76 research outputs found
Expansions for the Bollobas-Riordan polynomial of separable ribbon graphs
We define 2-decompositions of ribbon graphs, which generalise 2-sums and
tensor products of graphs. We give formulae for the Bollobas-Riordan polynomial
of such a 2-decomposition, and derive the classical Brylawski formula for the
Tutte polynomial of a tensor product as a (very) special case. This study was
initially motivated from knot theory, and we include an application of our
formulae to mutation in knot diagrams.Comment: Version 2 has minor changes. To appear in Annals of Combinatoric
Modeling electrolytically top gated graphene
We investigate doping of a single-layer graphene in the presence of
electrolytic top gating. The interfacial phenomena is modeled using a modified
Poisson-Boltzmann equation for an aqueous solution of simple salt. We
demonstrate both the sensitivity of graphene's doping levels to the salt
concentration and the importance of quantum capacitance that arises due to the
smallness of the Debye screening length in the electrolyte.Comment: 7 pages, including 4 figures, submitted to Nanoscale Research Letters
for a special issue related to the NGC 2009 conference
(http://asdn.net/ngc2009/index.shtml
Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant‐Associated Infection Surveillance Network ( TRANSNET )
Background Invasive fungal infections are a major cause of morbidity and mortality among solid organ transplant ( SOT ) and hematopoietic cell transplant ( HCT ) recipients, but few data have been reported on the epidemiology of endemic fungal infections in these populations. Methods Fifteen institutions belonging to the Transplant‐Associated Infection Surveillance Network prospectively enrolled SOT and HCT recipients with histoplasmosis, blastomycosis, or coccidioidomycosis occurring between March 2001 and March 2006. Results A total of 70 patients (64 SOT recipients and 6 HCT recipients) had infection with an endemic mycosis, including 52 with histoplasmosis, 9 with blastomycosis, and 9 with coccidioidomycosis. The 12‐month cumulative incidence rate among SOT recipients for histoplasmosis was 0.102%. Occurrence of infection was bimodal; 28 (40%) infections occurred in the first 6 months post transplantation, and 24 (34%) occurred between 2 and 11 years post transplantation. Three patients were documented to have acquired infection from the donor organ. Seven SOT recipients with histoplasmosis and 3 with coccidioidomycosis died (16%); no HCT recipient died. Conclusions This 5‐year multicenter prospective surveillance study found that endemic mycoses occur uncommonly in SOT and HCT recipients, and that the period at risk extends for years after transplantation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106980/1/tid12186.pd
Lessons learned and recommendations for data coordination in collaborative research: The CSER consortium experience
Integrating data across heterogeneous research environments is a key challenge in multi-site, collaborative research projects. While it is important to allow for natural variation in data collection protocols across research sites, it is also important to achieve interoperability between datasets in order to reap the full benefits of collaborative work. However, there are few standards to guide the data coordination process from project conception to completion. In this paper, we describe the experiences of the Clinical Sequence Evidence-Generating Research (CSER) consortium Data Coordinating Center (DCC), which coordinated harmonized survey and genomic sequencing data from seven clinical research sites from 2020 to 2022. Using input from multiple consortium working groups and from CSER leadership, we first identify 14 lessons learned from CSER in the categories of communication, harmonization, informatics, compliance, and analytics. We then distill these lessons learned into 11 recommendations for future research consortia in the areas of planning, communication, informatics, and analytics. We recommend that planning and budgeting for data coordination activities occur as early as possible during consortium conceptualization and development to minimize downstream complications. We also find that clear, reciprocal, and continuous communication between consortium stakeholders and the DCC is equally important to maintaining a secure and centralized informatics ecosystem for pooling data. Finally, we discuss the importance of actively interrogating current approaches to data governance, particularly for research studies that straddle the research-clinical divide
Tevatron Run-1 Z Boson Data and Collins-Soper-Sterman Resummation Formalism
We examine the effect of the Z-boson transverse momentum distribution
measured at the Run-1 of the Tevatron on the nonperturbative function of the
Collins-Soper-Sterman (CSS) formalism, which resums large logarithmic terms
from multiple soft gluon emission in hadron collisions. The inclusion of the
Tevatron Run-1 Z-boson data strongly favors a Gaussian form of the CSS
nonperturbative function, when combined with the other low energy Drell-Yan
data in a global fit.Comment: Published version; minor modifications, three references added; 19
pages, 7 figure
Learning difficulties : a portuguese perspective of a universal issue
In this article we present findings of a study that was conducted with the purpose of deepening the knowledge about the field of learning difficulties in Portugal. Therefore, within these findings we will discuss across several cultural boundaries, themes related with the existence of learning difficulties as a construct, the terminology, the political, social and scientific influences on the field, and the models of identification and of ongoing school support for students. While addressing the above-mentioned themes we will draw attention to the different, yet converging, international understandings of learning difficulties
25 Years of Self-organized Criticality: Concepts and Controversies
Introduced by the late Per Bak and his colleagues, self-organized criticality (SOC) has been one of the most stimulating concepts to come out of statistical mechanics and condensed matter theory in the last few decades, and has played a significant role in the development of complexity science. SOC, and more generally fractals and power laws, have attracted much comment, ranging from the very positive to the polemical. The other papers (Aschwanden et al. in Space Sci. Rev., 2014, this issue; McAteer et al. in Space Sci. Rev., 2015, this issue; Sharma et al. in Space Sci. Rev. 2015, in preparation) in this special issue showcase the considerable body of observations in solar, magnetospheric and fusion plasma inspired by the SOC idea, and expose the fertile role the new paradigm has played in approaches to modeling and understanding multiscale plasma instabilities. This very broad impact, and the necessary process of adapting a scientific hypothesis to the conditions of a given physical system, has meant that SOC as studied in these fields has sometimes differed significantly from the definition originally given by its creators. In Bak’s own field of theoretical physics there are significant observational and theoretical open questions, even 25 years on (Pruessner 2012). One aim of the present review is to address the dichotomy between the great reception SOC has received in some areas, and its shortcomings, as they became manifest in the controversies it triggered. Our article tries to clear up what we think are misunderstandings of SOC in fields more remote from its origins in statistical mechanics, condensed matter and dynamical systems by revisiting Bak, Tang and Wiesenfeld’s original papers
False‐positive Aspergillus galactomannan assay in solid organ transplant recipients with histoplasmosis
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91195/1/tid675.pd
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X-ray conversion physics
We have performed a series of experiments to study the physics of the conversion of 0.35-..mu..m laser light to soft x-rays in high-Z materials. The efficiency of soft x-ray and M-band radiation production as a function of laser intensity (5 /times/ 10/sup 13/ to 3 /times/ 10/sup 15/ W/cm/sup 2/) was measured. At fixed intensity 5 /times/ 10/sup 14/ W/cm/sup 2/, the time-resolved and time-integrated thermal x-ray (E < 1.5 keV) conversion efficiency increased with the laser pulse length for up to 4-ns-long pulses on gold targets. The effects of material opacity were examined by making targets of mixtures of gold and beryllium to vary the density of the strongly radiating gold in the target. These experiments demonstrate the effects of material opacity on both thermal and M-band x-ray production. These experiments were performed with large laser spots and greater than 1 kj of 0.35-..mu..m laser light using the Nova laser. These experiments have expanded our understanding of our ability to computer model the interaction of high intensity laser light with high-Z plasmas. 5 refs., 4 fig
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