The rich-club phenomenon across complex network hierarchies

The so-called rich-club phenomenon in a complex network is characterized when nodes of higher degree (hubs) are better connected among themselves than are nodes with smaller degree. The presence of the rich-club phenomenon may be an indicator of several interesting high-level network properties, such as tolerance to hub failures. Here we investigate the existence of the rich-club phenomenon across the hierarchical degrees of a number of real-world networks. Our simulations reveal that the phenomenon may appear in some hierarchies but not in others and, moreover, that it may appear and disappear as we move across hierarchies. This reveals the interesting possibility of non-monotonic behavior of the phenomenon; the possible implications of our findings are discussed.Comment: 4 page

Symbolic computations of non-linear observability

Date of Acceptance: 22/05/2015 ACKNOWLEDGEMENTS E.B.M. and M.S.B. acknowledge the Engineering and Physical Sciences Research Council (EPSRC), Grant No. EP/I032608/1. This work was done during a stay of E.B.M. at CORIA (Rouen) and a stay of C.L. at ICSMB (Aberdeen).Peer reviewedPublisher PD

Collective rearrangement at the onset of flow of a polycrystalline hexagonal columnar phase

Creep experiments on polycrystalline surfactant hexagonal columnar phases show a power law regime, followed by a drastic fluidization before reaching a final stationary flow. The scaling of the fluidization time with the shear modulus of the sample and stress applied suggests that the onset of flow involves a bulk reorganization of the material. This is confirmed by X-ray scattering under stress coupled to \textit{in situ} rheology experiments, which show a collective reorientation of all crystallites at the onset of flow. The analogy with the fracture of heterogeneous materials is discussed.Comment: to appear in Phys. Rev. Let

A symbolic network-based nonlinear theory for dynamical systems observability

EBM and MSB acknowledge the Engineering and Physical Sciences Research Council (EPSRC), grant Ref. EP/I032608/1. ISN acknowledges partial support from the Ministerio de Economía y Competitividad of Spain under project FIS2013-41057-P and from the Group of Research Excelence URJC-Banco de Santander.Peer reviewedPublisher PD

Sharp affine Sobolev type inequalities via the Lp Busemann–Petty centroid inequality

We show that the Lp Busemann-Petty centroid inequality provides an elementary and powerful tool to the study of some sharp affine functional inequalities with a geometric content, like log-Sobolev, Sobolev and Gagliardo-Nirenberg inequalities. Our approach allows also to characterize directly the corresponding equality cases.Coordenação de aperfeiçoamento de pessoal de nivel superiorInstituto Nacional de Matemática Pura e AplicadaConselho Nacional de Desenvolvimento Científico e TecnológicoFundação de Amparo a Pesquisa do Estado de Minas Gerai

Kairos: Efficient Temporal Graph Analytics on a Single Machine

Many important societal problems are naturally modeled as algorithms over temporal graphs. To date, however, most graph processing systems remain inefficient as they rely on distributed processing even for graphs that fit well within a commodity server's available storage. In this paper, we introduce Kairos, a temporal graph analytics system that provides application developers a framework for efficiently implementing and executing algorithms over temporal graphs on a single machine. Specifically, Kairos relies on fork-join parallelism and a highly optimized parallel data structure as core primitives to maximize performance of graph processing tasks needed for temporal graph analytics. Furthermore, we introduce the notion of selective indexing and show how it can be used with an efficient index to speedup temporal queries. Our experiments on a 24-core server show that our algorithms obtain good parallel speedups, and are significantly faster than equivalent algorithms in existing temporal graph processing systems: up to 60x against a shared-memory approach, and several orders of magnitude when compared with distributed processing of graphs that fit within a single server

Influence of Zinc Deficiency and Severe Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplatation

Hosp Israelita Albert Einstein, Oncol Hematol, Sao Paulo, BrazilHosp Israelita Albert Einstein, Dept Hematol & Oncol, Sao Paulo, BrazilHosp Israelita Albert Einstein, BMT, Sao Paulo, BrazilUniv Fed Sao Paulo, Endocrinol, Sao Paulo, BrazilUniv Fed Sao Paulo, Endocrinol, Sao Paulo, BrazilWeb of Scienc

Postnatal development of rats exposed to fluoxetine or venlafaxine during the third week of pregnancy

The aim of the present study was to compare the toxic effects of fluoxetine (F) (8 and 16 mg/kg) and venlafaxine (V) (40 and 80 mg/kg) administered during the third week of pregnancy on early development of rats. Both antidepressants were administered by gavage on pregnancy days 15 to 20 to groups of 10 to 12 animals each. Duration of gestation, food and water consumption, number of live pups and birth weight were recorded. Litters were culled to six pups at birth (day 1) and followed for growth until weaning (day 25). On day 60, a male and a female from each litter were injected with the 5-HT1 agonist, 5-methoxy-N,N-dimethyltryptamine (6 mg/kg, ip) and the serotonergic syndrome was graded. Fluoxetine but not venlafaxine reduced the duration of pregnancy when compared to the control (C) group (F = 21.1 days and C = 21.6 days, mean, P<0.02; maximum = 22 days and minimum = 21 days in both groups). The highest doses of both fluoxetine, 16 mg/kg (F16), and venlafaxine, 80 mg/kg (V80), reduced the food intake of pregnant rats, resulting in different rates of body weight gain during treatment (from pregnancy day 15 to day 20): F16 = 29.0 g, V80 = 28.7 g vs C = 39.5 g (median). Birth weight was influenced by treatment and sex (P<0.05; two-way ANOVA). Both doses of fluoxetine or venlafaxine reduced the body weight of litters; however, the body weight of litters from treated dams was equal to the weight of control litters by the time of weaning. At weaning there was no significant difference in weight between sexes. There was no difference among groups in number of live pups at birth, stillbirths, mortality during the lactation period or in the manifestation of serotonergic syndrome in adult rats. The occurrence of low birth weight among pups born to dams which did not show reduced food ingestion or reduction of body weight gain during treatment with lower doses of fluoxetine or venlafaxine suggests that these drugs may have a deleterious effect on prenatal development when administered during pregnancy. In addition, fluoxetine slightly but significantly affected the duration of pregnancy (about half a day), an effect not observed in the venlafaxine-treated groups.Universidade Federal FluminenseUniversidade Federal de São Paulo (UNIFESP)UNIFESPSciEL