509 research outputs found
El uso de los dispositivos móviles en clase de Historia : experiencia de uso de Kahoot como herramienta evaluadora
A pesar de la digitalización de la sociedad, y de la masiva presencia de medios tecnológicos empleados por el alumnado y profesorado en su vida diaria, el empleo integrado de las TIC en el proceso de enseñanza-aprendizaje en las aulas no ha sido tan impactante. De hecho, a pesar de contar, en muchas ocasiones, con los elementos básicos para su integración en el proceso de enseñanza-aprendizaje, el profesorado no se ha decantado por ellas como herramienta didáctica. En este estudio se va a poner de manifiesto la experiencia desarrollada en el IES Domingo Valdivieso (Mazarrón, Murcia) durante el curso académico 2015-16, basada en el empleo de dispositivos móviles para la evaluación de varios estándares de aprendizaje que forman parte de la asignatura Historia del Mundo Contemporáneo, de 1.º de Bachillerato, a través de la herramienta web Kahoot.Despite the digitization of society and the massive presence of the Information and Communication Technology (ICT) means used by students and teachers in their lifes, their integration into the teaching-learning process in classrooms has not been so important. In fact, although there are basic elements for inclusion in this process, teachers have not opted for them as a teaching tool. In this context, this study will present the experience developed during the 2015-16 academic year with a group of1st of further education students in the subject Contemporary World History, in secondary school Domingo Valdivieso (Mazarrón, Murcia), in which mobiles will be used to evaluate some learning standards through the web tool Kahoot
The direct hydrothermal deposition of cobalt-doped MoS2 onto fluorine-doped SnO2 substrates for catalysis of the electrochemical hydrogen evolution reaction
Metal chalcogenides, and doped molybdenum sulfides in particular, have considerable potential as earth-abundant electrocatalysts for the hydrogen evolution reaction. This is especially true in the case of solar-to-hydrogen devices, where an ability to deposit these materials on transparent substrates is therefore desirable. Hydrothermal methods are perhaps the most common route by which metal chalcogenide materials suitable for the hydrogen evolution reaction are produced. Such methods are simple and scalable, but the direct hydrothermal deposition of metal chalcogenides on transparent oxide electrodes has hitherto never been reported. Such an advance would greatly facilitate the expansion of the field by removing the requirement for separate hydrothermal-synthesis and catalyst-deposition steps. In this paper, we show that the ternary chalcogenide Co2Mo9S26 can be synthesised on a fluorine-doped tin oxide substrate by hydrothermal methods directly from solutions of the simple metal salts. These films display good activity for the hydrogen evolution reaction from acid solution, achieving current densities of 10 mA cm−2 at 260 mV overpotential with a Tafel slope of 64 mV per decade. Moreover, the resulting films can be made to be translucent, a very useful property which would allow light to be transmitted through the catalyst to an underlying light-harvesting array in any solar-to-hydrogen device employing this material at the cathode
Etude des résultats d'exploitation d'unités de pêche artisanale en Martinique
L'étude des résultats d'exploitations de 55 unités de pêche, durant la période de Miquelon (de Décembre à Juin 1986) fait apparaître des résultats économiques certes variables mais, dans l'ensemble, médiocres : sur les 1397 sorties observées, près de la moitié aboutit à un niveau de recette nette de coûts variables négative et un peu plus du quart de ces sorties dégage une recette nette de C.V. compris entre 0 et 499 francs. Sur les 55 unités de pêche étudiées, plus du tiers des patrons de pêcheurs ont un résultat négatif et près de 50 % ont "une part patron" mensualisée inférieure au SMIC (Résumé d'auteur
What can functional brain imaging teach us about remission of type 2 diabetes?
Aims: With a paradigm shift in attitudes towards type 2 diabetes (T2D), ‘weight loss responsive’ diabetes is now thought of as a curable disease state. As a result, national programmes are being orchestrated to induce T2D remission soon after diagnosis with aggressive dietary interventions—such as very low‐calorie diets (VLCD). However, dietary interventions to achieve weight loss and diabetes remission lack the same long‐term sustainability and cardiovascular risk reduction evidence as bariatric surgery. This review aims to explore how brain imaging has contributed to our understanding of human eating behaviours and how neural correlates are affected by T2D. Methods: We summarise functional MRI (fMRI) studies looking at human eating behaviour and obesity. We explore how these neural correlates are affected by insulin resistance and T2D itself as well as its different treatment approaches. Finally, we comment on the need for more personalised approaches to maintaining metabolic health and how fMRI studies may inform this. Conclusion: fMRI studies have helped to fashion our understanding of the neurobiology of human appetite and obesity. Improving our understanding of the neural implications of T2D that promote disadvantageous eating behaviours will enable prevention of disease as well as mitigation against a vicious cycle of metabolic dysfunction and associated cognitive complications
Mechanisms of Action of Bariatric Surgery on Body Weight Regulation
Bariatric surgery is an effective treatment modality for obesity and obesity-associated complications. Weight loss after bariatric surgery was initially attributed to anatomic restriction or reduced energy absorption, but now it is understood that surgery treats obesity by influencing the subcortical areas of the brain to lower adipose tissue mass. There are three major phases of this process: initially the weight loss phase, followed by a phase where weight loss is maintained, and in a subset of patients a phase where weight is regained. These phases are characterized by altered appetitive behavior together with changes in energy expenditure. The mechanisms associated with the rearrangement of the gastrointestinal tract include central appetite control, release of gut peptides, change in microbiota and bile acids. However, the exact combination and timing of signals remain largely unknown. [Abstract copyright: Copyright © 2023 Elsevier Inc. All rights reserved.
Harnessing the Melanocortin System in the control of food intake and glucose homeostasis
The central and peripheral melanocortin system, comprising of five receptors and their endogenous ligands, is responsible for a wide array of physiological functions such as skin pigmentation, sexual function and development, and inflammation. A growing body of both clinical and pre-clinical research is demonstrating the relevance of this system in metabolic health. Disruption of hypothalamic melanocortin signalling is the most common cause of monogenic obesity in humans. Setmelanotide, an FDA-approved analogue of alpha-melanocyte stimulating hormone (α-MSH) that functions by restoring central melanocortin signalling, has proven to be a potent pharmacological tool in the treatment of syndromic obesity. As the first effective therapy targeting the melanocortin system to treat metabolic disorders, its approval has sparked research to further harness the links between these melanocortin receptors and metabolic processes. Here, we outline the structure of the central and peripheral melanocortin system, discuss its critical role in the regulation of food intake, and review promising targets that may hold potential to treat metabolic disorders in humans.</p
Mechanisms of weight loss after obesity surgery
Obesity surgery remains the most effective treatment for obesity and its complications. Weight loss was initially attributed to decreased energy absorption from the gut but have since been linked to reduced appetitive behaviour and potentially increased energy expenditure. Implicated mechanisms associating rearrangement of the gastrointestinal tract with these metabolic outcomes include central appetite control, release of gut peptides, change in microbiota and bile acids. However, the exact combination and timing of signals remain largely unknown. In this review, we survey recent research investigating these mechanisms, and seek to provide insights on unanswered questions over how weight loss is achieved following bariatric surgery which may eventually lead to safer, nonsurgical weight-loss interventions or combinations of medications with surger
- …