Chagas disease knocks on our door : A cross-sectional study among Latin American immigrants in Milan, Italy

Objectives: We aimed to assess the prevalence and risk factors for Chagas disease (CD) in Latin American immigrants and to evaluate the accuracy of diagnostic tests. Moreover, we offered to all positive subjects a complete free-of-charge clinical/instrumental evaluation as well as benznidazole treatment in order to stage the disease and verify drug tolerability. Methods: A cross-sectional survey of CD among Latin Americans living in Milan and its metropolitan area was conducted between July 2013 and July 2014. Blood samples were tested for serologic evidence of CD together with a questionnaire covering demographic and clinical-epidemiological information. Results: Forty-eight (9.6%) of the 501 tested subjects were conclusively diagnosed as having CD. The highest prevalence of CD was among those from Bolivia (43/169, 25.4%) and El Salvador (4/68, 5.9%). Older age (adjusted odds ratio (aOR)] 1.05, p =0.004), a Bolivian origin (aOR 8.80; p =0.003), being born in the department of Santa Cruz (aOR 3.72, p =0.047), having lived in mud houses (aOR 2.68; p =0.019), and having an affected relative (aOR 12.77, p =0.001) were independently associated with CD. The ARCHITECT Chagas test showed the highest sensitivity (100%) and specificity (99.8%). Twenty-nine of the subjects with CD (60.4%) underwent disease staging, 10 of whom (35.7%) showed cardiac and/or digestive involvement. Benznidazole treatment was associated with high frequency of adverse reactions (19/27, 70.4%) and permanent discontinuation (8/27, 29.6%). Conclusions: CD is highly prevalent among Bolivians and Salvadorans living in Milan. Regions with a large Latin American immigrant population should implement programmes of active detection and treatment

Corrigendum to “‘Bacteroides mediterraneensis’ sp. nov., a new human-associated bacterium isolated from ileum specimen”

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‘Colidextribacter massiliensis’ gen. nov., sp. nov., isolated from human right colon

We report here the main characteristics of ‘Colidextribacter massiliensis’ strain Marseille-P3083T (CSURP3083), which was isolated from a human right colon lavage sample

‘Millionella massiliensis’ gen. nov., sp. nov., a new bacterial species isolated from human right colon

We report here the main characteristics of ‘Millionella massiliensis’ strain Marseille-P3215T (= CSUR P3215), which was isolated from a human right colon liquid sample

“Ihuprevotella massiliensis” gen. nov., sp. nov., isolated from human gut

We report here the main characteristics of “Ihuprevotella massiliensis” strain Marseille-P2826T (CSURP 2826) that was isolated from a human right colon lavage sample

FONTEÑA, PAQUITA [Material gráfico]

Copia digital. Madrid : Ministerio de Educación, Cultura y Deporte, 201

‘Mediterranea massiliensis’ gen. nov., sp. nov., a new human-associated bacterium isolated from the right and left colon lavage of a 58-year-old patient

We report here the main characteristics of ‘Mediterranea massiliensis’ strain Marseille-P2645T (CSURP2645) that was isolated from stored samples of gut

‘Pseudoflavonifractor phocaeensis’ gen. nov., sp. nov., isolated from human left colon

We describe here characteristics of ‘Pseudoflavonifractor phocaeensis’ strain Marseille-P3064T, which was isolated from a human left colon wash sample

‘Marseilla massiliensis’ gen. nov., sp. nov., isolated from human right colon

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