Is sea-basing a viable method of providing logistic support to the UK amphibious force?

Maritime power has traditionally been a central part of the UK’s defence planning and is well suited to supporting a wide range of military operations. The littoral area has always created problems for naval planners as most landings historically have had to endure a tactical separation of the naval and land components, and hence an artificial seam between the Navy and the Marines. With the end of the Cold War, amphibious operations are going to be more difficult to conduct than in the past, and amphibious forces are going to have to adopt manoeuvre warfare capabilities in order to successfully complete their missions. It is very likely that amphibious forces will have to conduct operations against a numerically superior enemy, who is on his own terrain, and be surrounded by a neutral, if not hostile populace. As such, the concept of Operational Manoeuvre From The Sea (OMFTS) whereby the sea is used as a manoeuvre space, and command and control is fast enough to cope with large amounts of information, but at the same time allow subordinates maximum flexibility to use their initiative, is increasingly attractive. It will be important not only for the combat elements to be able to use this new concept, but the Combat Service Support (CSS) elements as well

The poetry of Guy Butler

[From the introduction]: Guy Butler, born in Cradock on 21 January 1918, was a serious poet. Nearly a third of his poems are about death or loss, and many of the rest about parting failure, or difficult self-denial. His poetry is generally thoughtful and responsible to a deep religious vision. Of the ninety poems published between 1939 and 1979 the finest are those written between 1943 and 1963, from “Syrian Spring” to “Sweetwater.” The best poems cluster like moons round “On First Seeing Florence,” which is a major poem seldom given its rightful attention

Exploring the ‘middle ground’ between state and market: the example of China

Studies of housing systems lying in the ‘middle ground’ between state and market are subject to three important shortcomings. First, the widely used Esping-Andersen (EA) approach assesses only a subset of the key housing outcomes and may be less helpful for describing changes in housing policy regimes. Second, there is too much emphasis on tenure transitions, and an assumed close correspondence between tenure labels and effective system functioning may not be valid. Third, due attention has not been given to the spatial dimensions in which housing systems operate, in particular when housing policies have a significant devolved or localised emphasis. Updating EA’s framework, we suggest a preliminary list of housing system indicators in order to capture the nature of the housing systems being developed and devolved. We verified the applicability of this indicator system with the case of China. This illustrates clearly the need for a more nuanced and systematic basis for categorising differences and changes in welfare and housing policies

Mitoxantrone is superior to doxorubicin in a multiagent weekly regimen for patients older than 60 with high-grade lymphoma: results of a BNLI randomized trial of PAdriaCEBO versus PMitCEBO

A prospective, multicenter, randomized trial was undertaken to compare the efficacy and toxicity of adriamycin with mitoxantrone within a 6-drug combination chemotherapy regimen for elderly patients (older than 60 years) with high-grade non-Hodgkin lymphoma (HGL) given for a minimum of 8 weeks. A total of 516 previously untreated patients aged older than 60 years were randomized to receive 1 of 2 anthracycline-containing regimens: adriamycin, 35 mg/m2 intravenously (IV) on day 1 (n = 259), or mitoxantrone, 7 mg/m2 IV on day 1 (n = 257); with prednisolone, 50 mg orally on days 1 to 14; cyclophosphamide, 300 mg/m2 IV on day 1; etoposide, 150 mg/m2 IV on day 1; vincristine, 1.4 mg/m2 IV on day 8; and bleomycin, 10 mg/m2 IV on day 8. Each 2-week cycle was administered for a minimum of 8 weeks in the absence of progression. Forty-three patients were ineligible for analysis. The overall and complete remission rates were 78% and 60% for patients receiving PMitCEBO and 69% and 52% for patients receiving PAdriaCEBO (P = .05, P = .12, respectively). Overall survival was significantly better with PMitCEBO than PAdriaCEBO (P = .0067). However, relapse-free survival was not significantly different (P = .16). At 4 years, 28% of PAdriaCEBO patients and 50% of PMitCEBO patients were alive (P = .0001). Ann Arbor stage III/IV, World Health Organization performance status 2-4, and elevated lactate dehydrogenase negatively influenced overall survival from diagnosis. In conclusion, the PMitCEBO 8-week combination chemotherapy regimen offers high response rates, durable remissions, and acceptable toxicity in elderly patients with HGL

Calcium supplements and cancer risk : a meta-analysis of randomised controlled trials

Peer reviewedPublisher PD

Defining spatial housing submarkets: Exploring the case for expert delineated boundaries

Although there are numerous reasons for real estate analysts to construct spatial housing submarkets, there is little clarity about how this might best be done in practice. The existing literature offers a variety of techniques including those based on principal components analysis, cluster analysis and a range of other statistical procedures. This paper asks whether, given their market expertise and their role in disseminating information, shaping search patterns and informing bid formation, real estate agents might offer an effective but less data intensive method of submarket construction. The empirical research is based on an experiment that compares the predictive of different sets of submarket boundaries constructed by using either standard statistical methods or through consultation with real estate agents and other market analysts. The analysis draws on housing transactions data from Istanbul, Turkey. While the results do not demonstrate the outright superiority of any single method, they do suggest that expert-defined boundaries tend to perform at least as well as alternative construction techniques. Importantly, the results suggest that agent-based methods for delineating submarket boundaries might be used with a degree of confidence by real estate analysts and planners in market contexts where rich micro-datasets are not readily available. This has been one of the constraints internationally on wider adoption of submarket boundaries as an analytical tool

Effect of calcium supplements on risk of myocardial infarction and cardiovascular events : meta-analysis

Peer reviewedPublisher PD

Public acceptability of financial incentives for smoking cessation in pregnancy and breastfeeding

Objective To survey public attitudes about incentives for smoking cessation in pregnancy and for breast feeding to inform trial design. Design Cross-sectional survey. Setting and participants British general public. Methods Seven promising incentive strategies had been identified from evidence syntheses and qualitative interview data from service users and providers. These were shopping vouchers for: (1) validated smoking cessation in pregnancy and (2) after birth; (3) for a smoke-free home; (4) for proven breast feeding; (5) a free breast pump; (6) payments to health services for reaching smoking cessation in pregnancy targets and (7) breastfeeding targets. Ipsos MORI used area quota sampling and home-administered computer-assisted questionnaires, with randomised question order to assess agreement with different incentives (measured on a five-point scale). Demographic data and target behaviour experience were recorded. Analysis used multivariable ordered logit models. Results Agreement with incentives was mixed (ranging from 34% to 46%) among a representative sample of 1144 British adults. Mean agreement score was highest for a free breast pump, and lowest for incentives for smoking abstinence after birth. More women disagreed with shopping vouchers than men. Those with lower levels of education disagreed more with smoking cessation incentives and a breast pump. Those aged 44 or under agreed more with all incentive strategies compared with those aged 65 and over, particularly provider targets for smoking cessation. Non-white ethnic groups agreed particularly with breastfeeding incentives. Current smokers with previous stop attempts and respondents who had breast fed children agreed with providing vouchers for the respective behaviours. Up to £40/month vouchers for behaviour change were acceptable (>85%). Conclusions Women and the less educated were more likely to disagree, but men and women of childbearing age to agree, with incentives designed for their benefit. Trials evaluating reach, impact on health inequalities and ethnic groups are required prior to implementing incentive interventions

Joint inversion of seismic and gravity data for lunar composition and thermal state

We invert the Apollo lunar seismic data set, together with lunar mass and moment of inertia, directly for the chemical composition and thermal state of the Moon. The lunar mantle and crust are modelled in the chemical system CaO-FeO-MgO-Al2O3-SiO2. The stable minerals, their seismic properties, and the bulk density are computed by Gibbs free energy minimization. Voigt-Reuss-Hill averaging is then used to compute seismic-wave velocity profiles, from which traveltimes are estimated, while mass and moment of inertia are obtained by integration of the density profile. Given this scheme, the data are jointly inverted using a Markov chain Monte Carlo algorithm, from which a range of compositions and temperatures fitting data within uncertainties are obtained. The analysis constrains the range of compositions, thermal states, mineralogy and physical structure of the lunar interior that are consistent with data. Additionally, the analysis provides estimates for the size and density of the lunar core. The inferred lunar compositions have lower Mg#s (∼83) than the Earth's mantle (∼89), suggesting that the Moon was derived from material other than the Earth's mantle. This supports giant impact simulations of lunar origin that show that more than 80 per cent of the material making up the Moon is derived from the impacto

Indexing and retrieval of free-form surfaces using self-organizing maps

This thesis describes the use of Self-Organizing Maps in combination with unique curvature based feature combinations and various training data sets as a clustering function to describe free-form surfaces. Our descriptor was successfully used as the basis of techniques that segmented, indexed and retrieved free-form surfaces represented as triangulated meshes