7,394 research outputs found
Rich Situated Attitudes
We outline a novel theory of natural language meaning, Rich
Situated Semantics [RSS], on which the content of sentential utterances
is semantically rich and informationally situated. In virtue of its situatedness,
an utteranceâs rich situated content varies with the informational
situation of the cognitive agent interpreting the utterance. In virtue of its
richness, this content contains information beyond the utteranceâs lexically
encoded information. The agent-dependence of rich situated content
solves a number of problems in semantics and the philosophy of language
(cf. [14, 20, 25]). In particular, since RSS varies the granularity of utterance
contents with the interpreting agentâs informational situation, it
solves the problem of finding suitably fine- or coarse-grained objects for
the content of propositional attitudes. In virtue of this variation, a layman
will reason with more propositions than an expert
The scale and persistence of soil moisture anomalies as simulated in a global model
Short term variability of climate is intimately connected with soil moisture variability. Soil moisture provides the storage and subsequent return to the atmosphere, through evaporation and transpiration, of precipitation anomalies over land. Global Circulation Model (GCM) simulations enable consistent identification of correlations and dynamical connections between the hydrologic variables, many of which are incompletely observed. One way to facilitate understanding with these increasingly intricate models is to perform sensitivity studies in which a boundary condition or process is prescribed. In this study we will report on a sensitivity study in which a GCM with a sophisticated land surface representation is used to investigate soil moisture variability in the model climate. The simulations to be used in this study were made at R15 resolution (approximately 4.5 deg latitude x 7.5 deg longitude) with prescribed sea surface temperatures (SST) in the GENESIS model (Thompson and Pollard, 1994), which is coupled to a Land Surface Transfer model (LSX) at 2 deg x 2 deg resolution (Pollard and Thompson, 1994). All the results represented here were taken from the monthly averages of the model results. The LSX model accounts for the physical effects of vegetation with two layers specified at each grid point. Vegetation attributes such as leaf area indices, fractional cover, leaf albedos, etc., were taken from the global dataset in Dorman and Sellers (1989). A six-layer soil model extends from the surface to 4.25 m depth. SST's were prescribed in two ten year experiments using monthly SST values with the daily value being interpolated from the nearest two months. In the first experiment monthly climatological values were used, and in the second, the Atmospheric Model Intercomparison Project (AMIP) observed SST's for the years 1979 through 1988 were used (Gates, 1992). Thus, the former experiment gives a measure of the intrinsic model variability, to be compared with that of the latter experiment, which includes month-to-month variability due to ocean forcing
Coupling biochemistry and mechanics in cell adhesion: a model for inhomogeneous stress fiber contraction
Biochemistry and mechanics are closely coupled in cell adhesion. At sites of
cell-matrix adhesion, mechanical force triggers signaling through the
Rho-pathway, which leads to structural reinforcement and increased
contractility in the actin cytoskeleton. The resulting force acts back to the
sites of adhesion, resulting in a positive feedback loop for mature adhesion.
Here we model this biochemical-mechanical feedback loop for the special case
when the actin cytoskeleton is organized in stress fibers, which are
contractile bundles of actin filaments. Activation of myosin II molecular
motors through the Rho-pathway is described by a system of reaction-diffusion
equations, which are coupled into a viscoelastic model for a contractile actin
bundle. We find strong spatial gradients in the activation of contractility and
in the corresponding deformation pattern of the stress fiber, in good agreement
with experimental findings.Comment: Revtex, 35 pages, 13 Postscript figures included, in press with New
Journal of Physics, Special Issue on The Physics of the Cytoskeleto
End states, ladder compounds, and domain wall fermions
A magnetic field applied to a cross linked ladder compound can generate
isolated electronic states bound to the ends of the chain. After exploring the
interference phenomena responsible, I discuss a connection to the domain wall
approach to chiral fermions in lattice gauge theory. The robust nature of the
states under small variations of the bond strengths is tied to chiral symmetry
and the multiplicative renormalization of fermion masses.Comment: 10 pages, 4 figures; final version for Phys. Rev. Let
Contraction of cross-linked actomyosin bundles
Cross-linked actomyosin bundles retract when severed in vivo by laser
ablation, or when isolated from the cell and micromanipulated in vitro in the
presence of ATP. We identify the time scale for contraction as a viscoelastic
time tau, where the viscosity is due to (internal) protein friction. We obtain
an estimate of the order of magnitude of the contraction time tau ~ 10-100 s,
consistent with available experimental data for circumferential microfilament
bundles and stress fibers. Our results are supported by an exactly solvable,
hydrodynamic model of a retracting bundle as a cylinder of isotropic, active
matter, from which the order of magnitude of the active stress is estimated.Comment: To be published in Physical Biolog
RISK MANAGEMENT FOR CHIROPRACTORS AND OSTEOPATHS: Neck Manipulation & Vertebrobasilar Stroke
Although rare, vertebrobasilar stroke is the best known of the possible side effects of cervical manipulation. Due to the serious sequelae that may result from cervical manipulation, chiropractors and osteopaths must take the appropriate steps to ensure the risk is minimised. This article outlines how the astute practitioner can minimise this risk. Practitioners must decide on the options for treatment of a patient with neck problems. Practitioners must also advise the patient of these options as part of an appropriate informed consent
From one cell to the whole froth: a dynamical map
We investigate two and three-dimensional shell-structured-inflatable froths,
which can be constructed by a recursion procedure adding successive layers of
cells around a germ cell. We prove that any froth can be reduced into a system
of concentric shells. There is only a restricted set of local configurations
for which the recursive inflation transformation is not applicable. These
configurations are inclusions between successive layers and can be treated as
vertices and edges decorations of a shell-structure-inflatable skeleton. The
recursion procedure is described by a logistic map, which provides a natural
classification into Euclidean, hyperbolic and elliptic froths. Froths tiling
manifolds with different curvature can be classified simply by distinguishing
between those with a bounded or unbounded number of elements per shell, without
any a-priori knowledge on their curvature. A new result, associated with
maximal orientational entropy, is obtained on topological properties of natural
cellular systems. The topological characteristics of all experimentally known
tetrahedrally close-packed structures are retrieved.Comment: 20 Pages Tex, 11 Postscript figures, 1 Postscript tabl
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