History-based action selection bias in posterior parietal cortex.

Making decisions based on choice-outcome history is a crucial, adaptive ability in life. However, the neural circuit mechanisms underlying history-dependent decision-making are poorly understood. In particular, history-related signals have been found in many brain areas during various decision-making tasks, but the causal involvement of these signals in guiding behavior is unclear. Here we addressed this issue utilizing behavioral modeling, two-photon calcium imaging, and optogenetic inactivation in mice. We report that a subset of neurons in the posterior parietal cortex (PPC) closely reflect the choice-outcome history and history-dependent decision biases, and PPC inactivation diminishes the history dependency of choice. Specifically, many PPC neurons show history- and bias-tuning during the inter-trial intervals (ITI), and history dependency of choice is affected by PPC inactivation during ITI and not during trial. These results indicate that PPC is a critical region mediating the subjective use of history in biasing action selection

Selection of high-z supernovae candidates

Deep, ground based, optical wide-field supernova searches are capable of detecting a large number of supernovae over a broad redshift range up to z~1.5. While it is practically unfeasible to obtain spectroscopic redshifts of all the supernova candidates right after the discovery, we show that the magnitudes and colors of the host galaxies, as well as the supernovae, can be used to select high-z supernova candidates, for subsequent spectroscopic and photometric follow-up. Using Monte-Carlo simulations we construct criteria for selecting galaxies in well-defined redshift bands. For example, with a selection criteria using B-R and R-I colors we are able to pick out potential host galaxies for which z>0.85 with 80% confidence level and with a selection efficiency of 64-86%. The method was successfully tested using real observations from the HDF. Similarly, we show that that the magnitude and colors of the supernova discovery data can be used to constrain the redshift. With a set of cuts based on V-R and R-I in a search to m_I~25, supernovae at z~1 can be selected in a redshift interval sigma_z <0.15.Comment: 33 pages, 13 figures, accepted for publication in PASP (March 2002 issue

Lensing magnification of supernovae in the GOODS-fields

Gravitational lensing of high-redshift supernovae is potentially an important source of uncertainty when deriving cosmological parameters from the measured brightness of Type Ia supernovae, especially in deep surveys with scarce statistics. Photometric and spectroscopic measurements of foreground galaxies along the lines-of-sight of 33 supernovae discovered with the Hubble Space Telescope, both core-collapse and Type Ia, are used to model the magnification probability distributions of the sources. Modelling galaxy halos with SIS or NFW-profiles and using M/L scaling laws provided by the Faber-Jackson and Tully-Fisher relations, we find clear evidence for supernovae with lensing (de)magnification. However, the magnification distribution of the Type Ia supernovae used to determine cosmological distances matches very well the expectations for an unbiased sample, i.e.their mean magnification factor is consistent with unity. Our results show that the lensing distortions of the supernova brightness can be well understood for the GOODS sample and that correcting for this effect has a negligible impact on the derived cosmological parameters.Comment: 22 pages, 9 figures, accepted for publication by Ap

The Deepest Supernova Search is Realized in the Hubble Ultra Deep Field Survey

The Hubble Ultra Deep Field Survey has not only provided the deepest optical and near infrared views of universe, but has enabled a search for the most distant supernovae to z~2.2. We have found four supernovae by searching spans of integrations of the Ultra Deep Field and the Ultra Deep Field Parallels taken with the Hubble Space Telescope paired with the Advanced Camera for Surveys and the Near Infrared Multi Object Spectrometer. Interestingly, none of these supernovae were at z>1.4, despite the substantially increased sensitivity per unit area to such objects over the Great Observatories Origins Deep Survey. We present the optical photometric data for the four supernovae. We also show that the low frequency of Type Ia supernovae observed at z>1.4 is statistically consistent with current estimates of the global star formation history combined with the non-trivial assembly time of SN Ia progenitors.Comment: 24 pages (6 figures), submitted to the Astronomical Journa

Corrections for gravitational lensing of supernovae: better than average?

We investigate the possibility of correcting for the magnification due to gravitational lensing of standard candle sources, such as Type Ia supernovae. Our method uses the observed properties of the foreground galaxies along the lines-of-sight to each source and the accuracy of the lensing correction depends on the quality and depth of these observations as well as the uncertainties in translating the observed luminosities to the matter distribution in the lensing galaxies. The current work is limited to cases where the matter density is dominated by the individual galaxy halos. However, it is straightforward to generalize the method to include also gravitational lensing from cluster scale halos. We show that the dispersion due to lensing for a standard candle source at z=1.5 can be reduced from about 7% to ~< 3%, i.e. the magnification correction is useful in reducing the scatter in the Type Ia Hubble diagram, especially at high redshifts where the required long exposure times makes it hard to reach large statistics and the dispersion due to lensing becomes comparable to the intrinsic Type Ia scatter.Comment: Matches accepted version, includes clarifications and additional issues. 28 pages, 7 figures, accepted for publication in Ap

Supernovae Rates: A Cosmic History

We discuss the cosmic history of supernovae on the basis of various assumptions and recent data on the star formation history. We show that supernova rates as a function of redshift can be used to place significant constraints on progenitor models, on the star formation history, and on the importance of dust obscuration. We demonstrate that it is unlikely that the current observational indications for the existence of a cosmological constant are merely an artifact of the dominance of different progenitor classes at different redshift intervals.Comment: Accepted for publication in The Astrophysical Journa

Disengagement of motor cortex from movement control during long-term learning.

Motor learning involves reorganization of the primary motor cortex (M1). However, it remains unclear how the involvement of M1 in movement control changes during long-term learning. To address this, we trained mice in a forelimb-based motor task over months and performed optogenetic inactivation and two-photon calcium imaging in M1 during the long-term training. We found that M1 inactivation impaired the forelimb movements in the early and middle stages, but not in the late stage, indicating that the movements that initially required M1 became independent of M1. As previously shown, M1 population activity became more consistent across trials from the early to middle stage while task performance rapidly improved. However, from the middle to late stage, M1 population activity became again variable despite consistent expert behaviors. This later decline in activity consistency suggests dissociation between M1 and movements. These findings suggest that long-term motor learning can disengage M1 from movement control

Detecting z > 2 Type IIn Supernovae

Type IIn supernovae (SNe IIn) dominate the brightest supernova events in observed FUV flux (~1200-2000A). We show that multi-band, multi-epoch optical surveys complete to m_r = 27 can detect the FUV emission of ~25 z > 2 SNe IIn deg^-2 yr^-1 rest-frame (~10 SNe IIn deg^-2 yr^-1 observed-frame) to 4 sigma using a technique monitoring color-selected galaxies. Moreover, the strength and evolution of the bright emission lines observed in low redshift SNe IIn imply that the Ly-a emission features in ~70% of z > 2 SNe IIn are above 8m-class telescope spectroscopic thresholds for ~2 yr rest-frame. As a result, existing facilities have the capability to both photometrically detect and spectroscopically confirm z > 2 SNe IIn and pave the way for efficient searches by future 8m-class survey and 30m-class telescopes. The method presented here uses the sensitivities and wide-field capabilities of current optical instruments and exploits (1) the efficiency of z > 2 galaxy color-selection techniques, (2) the intrinsic brightness distribution ( = -19.0 +/-0.9) and blue profile of SNe IIn continua, (3) the presence of extremely bright, long-lived emission features, and (4) the potential to detect blueshifted SNe Ly-a emission shortward of host galaxy Ly-a features.Comment: 26 pages (pre-print), 6 figures, accepted Ap