Geophysical Imaging of Watershed Subsurface Patterns and Prediction of Soil Texture and Water Holding Capacity

The spatial distribution of subsurface soil textural properties across the landscape is an important control on the hydrological and ecological function of a watershed. Traditional methods of mapping soils involving subjective assignment of soil boundaries are inadequate for studies requiring a quantitative assessment of the landscape and its subsurface connectivity and storage capacity. Geophysical methods such as electromagnetic induction (EMI) provide the possibility of obtaining high-resolution images across a landscape to identify subtle changes in subsurface soil patterns. In this work we show how EMI can be used to image the subsurface of a ∼38 ha watershed. We present an imaging approach using kriging to interpolate and sequential Gaussian simulation to estimate the uncertainty in the maps. We also explore the idea of difference ECa mapping to try to exploit changes in soil moisture to identify more hydrologically active locations. In addition, we use a digital elevation model to identify flow paths and compare these with the ECa measurement as a function of distance. Finally, we perform a more traditional calibration of ECa with clay percentage across the watershed and determine soil water holding capacity (SWHC). The values of SWHC range from 0.07 to 0.22 m3 m−3 across the watershed, which contrast with the uniform value of 0.13 derived from the traditional soil survey maps. Additional work is needed to appropriately interpret and incorporate EMI data into hydrological studies; however, we argue that there is considerable merit in identifying subsurface soil patterns from these geophysical images

The Fundamental Diagram of Pedestrian Movement Revisited

The empirical relation between density and velocity of pedestrian movement is not completely analyzed, particularly with regard to the `microscopic' causes which determine the relation at medium and high densities. The simplest system for the investigation of this dependency is the normal movement of pedestrians along a line (single-file movement). This article presents experimental results for this system under laboratory conditions and discusses the following observations: The data show a linear relation between the velocity and the inverse of the density, which can be regarded as the required length of one pedestrian to move. Furthermore we compare the results for the single-file movement with literature data for the movement in a plane. This comparison shows an unexpected conformance between the fundamental diagrams, indicating that lateral interference has negligible influence on the velocity-density relation at the density domain $1 m^{-2}<\rho<5 m^{-2}$. In addition we test a procedure for automatic recording of pedestrian flow characteristics. We present preliminary results on measurement range and accuracy of this method.Comment: 13 pages, 9 figure

Genetic background influences the 5XFAD Alzheimer\u27s disease mouse model brain proteome.

There is an urgent need to improve the translational validity of Alzheimer’s disease (AD) mouse models. Introducing genetic background diversity in AD mouse models has been proposed as a way to increase validity and enable the discovery of previously uncharacterized genetic contributions to AD susceptibility or resilience. However, the extent to which genetic background influences the mouse brain proteome and its perturbation in AD mouse models is unknown. In this study, we crossed the 5XFAD AD mouse model on a C57BL/6J (B6) inbred background with the DBA/2J (D2) inbred background and analyzed the effects of genetic background variation on the brain proteome in F1 progeny. Both genetic background and 5XFAD transgene insertion strongly affected protein variance in the hippocampus and cortex (n = 3,368 proteins). Protein co-expression network analysis identified 16 modules of highly co-expressed proteins common across the hippocampus and cortex in 5XFAD and non- transgenic mice. Among the modules strongly influenced by genetic background were those related to small molecule metabolism and ion transport. Modules strongly influenced by the 5XFAD transgene were related to lysosome/stress responses and neuronal synapse/signaling. The modules with the strongest relationship to human disease—neuronal synapse/signaling and lysosome/stress response—were not significantly influenced by genetic background. However, other modules in 5XFAD that were related to human disease, such as GABA synaptic signaling and mitochondrial membrane modules, were influenced by genetic background. Most disease-related modules were more strongly correlated with AD genotype in the hippocampus compared with the cortex. Our findings suggest that the genetic diversity introduced by crossing B6 and D2 inbred backgrounds influences proteomic changes related to disease in the 5XFAD model, and that proteomic analysis of other genetic backgrounds in transgenic and knock-in AD mouse models is warranted to capture the full range of molecular heterogeneity in genetically diverse models of AD

Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity

Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many molecular factors regulating the process of cardiac chamber ballooning have been identified, the cellular mechanisms underlying the chamber formation remain unclear. Here, we demonstrate that cardiac chambers remodel by cell neighbour exchange of cardiomyocytes guided by the planar cell polarity (PCP) pathway triggered by two non-canonical Wnt ligands, Wnt5b and Wnt11. We find that PCP signalling coordinates the localisation of actomyosin activity, and thus the efficiency of cell neighbour exchange. On a tissue-scale, PCP signalling planar-polarises tissue tension by restricting the actomyosin contractility to the apical membranes of outflow tract cells. The tissue-scale polarisation of actomyosin contractility is required for cardiac looping that occurs concurrently with chamber ballooning. Taken together, our data reveal that instructive PCP signals couple cardiac chamber expansion with cardiac looping through the organ-scale polarisation of actomyosin-based tissue tension

Convergence of dynamic vegetation net productivity responses to precipitation variability from 10 years of MODIS EVI

According to Global Climate Models (GCMs) the occurrence of extreme events of precipitation will be more frequent in the future. Therefore, important challenges arise regarding climate variability, which are mainly related to the understanding of ecosystem responses to changes in precipitation patterns. Previous studies have found that Above-ground Net Primary Productivity (ANPP) was positively related to increases in annual precipitation and this relation may converge across biomes during dry years. One challenge in studying this ecosystem response at the continental scale is the lack of ANPP field measurements over extended areas. In this study, the MODIS EVI was utilized as a surrogate for ANPP and combined with precipitation datasets from twelve different experimental sites across the United States over a 10-year period. Results from this analysis confirmed that integrated-EVI for different biomes converged toward common precipitation use efficiency during water-limited periods and may be a viable surrogate for ANPP measurements for further ecological research

Pedestrian, Crowd, and Evacuation Dynamics

This contribution describes efforts to model the behavior of individual pedestrians and their interactions in crowds, which generate certain kinds of self-organized patterns of motion. Moreover, this article focusses on the dynamics of crowds in panic or evacuation situations, methods to optimize building designs for egress, and factors potentially causing the breakdown of orderly motion.Comment: This is a review paper. For related work see http://www.soms.ethz.c

High-statistics modeling of complex pedestrian avoidance scenarios

Quantitatively modeling the trajectories and behavior of pedestrians walking in crowds is an outstanding fundamental challenge deeply connected with the physics of flowing active matter, from a scientific point of view, and having societal applications entailing individual safety and comfort, from an application perspective. In this contribution, we review a pedestrian dynamics modeling approach, previously proposed by the authors, aimed at reproducing some of the statistical features of pedestrian motion. Comparing with high-statistics pedestrian dynamics measurements collected in real-life conditions (from hundreds of thousands to millions of trajectories), we modeled quantitatively the statistical features of the undisturbed motion (i.e. in absence of interactions with other pedestrians) as well as the avoidance dynamics triggered by a pedestrian incoming in the opposite direction. This was accomplished through (coupled) Langevin equations with potentials including multiple preferred velocity states and preferred paths. In this chapter we review this model, discussing some of its limitations, in view of its extension toward a more complex case: the avoidance dynamics of a single pedestrian walking through a crowd that is moving in the opposite direction. We analyze some of the challenges connected to this case and present extensions to the model capable of reproducing some features of the motion

Enhanced empirical data for the fundamental diagram and the flow through bottlenecks

In recent years, several approaches for modelling pedestrian dynamics have been proposed and applied e.g. for design of egress routes. However, so far not much attention has been paid to their 'quantitative' validation. This unsatisfactory situation belongs amongst others on the uncertain and contradictory experimental data base. The fundamental diagram, i.e. the density-dependence of the flow or velocity, is probably the most important relation as it connects the basic parameter to describe the dynamic of crowds. But specifications in different handbooks as well as experimental measurements differ considerably. The same is true for the bottleneck flow. After a comprehensive review of the experimental data base we give an survey of a research project, including experiments with up to 250 persons performed under well controlled laboratory conditions. The trajectories of each person are measured in high precision to analyze the fundamental diagram and the flow through bottlenecks. The trajectories allow to study how the way of measurement influences the resulting relations. Surprisingly we found large deviation amongst the methods. These may be responsible for the deviation in the literature mentioned above. The results are of particular importance for the comparison of experimental data gained in different contexts and for the validation of models.Comment: A contribution to: Pedestrian and Evacuation Dynamics 2008 (Springer) 12 pages, 7 figure