and the ISI Web of Science Citation Index databases. The survey covered the period from January 1966 to August 2006. Abstracts that appeared to fulfill the initial selection criteria were selected by consensus. The original articles were then retrieved. Their references were also hand-searched for possible missing articles. The search strategy resulted in 118 articles of which eight met the inclusion criteria. Many articles were rejected for different reasons; among these, the most frequent was that results of accuracy for automatic landmark recognition were presented as a percentage of success. Results: A marked difference in results was found between the included studies consisting of heterogeneity in the performance of techniques to detect the same landmark. All in all, hybrid approaches detected cephalometric points with a higher accuracy in contrast to the results for the same points obtained by the model-based, image filtering plus knowledge-based landmark search and "soft-computing" approaches. Conclusions: The systems described in the literature are not accurate enough to allow their use for clinical purposes. Errors in landmark detection were greater than those expected with manual tracing and, therefore, the scientific evidence supporting the use of automatic landmarking is low

A baseline on continual learning methods for video action recognition

Continual learning has recently attracted attention from the research community, as it aims to solve long-standing limitations of classic supervisedly-trained models. However, most research on this subject has tackled continual learning in simple image classification scenarios. In this paper, we present a benchmark of state-of-the-art continual learning methods on video action recognition. Besides the increased complexity due to the temporal dimension, the video setting imposes stronger requirements on computing resources for top-performing rehearsal methods. To counteract the increased memory requirements, we present two method-agnostic variants for rehearsal methods, exploiting measures of either model confidence or data information to select memorable samples. Our experiments show that, as expected from the literature, rehearsal methods outperform other approaches; moreover, the proposed memory-efficient variants are shown to be effective at retaining a certain level of performance with a smaller buffer size

Género, salud mental y terapia ocupacional: algunas reflexiones sobre la influencia de la historia de las mujeres y la perspectiva de género en nuestras prácticas

This work presents some reflections on the issue of gender in mental health and occupational therapy practices of two historical situations showing two different but related practices: on one hand aspects linked to the performance of women in the public domain and on the other hand, stand out the implication of gender relations in such action. This paper intent to analyze the impact of those representations of gender in the field of mental health and its relationship with the current practices of occupational therapy. It presents the constituent elements of the concept of gender to identify care logic aimed at responding to the issue of mental health, reproducing the structure of power and domination of gender relations. Intents to include gender mainstreaming in occupational therapy practices wherever instrument interventions, strategies, or devices in health, bearing in mind that the tension between the practice of occupational therapy and the gender system constraints, is always in relation with the particular process of subjectivation of each of the subjects with which intervenes.Se presentan algunas reflexiones sobre la problemática de género en las prácticas de salud mental y de Terapia Ocupacional a partir de dos situaciones históricas que muestran, por un lado aspectos vinculados con la actuación de las mujeres en el ámbito público, y por otro destacan la implicancia de las relaciones de género en dichas actuaciones. El objetivo es analizar el impacto de las representaciones de género en el campo de la salud mental y su relación con las prácticas actuales de la Terapia Ocupacional. Se presentan los elementos constitutivos del concepto de género para identificar las lógicas asistenciales destinadas a dar respuesta a la problemática de salud mental, que reproducen el entramado de poder y dominación característico de las relaciones de género. Se propone incluir la perspectiva de género en las prácticas de la Terapia Ocupacional cada vez que se instrumenten intervenciones, estrategias o dispositivos en salud; teniendo presente que la tensión entre la práctica de la Terapia Ocupacional y los condicionamientos del sistema de género, está siempre en relación al proceso particular de subjetivación de cada uno de los sujetos con los que se interviene

ASF1 Proteins are Involved in UV-induced DNA Damage Repair and are Cell Cycle Regulated by E2F Transcription Factors in Arabidopsis thaliana

ASF1 is a key histone H3/H4 chaperone that participates in a variety of DNA and chromatin-related processes, including DNA repair, where chromatin assembly and disassembly is of primaryrelevance. Information concerning the role of ASF1 proteins in post-UV response in higher plants is currently limited. In Arabidopsis thaliana, an initial analysis of in vivo localization of ASF1A andASF1B indicates that both proteins are mainly expressed in proliferative tissues. In silico promoteranalysis identified ASF1A and ASF1B as potential targets of E2F transcription factors. Theseobservations were experimentally validated, both in vitro by electrophoretic mobility shift assays, and in vivo by chromatin immunoprecipitation assays and expression analysis using transgenic plants with altered levels of different E2F transcription factors. These data suggest that ASF1A and ASF1B are regulated during cell cycle progression through E2F transcription factors. In addition, we found that ASF1A and ASF1B are associated with the UV-B induced DNA damage response in A. thaliana. Transcript levels of ASF1A and ASF1B were increased following a UV-B-treatment. Consistent with a potential role in ultraviolet-B (UV-B) response, RNAi silenced plants of both genes showed increased sensitivity to UV-B compared to wild type plants. Finally, by coimmunoprecipitation analysis, we found that ASF1 physically interacts with N-terminal acetylated histones H3 and H4, and with acetyltransferases of the HAM subfamily, which are known to be involved in cell cycle control and DNA repair, among other functions. Together, here we provide evidence that ASF1A and ASF1B are regulated by cell cycle progression and are involved in DNA repair after UV-B irradiation.Fil: Lario, Luciana Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Centro de Estudios Fotosintéticos y Bioquímicos (i); ArgentinaFil: Gutierrez, Crisanto. Universidad Autónoma de Madrid; EspañaFil: Ramirez Parra, Elena. Universidad Politecnica de Madrid; EspañaFil: Spampinato, Claudia Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Centro de Estudios Fotosintéticos y Bioquímicos (i); ArgentinaFil: Casati, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Centro de Estudios Fotosintéticos y Bioquímicos (i); Argentin

Different patterns of cortical excitability in major depression and vascular depression: a transcranial magnetic stimulation study

BACKGROUND: Clinical and functional studies consider major depression (MD) and vascular depression (VD) as different neurobiological processes. Hypoexcitability of the left frontal cortex to transcranial magnetic stimulation (TMS) is frequently reported in MD, whereas little is known about the effects of TMS in VD. Thus, we aimed to assess and compare motor cortex excitability in patients with VD and MD. METHODS: Eleven VD patients, 11 recurrent drug-resistant MD patients, and 11 healthy controls underwent clinical, neuropsychological and neuroimaging evaluations in addition to bilateral resting motor threshold, cortical silent period, and paired-pulse TMS curves of intracortical excitability. All patients continued on psychotropic drugs, which were unchanged throughout the study. RESULTS: Scores on one of the tests evaluating frontal lobe abilities (Stroop Color-Word interference test) were worse in patients compared with controls. The resting motor threshold in patients with MD was significantly higher in the left hemisphere compared with the right (p < 0.05), and compared with the VD patients and controls. The cortical silent period was bilaterally prolonged in MD patients compared with VD patients and controls, with a statistically significant difference in the left hemisphere (p < 0.01). No differences were observed in the paired-pulse curves between patients and controls. CONCLUSIONS: This study showed distinctive patterns of motor cortex excitability between late-onset depression with subcortical vascular disease and early-onset recurrent drug resistant MD. The data provide a TMS model of the different processes underlying VD and MD. Additionally, our results support the “Vascular depression hypothesis” at the neurophysiological level, and confirm the inter-hemispheric asymmetry to TMS in patients with MD. We were unable to support previous findings of impaired intracortical inhibitory mechanisms to TMS in patients with MD, although a drug-induced effect on our results cannot be excluded. This study may aid the understanding of the pathogenetic differences underlying the clinical spectrum of depressive disorders