Performance Based Plastic Design of Concentrically Braced Frame attuned with Indian Standard code and its Seismic Performance Evaluation

In the Performance Based Plastic design method, the failure is predetermined; making it famous throughout the world. But due to lack of proper guidelines and simple stepwise methodology, it is not quite popular in India. In this paper, stepwise design procedure of Performance Based Plastic Design of Concentrically Braced frame attuned with the Indian Standard code has been presented. The comparative seismic performance evaluation of a six storey concentrically braced frame designed using the displacement based Performance Based Plastic Design (PBPD) method and currently used force based Limit State Design (LSD) method has also been carried out by nonlinear static pushover analysis and time history analysis under three different ground motions. Results show that Performance Based Plastic Design method is superior to the current design in terms of displacement and acceleration response. Also total collapse of the frame is prevented in the PBPD frame

Novel R2R Manufacturable Photonic-Enhanced Thin Film Solar Cells; January 28, 2010 -- January 31, 2011

Final subcontract report for PV Incubator project 'Novel R2R Manufacturable Photonic-Enhanced Thin Film Solar Cells.' The goal of this program was to produce tandem Si cells using photonic bandgap enhancement technology developed at ISU and Lightwave Power that would have an NREL-verified efficiency of 7.5% on 0.25 cm{sup 2} area tandem junction cell on plastic substrates. This goal was met and exceeded within the timeframe and budget of the program. On smaller area cells, the efficiency was even higher, {approx}9.5% (not verified by NREL). Appropriate polymers were developed to fabricate photonic and plasmonic devices on stainless steel, Kapton and PEN substrates. A novel photonic-plasmon structure was developed which shows a promise of improving light absorption in thin film cells, a better light absorption than by any other scheme

A model for reversible electroporation to deliver drugs into diseased tissues

Drug delivery through electroporation could be highly beneficial for the treatment of different types of diseased tissues within the human body. In this work, a mathematical model of reversible tissue electroporation is presented for injecting drug into the diseased cells. The model emphasizes the tissue boundary where the drug is injected as a point source. Drug loss from the tissue boundaries through extracellular space is studied. Multiple pulses are applied to deliver a sufficient amount of drug into the targeted cells. The set of differential equations that model the physical circumstances are solved numerically. This model obtains a mass transfer coefficient in terms of pore fraction coefficient and drug permeability. It controls the drug transport from extracellular to intracellular space. The drug penetration throughout the tissue is captured for the application of different pulses. The boundary effects on drug concentration are highlighted in this study. The advocated model is able to perform homogeneous drug transport into the cells so that the affected tissue is treated completely. This model can be applied to optimize clinical experiments by avoiding the lengthy and costly in vivo and in vitro experiments.Comment: 18 page

Magnification relations in gravitational lensing via multidimensional residue integrals

We investigate the so-called magnification relations of gravitational lensing models. We show that multidimensional residue integrals provide a simple explanation for the existence of these relations, and an effective method of computation. We illustrate the method with several examples, thereby deriving new magnification relations for galaxy lens models and microlensing (point mass lensing).Comment: 16 pages, uses revtex4, submitted to Journal of Mathematical Physic

Quantitative nucleotide level analysis of regulation of translation in response to depolarization of cultured neural cells

Studies on regulation of gene expression have contributed substantially to understanding mechanisms for the long-term activity-dependent alterations in neural connectivity that are thought to mediate learning and memory. Most of these studies, however, have focused on the regulation of mRNA transcription. Here, we utilized high-throughput sequencing coupled with ribosome footprinting to globally characterize the regulation of translation in primary mixed neuronal-glial cultures in response to sustained depolarization. We identified substantial and complex regulation of translation, with many transcripts demonstrating changes in ribosomal occupancy independent of transcriptional changes. We also examined sequence-based mechanisms that might regulate changes in translation in response to depolarization. We found that these are partially mediated by features in the mRNA sequence—notably upstream open reading frames and secondary structure in the 5′ untranslated region—both of which predict downregulation in response to depolarization. Translationally regulated transcripts are also more likely to be targets of FMRP and include genes implicated in autism in humans. Our findings support the idea that control of mRNA translation plays an important role in response to neural activity across the genome

A New Survey for Giant Arcs

We report on the first results of an imaging survey to detect strong gravitational lensing targeting the richest clusters selected from the photometric data of the Sloan Digital Sky Survey (SDSS) with follow-up deep imaging observations from the Wisconsin Indiana Yale NOAO (WIYN) 3.5m telescope and the University of Hawaii 88-inch telescope (UH88). The clusters are selected from an area of 8000 deg^2 using the Red Cluster Sequence technique and span the redshift range 0.1 < z < 0.6, corresponding to a comoving cosmological volume of ~ 2 Gpc^3. Our imaging survey thus targets a volume more than an order of magnitude larger than any previous search. A total of 240 clusters were imaged of which 141 had sub-arcsecond image quality. Our survey has uncovered16 new lensing clusters with definite giant arcs, an additional 12 systems for which the lensing interpretation is very likely, and 9 possible lenses which contain shorter arclets or candidate arcs which are less certain and will require further observations to confirm their lensing origin. The number of new cluster lenses detected in this survey is likely > 30. Among these new systems are several of the most dramatic examples of strong gravitational lensing ever discovered with multiple bright arcs at large angular separation. These will likely become 'poster-child' gravitational lenses similar to Abell 1689 and CL0024+1654. The new lenses discovered in this survey will enable future sysetmatic studies of the statistics of strong lensing and its implications for cosmology and our structure formation paradigm.Comment: 19 pages, 7 pages of Figures, submitted to AJ. Fixed Typo

Research on mechanisms of alloy strengthening. Part 1 - Strengthening through fine particle dispersion. Part 2 - Control of structure and properties by means of rapid quenching of liquid metals /splat cooling/ Semiannual report

Alloy strengthening mechanisms - strengthening by fine particle dispersion, and structure and properties control by rapid quenching or splat cooling of liquid metal