Metallicity gradients in the Sagittarius dwarf spheroidal Galaxy

Metallicity gradients in the Sagittarius dwarf Galaxy (Sgr) are investigated by using infrared photometric data from the 2MASS survey. To search for metallicity effects, the giant branch in a field situated near the Center of the Sgr is compared to the giant branch in a field situated near its southern edge. The contamination of Sgr giant branch by foreground Galactic stars is canceled by statistical subtraction of diagrams symmetrical in Galactic latitude. After subtraction it is possible to reconstruct the Sgr giant branch with excellent accuracy. The giant branch in the two fields have similar slopes but are shifted in color. Even after correction for the differential reddening between the fields, the shift in color between the branch remains, and is very significant. This variation in the color of the giant branch corresponds to a metallicity variation of about -0.25 Dex. The existence of a metallicity gradient in Sgr may indicate that there are two different stellar population in Sgr. One has low metallicity, and another one of higher metallicity has a smaller spatial extension.Comment: 7 pages, 8 figures, A&A in pres

Stem cell therapy for reconstruction of alveolar cleft and trauma defects in adults: A randomized controlled, clinical trial

BackgroundStem cell therapy with bone marrow‐derived mesenchymal stem cells is a promising tissue engineering strategy to promote regeneration of craniofacial bone.PurposeTo determine whether cell therapy with ex vivo expanded stem cell populations would be safe and efficacious in the regeneration of large alveolar defects in patients with a history of cleft palate or craniofacial trauma.Materials and MethodsEighteen patients (10 patients with traumatic injury and 8 patients with cleft palate) presenting with missing teeth associated with horizontal alveolar bone deficiencies were included in this randomized controlled clinical trial. Patients were randomized to receive either conventional autogenous block grafts or stem cell therapy. After a healing period of 4 months the treated sites were re‐entered and the bone width re‐assessed prior to implant placement. Implant stability was evaluated through torque testing of the implant upon insertion and at 6 months postloading.ResultsThe mean gain in bone width was 1.5 ± 1.5 mm in the stem cell therapy group and 3.3 ± 1.4 mm in the control group. Overall, bone gain was higher in trauma patients as compared to patients with cleft palate, for both the control and the stem cell therapy groups. Most postoperative complications were wound dehiscences and incision line openings. Implants were placed successfully in 5 out of 10 patients in the stem cell therapy group and in all 8 patients in the control group. One implant from the control/cleft palate group failed before loading, while the rest of the implants were loaded successfully and remained stable at 6 months. The patients who did not receive implants were re‐treated with autogenous block bone graft.ConclusionThe ability of stem cells to treat large alveolar defects is safe, yet, their ability to completely reconstitute large alveolar defects is limited. This approach requires further optimization to meet the outcomes seen using current methods to treat large defects, particularly those resultant of cleft palate.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138871/1/cid12506.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138871/2/cid12506_am.pd

A review of implant provision for hypodontia patients within a Scottish referral centre

Background: Implant treatment to replace congenitally missing teeth often involves multidisciplinary input in a secondary care environment. High quality patient care requires an in-depth knowledge of treatment requirements. Aim: This service review aimed to determine treatment needs, efficiency of service and outcomes achieved in hypodontia patients. It also aimed to determine any specific difficulties encountered in service provision, and suggest methods to overcome these. Methods: Hypodontia patients in the Unit of Periodontics of the Scottish referral centre under consideration, who had implant placement and fixed restoration, or review completed over a 31 month period, were included. A standardised data collection form was developed and completed with reference to the patient's clinical record. Information was collected with regard to: the indication for implant treatment and its extent; the need for, complexity and duration of orthodontic treatment; the need for bone grafting and the techniques employed and indicators of implant success. Conclusion: Implant survival and success rates were high for those patients reviewed. Incidence of biological complications compared very favourably with the literature

A standard stellar library for evolutionary synthesis. III. Metallicity calibration

We extend the colour calibration of the widely used BaSeL standard stellar library (Lejeune, Cuisinier, & Buser 1997, 1998) to non-solar metallicities, down to [Fe/H] ~ -2.0 dex. Surprisingly, we find that at the present epoch it is virtually impossible to establish a unique calibration of UBVRIJHKL colours in terms of stellar metallicity [Fe/H] which is consistent simultaneously with both colour-temperature relations and colour-absolute magnitude diagrams (CMDs) based on observed globular cluster photometry data and on published, currently popular standard stellar evolutionary tracks and isochrones. The problem appears to be related to the long-standing incompleteness in our understanding of convection in late-type stellar evolution, but is also due to a serious lack of relevant observational calibration data that would help resolve, or at least further significant progress towards resolving this issue. In view of the most important applications of the BaSeL library, we here propose two different metallicity calibration versions: (1) the "WLBC 99" library, which consistently matches empirical colour-temperature relations and which, therefore, should make an ideal tool for the study of individual stars; and (2), the "PADOVA 2000" library, which provides isochrones from the Padova 2000 grid (Girardi et al., 2000) that successfully reproduce Galactic globular-cluster colour-absolute magnitude diagrams and which thus should prove particularly useful for studies of collective phenomena in stellar populations in clusters and galaxies.Comment: 15 pages, LaTeX, documentclass aa, accepted for A and

Counting and effective rigidity in algebra and geometry

The purpose of this article is to produce effective versions of some rigidity results in algebra and geometry. On the geometric side, we focus on the spectrum of primitive geodesic lengths (resp., complex lengths) for arithmetic hyperbolic 2-manifolds (resp., 3-manifolds). By work of Reid, this spectrum determines the commensurability class of the 2-manifold (resp., 3-manifold). We establish effective versions of these rigidity results by ensuring that, for two incommensurable arithmetic manifolds of bounded volume, the length sets (resp., the complex length sets) must disagree for a length that can be explicitly bounded as a function of volume. We also prove an effective version of a similar rigidity result established by the second author with Reid on a surface analog of the length spectrum for hyperbolic 3-manifolds. These effective results have corresponding algebraic analogs involving maximal subfields and quaternion subalgebras of quaternion algebras. To prove these effective rigidity results, we establish results on the asymptotic behavior of certain algebraic and geometric counting functions which are of independent interest.Comment: v.2, 39 pages. To appear in Invent. Mat

The Periotest Method: Implant-Supported Framework Precision of Fit Evaluation

: In this study, the Periotest instrument was used to measure the precision of fit between cast high noble-metal frameworks and the supporting implants in a patient-simulation model. Three framework conditions and three implant-location variables were used to evaluate the rigidity of the assembly as measured by the Periotest method. The framework variables were (1) one-piece castings (OPC); (2) sectioned-soldered inaccurate castings (SSIC); and (3) sectioned-soldered accurate castings (SSAC). The implant-location variables were right anterior (RA), center (C), and left anterior (LA). Materials and Methods : The patient simulation model used consisted of three self-tapping BrÅnemark implants in a reasonable arch curvature in bovine bone. Three working casts were fabricated from the patient-simulation model using polyvinyl siloxane and tapered impression copings. From the working casts, three sets of three frameworks were fabricated as OPCs, SSICs, and SSACs using type 3 high noble alloy. The SSICs were fabricated with a quantitative misfit of 101.6 Μm at the facial surface, between the abutment-to-gold cylinder interface at the C implant location. Periotest value (PTV) measurements were made at the midfacial surface of the frameworks directly above each abutment-to-gold cylinder interface. Three measurements were made for each test condition. The data were analyzed to compare framework condition(s) and implant location(s) using ANOVA and Fisher's Protected Least Significant Difference Comparison Test. Results : The ANOVA showed that significant differences exist between the mean PTV data for framework condition and for implant location (p < .01). Significant differences were shown between the mean PTV data for the SSAC assemblies and the OPC and SSIC assemblies. The SSICs displayed a more positive (+) mean PTV than the OPCs. The OPC assemblies had a more positive mean PTV than the SSAC assemblies. The mean PTV data for the SSAC assemblies had a significantly different PTV (p < .01) than the other two framework condition assemblies. The OPC and the SSIC assemblies had PTVs that were not significantly different. The C implant location was significantly different from the RA and the LA implant locations (p < .01). The RA and the LA implant locations were not significantly different from each other. The C implant location always demonstrated the most positive mean PTV regardless of the framework condition being tested. Conclusions : The Periotest instrument quantified differences in the precision of fit between three framework conditions. The SSAC assemblies were significantly more rigid than the OPC and SSIC assemblies. The OPC and SSIC assemblies' mean PTVs were not significantly different. The mean PTVs for the C implant location and the RA and LA implant locations were significantly different (p < .01). The mean PTVs of the RA and LA implant locations were not significantly different. The implant-location PTVs followed the same rank order for all three framework conditions. The procedures used to fabricate a more precise fit between the framework and the supporting implants is influenced by the skill of the clinician and technician.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75096/1/j.1532-849X.1996.tb00298.x.pd

The age of the Galactic thin disk from Th/Eu nucleocosmochronology I. Determination of [Th/Eu] abundance ratios

The purpose of this work is to resume investigation of Galactic thin disk dating using nucleocosmochronology with Th/Eu stellar abundance ratios, a theme absent from the literature since 1990. A stellar sample of 20 disk dwarfs/subgiants of F5 to G8 spectral types with -0.8 <= [Fe/H] <= +0.3 was selected. In stars with such spectral types and luminosity classes, spectral synthesis techniques must be employed if we wish to achieve acceptably accurate results. A homogeneous, self-consistent set of atmospheric parameters was determined. Effective temperatures were determined from photometric calibrations and H-alpha profile fitting; surface gravities were obtained from Teff, stellar masses and luminosities; microturbulence velocities and metallicities were obtained from detailed, differential spectroscopic analysis, relative to the Sun, using equivalent widths of Fe I and Fe II lines. Chemical abundances of the elements that contaminate the Th and Eu spectral regions (Ti, V, Cr, Mn, Co, Ni, Ce, Nd, and Sm) were determined through spectroscopic analysis. Abundance uncertainties were thoroughly scrutinised, their average value - (0.10 +/- 0.02) dex - being found to be satisfactorily low. Eu and Th abundances were determined by spectral synthesis of one Eu II line (4129.72 A) and one Th II line (4019.13 A), taking into account the detailed hyperfine structures of contaminating Co lines, as well as the hyperfine structure and isotope shift of the Eu line. Comparison of our abundances with literature data shows that our results exhibit a similar behaviour, but a considerably lower scatter (36% lower for Eu, and 61% lower for Th). The [Th/Eu] abundance ratios thus obtained were used, in the second paper of this series, to determine the age of the Galactic disk.Comment: 27 pages, 22 Postscript figures, accepted for publication in Astronomy & Astrophysics, final versio

ATP-Dependent Infra-Slow (<0.1 Hz) Oscillations in Thalamic Networks

An increasing number of EEG and resting state fMRI studies in both humans and animals indicate that spontaneous low frequency fluctuations in cerebral activity at <0.1 Hz (infra-slow oscillations, ISOs) represent a fundamental component of brain functioning, being known to correlate with faster neuronal ensemble oscillations, regulate behavioural performance and influence seizure susceptibility. Although these oscillations have been commonly indicated to involve the thalamus their basic cellular mechanisms remain poorly understood. Here we show that various nuclei in the dorsal thalamus in vitro can express a robust ISO at ∼0.005–0.1 Hz that is greatly facilitated by activating metabotropic glutamate receptors (mGluRs) and/or Ach receptors (AchRs). This ISO is a neuronal population phenomenon which modulates faster gap junction (GJ)-dependent network oscillations, and can underlie epileptic activity when AchRs or mGluRs are stimulated excessively. In individual thalamocortical neurons the ISO is primarily shaped by rhythmic, long-lasting hyperpolarizing potentials which reflect the activation of A1 receptors, by ATP-derived adenosine, and subsequent opening of Ba2+-sensitive K+ channels. We argue that this ISO has a likely non-neuronal origin and may contribute to shaping ISOs in the intact brain