29 research outputs found
Insetos em presépios e as "formigas vestidas" de Jules Martin (1832-1906): uma curiosa manufatura paulistana do final do século XIX
Encontrados no Brasil desde os primórdios da colonização portuguesa, os presépios logo tiveram de adaptar-se à realidade local, circunstância muito propÃcia ao aparecimento de concepções heterodoxas e ao emprego de elementos exóticos da fauna e flora de cada região. Como registros envolvendo insetos são muito pouco comuns, chama a atenção que fêmeas de saúva, Atta sp. (Hymenoptera, Formicidae), tenham sido aproveitadas na composição de presépios no estado de São Paulo. Tendo subsistido pelo menos até a década 1960, os "presépios de formigas" existentes em cidades como Embu das Artes poderiam estar relacionados à s "formigas vestidas" criadas por Jules Martin, curiosa manufatura paulistana do último quartel do século XIX.Present in Brazil since the beginning of Portuguese colonization, crèche nativity scenes were soon adapted to local reality, a propitious circumstance for the appearance of heterodox conceptions and the use of exotic elements of the fauna and flora peculiar to each region. As records about insects are very uncommon, it is noteworthy that females of leaf-cutting ants, Atta sp. (Hymenoptera, Formicidae), were used to compose crèche nativity scenes in São Paulo State. Having subsisted at least up to the decade of 1960, the "ant crèches" of cities such as Embu das Artes could be related to the then famous "dressed ants" created by Jules Martin, a curious manufacture of the city of São Paulo in the last quarter of the 19th century
‘Massive potential’ or ‘safety risk’? Health worker views on telehealth in the care of older people and implications for successful normalization
ADVANCE integrated group intervention to address both substance use and intimate partner abuse perpetration by men in substance use treatment: a feasibility randomised controlled trial
Background: Substance use is a risk factor for intimate partner abuse (IPA) perpetration. Delivering perpetrator
interventions concurrently with substance use treatment shows promise.
Methods: The feasibility of conducting an efficacy and cost-effectiveness trial of the ADVANCE 16-week
intervention to reduce IPA by men in substance use treatment was explored. A multicentre, parallel group
individually randomised controlled feasibility trial and formative evaluation was conducted. Over three temporal
cycles, 104 men who had perpetrated IPA towards a female (ex) partner in the past year were randomly allocated
to receive the ADVANCE intervention + substance use treatment as usual (TAU) (n = 54) or TAU only (n = 50) and
assessed 16-weeks post-randomisation. Participants’ (ex) partners were offered support and 27 provided outcome
data. Thirty-one staff and 12 men who attended the intervention participated in focus groups or interviews that
were analysed using the framework approach. Pre-specified criteria assessed the feasibility of progression to a
definitive trial: 1) ≥ 60% of eligible male participants recruited; 2) intervention acceptable to staff and male
participants; 3) ≥ 70% of participants followed-up and 4) levels of substance use and 5) IPA perpetrated by men in
the intervention arm did not increase from average baseline level at 16-weeks post-randomisation.
Results: 70.7% (104/147) of eligible men were recruited. The formative evaluation confirmed the intervention’s
acceptability. Therapeutic alliance and session satisfaction were rated highly. The overall median rate of intervention
session attendance (of 14 compulsory sessions) was 28.6% (range 14.3–64.3% by the third cycle). 49.0% (51/104) of
men and 63.0% (17/27) of their (ex) partners were followed-up 16-weeks post-randomisation. This increased to
100% of men and women by cycle three. At follow-up, neither substance use nor IPA perpetration had worsened
for men in the intervention arm.
Conclusions: It was feasible to deliver the ADVANCE intervention in substance use treatment services, although it
proved difficult to collect data from female (ex)partners. While some progression criteria were met, others were not,
although improvements were demonstrated by the third cycle. Lessons learned will be implemented into the study
design for a definitive trial of the ADVANCE intervention
Determination of unknown thermal coefficients in a Stefan problem for Storm’s type materials
Similarity solution for a two-phase one-dimensional Stefan problem with a convective boundary condition and a mushy zone model
Exact solution for a two-phase Stefan problem with variable latent heat and a convective boundary condition at the fixed face
Double Convergence of a Family of Discrete Distributed Mixed Elliptic Optimal Control Problems with a Parameter
Explicit solution for a two-phase fractional Stefan problem with a heat flux condition at the fixed face
Synthesis and Benzodiazepine Receptor Affinity of Derivatives of the New Tricyclic Heteroaromatic System Pyrido[3’,2’:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one
Derivatives 7-13 of a new tricyclic heteroaromatic system, pyrido[3′,2′:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one, were prepared as potential ligands at the benzodiazepine receptor, in view of their structural analogy with potent ligands such as the pyrazoloquinolines of the CGS series II, and especially with the benzothiopyrano[4,3-c]pyridazinones VI. They were obtained starting from the versatile ketones 2,3-dihydrothiopyrano[2,3-b] pyridin-4(4H)-one 1 and the corresponding 7-methyl derivative 2, via condensation with glyoxylic acid, and reaction of the intermediate acid mixtures with hydrazine or substituted phenylhydrazines. When evaluated for their binding affinity at the benzodiazepine receptor in bovine cortical membranes, the target compounds 8-13 displayed an affinity in the micromolar/submicromolar order. A hypothesis is presented to rationalize these results