Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise

Reasons for performing study: A change in management from pasture to stabling is a risk factor for equine colic. Objectives: To investigate the effect of a management change from pasture with no controlled exercise to stabling with light exercise on aspects of gastrointestinal function related to large colon impaction. The hypothesis was that drinking water intake, faecal output, faecal water content and large intestinal motility would be altered by a transition from a pastured to a stabled regime. Study design: Within-subject management intervention trial involving changes in feeding and exercise using noninvasive techniques. Methods: Seven normal horses were evaluated in a within-subjects study design. Horses were monitored while at pasture 24 h/day, and for 14 days following a transition to a stabling regime with light controlled exercise. Drinking water intake, faecal output and faecal dry matter were measured. Motility of the caecum, sternal flexure and left colon (contractions/min) were measured twice daily by transcutaneous ultrasound. Mean values were pooled for the pastured regime and used as a reference for comparison with stabled data (Days 1–14 post stabling) for multilevel statistical analysis. Results: Drinking water intake was significantly increased (mean ± s.d. pasture 2.4 ± 1.8 vs. stabled 6.4 ± 0.6 l/100 kg bwt/day), total faecal output was significantly decreased (pasture 4.62 ± 1.69 vs. stabled 1.81 ± 0.5 kg/100 kg bwt/day) and faecal dry matter content was significantly increased (pasture 18.7 ± 2.28 vs. stabled 27.2 ± 1.93% DM/day) on all days post stabling compared with measurements taken at pasture (P<0.05). Motility was significantly decreased in all regions of the large colon collectively on Day 2 post stabling (-0.76 contractions/min), and in the left colon only on Day 4 (-0.62 contractions/min; P<0.05). Conclusions: There were significant changes in large intestinal motility patterns and parameters relating to gastrointestinal water balance during a transition from pasture to stabled management, particularly during the first 5 days

Topology and chiral symmetry breaking in SU(N) gauge theories

We study the low-lying eigenmodes of the lattice overlap Dirac operator for SU(N) gauge theories with N=2,3,4 and 5 colours. We define a fermionic topological charge from the zero-modes of this operator and show that, as N grows, any disagreement with the topological charge obtained by cooling the fields, becomes rapidly less likely. By examining the fields where there is a disagreement, we are able to show that the Dirac operator does not resolve instantons below a critical size of about rho = 2.5 a, but resolves the larger, more physical instantons. We investigate the local chirality of the near-zero modes and how it changes as we go to larger N. We observe that the local chirality of these modes, which is prominent for SU(2) and SU(3), becomes rapidly weaker for larger N and is consistent with disappearing entirely in the limit of N -> infinity. We find that this is not due to the observed disappearance of small instantons at larger N.Comment: 41 pages, 12 figures, RevTe