17 research outputs found

    Village Baseline Study: Site Analysis Report for Kollo – Fakara, Niger (NI0111)

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    The village baseline study of Tigo ZĂ©no village in the CCAFS benchmark site Fakara in Niger took place from 23 to 25 of June 2011. Focus group discussions were conducted separately for men and women. Tigo ZĂ©no’s natural resources are degraded, with sparse tree population. Water is scarce and temporary, the farmlands have eroded, and soil is infertile with low productivity. People are particularly concerned about the presence and expansion of gullies (“koris”) that have created uncultivable areas, major declines in soil fertility, destruction of crops during serious overflow of ponds and heavy rainfall, and significant reduction in the size of farmlands, especially those belonging to women, who have smaller farmlands than men

    Village Baseline Study: Site Analysis Report for Yatenga – Tougou, Burkina Faso

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    The village baseline study of Kononga village in the CCAFS site Yatenga-Tougou in Burkina Faso took place from 19th to 21st July 2011. Focus group discussions were conducted separately for men and women. Male and female participants believe that the natural resources in the village are deteriorating due to population increase and labour shortages related to the exodus of young people to gold mining sites. The village’s vision of the future includes more productive and fertile farmland, a denser forest, deeper and wider water reservoirs, and more boreholes. The men identified 21 organisations in the village, including 9 operating at the community level, while women identified 17 organisations, 10 of which operate at the community level. Men are considered the most important personal source of information in the village. The regional directorate for agriculture, hydrology and fishery resources (DRAHRA) is the single most relevant institutional source of climate and weather information for both male and female participants. Men and women gather information from outside the village via radio broadcasting and particularly Radio “Voix du paysan” (Voice of the Farmer). The market is the most important channel of information access for women. Women have a substantial role in agriculture and livestock production, as well as natural resource management but they have limited access to land or to improved technology or equipment, and few training opportunities

    Village Baseline Study: Site Analysis Report for Segou – Cinzana, Mali (MA0109)

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    The village baseline study of Tongo village in the CCAFS benchmark site of Cinzana, Mali took place from 12 to 14 July 2011. Focus group discussions were conducted separately for men and women. The village has an abundance of natural resources such as savannah, grassland, ponds, farmlands and several kinds of socio-economic infrastructure. Some of the natural resources, however, are in a state of progressive degradation due to increase in human population; indiscriminate felling of trees; clearing of forests and deforestation; lack of rainfall; drought; and animal pressure

    Village Baseline Study: Site Analysis Report for Kaffrine – Kaffrine, Senegal

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    The village baseline study of Toune MosquĂ©e village in the CCAFS benchmark site Kaffrine in Senegal took place from June 2 to 4, 2011. Natural resources in the village are in a progressive state of degradation. The ‘protected’ forest has almost disappeared, the soils have low fertility and are degraded, and crop production is not sufficient to meet the food needs of a family throughout the year. Families must buy food to fill the gap in production. For that they harvest and sell forest products, which creates a vicious cycle of resource degradation. The male and female groups identified 35 organisations operating in the village including informal groups, state services, associations, NGOs and Muslim brotherhoods. While 18 of those work on food security issues, only 4 are involved in the management and protection of natural resources. Very few agricultural extension and training opportunities target women despite the women’s significant role in agriculture and livestock production. Women obtain information on livestock feeding techniques from people and organisations such as the horticultural project, women’s associations, and water and forest services. Men get information on soil inputs and soil fertility management from other farmers, organisations, radio and television, and from community leaders, notably the office of the village chief and the mosque on Fridays. The radio is the form of media most commonly used by the women but few women own a radio

    New reagents for actinide-lanthanide group separations

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    SIGLEAvailable from CEN Saclay, Service de Documentation, 91191 Gif-sur-Yvette Cedex (France) / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

    The peripheral nerve and the neuromuscular junction are affected in the tenascin-C-deficient mouse.

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    International audienceA thorough examination of the structure and plasticity of the neuromuscular system was performed in tenascin-C mutant mice deficient in tenascin-C. The study of the peripheral nerve revealed a number of abnormal features. In the motor nerve, numerous unmyelinated and myelinated fibers with degraded myelin were present. Schwann cell processes often enclosed degenerative terminals. Transgene (beta-galactosidase) expression analyzed at the ultrastructural level was found to be unequally distributed in the mutant's neuromuscular tissues. At the NMJ, preterminal disorganization was prevalent. Some axon terminals exhibited abnormal overgrowth. A surprising lack of beta-galactosidase expression at some cellular sites known to possess tenascin-C in wild type mice correlated best with marked changes in the cytoarchitecture of the peripheral nerve and NMJ. In some other -but not all- cellular sites which normally express the molecule, immunofluorescence analysis suggested the presence of significant but low levels of tenascin-C-like immunoreactivity together with beta-galactosidase expression. Messenger RNA detection by RT-PCR confirmed the presence of low amounts of tenascin-C mRNA in skeletal muscle suggesting that the mice deficient in tenascin-C are not complete knock-outs of this gene, but low-expression mutants. Following in vivo injections of botulinum type-A toxin, we observed a greatly reduced sprouting response of the motor nerves in tenascin-C mutant mice. We also observed that N-CAM and beta-catenin were overexpressed in the mutant. Our results suggest that tenascin-C is involved both in stabilization and in plasticity of the NMJ
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