72 research outputs found
Superconductivity in a Molecular Metal Cluster Compound
Compelling evidence for band-type conductivity and even bulk
superconductivity below K has been found in
Ga-NMR experiments in crystalline ordered, giant Ga
cluster-compounds. This material appears to represent the first realization of
a theoretical model proposed by Friedel in 1992 for superconductivity in
ordered arrays of weakly coupled, identical metal nanoparticles.Comment: 5 pages, 4 figure
ΠΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎ-ΡΠ΅ΠΏΠ°ΡΠΈΡΡΡΡΠ΅Π΅ ΡΡΡΡΠΎΠΉΡΡΠ²ΠΎ Π΄Π»Ρ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠ³ΠΎ ΡΠ΅ΠΌΠ΅Π½ΠΎΠ²ΠΎΠ΄ΡΡΠ²Π° ΠΊΡΠΊΡΡΡΠ·Ρ
The development of domestic primary maize seed production requires the development of new threshing devices capable to minimize seed grains macro- and microdamage. (Research purpose) To justify the design and technological parameters of the axial-rotary threshing and separating device for varietal and hybrid maize with a device that ensures the cobs orientation in space before threshing and partial violation of their grain structure by friction during swirling by air flow. (Materials and methods) The authors used system analysis methods, ensuring the principle of flow in mechanized lines, building algorithms for the automated systems operation and designing agricultural machines. (Results and discussion) To minimize corn grain damage, the authors recommended the sequence of technological process operations of threshing with an axial-rotary threshing-separating device, into which the cobs were fed in a strictly oriented spatial position with a partially broken grain structure. They improved the orienting- dispensing loading device, presented in the form of a vortex orienting dispenser equipped with an automatic loading level control system. The authors established the design parameters of the vortex orienting batcher based on the experimental determination of the corn cobs mechanical and technological parameters. They proposed methods, equipment and devices for determining the angle of corn cobs repose. The authors calculated the dimensional parameters of the funnel window for the corn cob output and the metering vortex tube diameter. (Conclusions) The authors developed the design of a threshing-separating device with a device for orienting corn cobs in space before threshing and partial violation of their grain structure by friction during swirling by an air stream. They determined the funnel window optimal parameters at the bottom of the vortex orienting batcher: length β 0.378 meters, width β 0.122 meters, vortex tube diameter β at least 0.624 meters.Π Π°Π·Π²ΠΈΡΠΈΠ΅ ΠΎΡΠ΅ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠ³ΠΎ ΡΠ΅ΠΌΠ΅Π½ΠΎΠ²ΠΎΠ΄ΡΡΠ²Π° ΠΊΡΠΊΡΡΡΠ·Ρ ΡΡΠ΅Π±ΡΠ΅Ρ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ Π½ΠΎΠ²ΡΡ
ΠΎΠ±ΠΌΠΎΠ»Π°ΡΠΈΠ²Π°ΡΡΠΈΡ
ΡΡΡΡΠΎΠΉΡΡΠ², ΡΠΏΠΎΡΠΎΠ±Π½ΡΡ
ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ ΠΌΠ°ΠΊΡΠΎΠΈ ΠΌΠΈΠΊΡΠΎΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡ ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ Π·Π΅ΡΠ½Π°. (Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ) ΠΠ±ΠΎΡΠ½ΠΎΠ²Π°ΡΡ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠ²Π½ΠΎ-ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ Π°ΠΊΡΠΈΠ°Π»ΡΠ½ΠΎ-ΡΠΎΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎ-ΡΠ΅ΠΏΠ°ΡΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΡΡΡΠΎΠΉΡΡΠ²Π° Π΄Π»Ρ ΡΠΎΡΡΠΎΠ²ΠΎΠΉ ΠΈ Π³ΠΈΠ±ΡΠΈΠ΄Π½ΠΎΠΉ ΠΊΡΠΊΡΡΡΠ·Ρ Ρ ΠΏΡΠΈΡΠΏΠΎΡΠΎΠ±Π»Π΅Π½ΠΈΠ΅ΠΌ, ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°ΡΡΠΈΠΌ ΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΠΎΡΠ°ΡΠΊΠΎΠ² Π² ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅ ΠΏΠ΅ΡΠ΅Π΄ ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠΎΠΌ ΠΈ ΡΠ°ΡΡΠΈΡΠ½ΠΎΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ ΠΈΡ
Π·Π΅ΡΠ½ΠΎΠ²ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²ΠΎΠΌ ΡΡΠ΅Π½ΠΈΡ ΠΏΡΠΈ Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠΌ ΠΏΠ΅ΡΠ΅ΠΌΠ΅ΡΠ΅Π½ΠΈΠΈ Π²ΠΎΠ·Π΄ΡΡΠ½ΡΠΌ ΠΏΠΎΡΠΎΠΊΠΎΠΌ. (ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ) ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π°, ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΡΠΈΠ½ΡΠΈΠΏΠ° ΠΏΠΎΡΠΎΡΠ½ΠΎΡΡΠΈ Π² ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π»ΠΈΠ½ΠΈΡΡ
, ΠΏΠΎΡΡΡΠΎΠ΅Π½ΠΈΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΡΠ°Π±ΠΎΡΡ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΡΠΈΡΡΠ΅ΠΌ ΠΈ ΠΊΠΎΠ½ΡΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅Π»ΡΡΠΊΠΎΡ
ΠΎΠ·ΡΠΉΡΡΠ²Π΅Π½Π½ΡΡ
ΠΌΠ°ΡΠΈΠ½. (Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΡ) ΠΠ»Ρ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ Π·Π΅ΡΠ½Π° ΠΊΡΠΊΡΡΡΠ·Ρ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π»ΠΈ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΉ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠ° Π°ΠΊΡΠΈΠ°Π»ΡΠ½ΠΎ-ΡΠΎΡΠΎΡΠ½ΡΠΌ ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎ-ΡΠ΅ΠΏΠ°ΡΠΈΡΡΡΡΠΈΠΌ ΡΡΡΡΠΎΠΉΡΡΠ²ΠΎΠΌ, Π² ΠΊΠΎΡΠΎΡΠΎΠ΅ ΠΏΠΎΡΠ°ΡΠΊΠΈ ΠΏΠΎΠ΄Π°ΡΡΡΡ Π² ΡΡΡΠΎΠ³ΠΎ ΡΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅Π½Π½ΠΎΠΌ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠΈ Ρ ΡΠ°ΡΡΠΈΡΠ½ΠΎ Π½Π°ΡΡΡΠ΅Π½Π½ΠΎΠΉ Π·Π΅ΡΠ½ΠΎΠ²ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΠΎΠΉ. Π£ΡΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π»ΠΈ ΠΎΡΠΈΠ΅Π½ΡΠΈΡΡΡΡΠ΅-Π΄ΠΎΠ·ΠΈΡΡΡΡΠ΅Π΅ Π·Π°Π³ΡΡΠ·ΠΎΡΠ½ΠΎΠ΅ ΠΏΡΠΈΡΠΏΠΎΡΠΎΠ±Π»Π΅Π½ΠΈΠ΅, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΠΎΠ΅ Π² Π²ΠΈΠ΄Π΅ Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠ³ΠΎ ΠΎΡΠΈΠ΅Π½ΡΠΈΡΡΡΡΠ΅Π³ΠΎ Π΄ΠΎΠ·Π°ΡΠΎΡΠ°, ΠΎΡΠ½Π°ΡΠ΅Π½Π½ΠΎΠ³ΠΎ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠΎΠΉ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΡΡΠΎΠ²Π½Π΅ΠΌ Π·Π°Π³ΡΡΠ·ΠΊΠΈ. Π£ΡΡΠ°Π½ΠΎΠ²ΠΈΠ»ΠΈ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠ²Π½ΡΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠ³ΠΎ ΠΎΡΠΈΠ΅Π½ΡΠΈΡΡΡΡΠ΅Π³ΠΎ Π΄ΠΎΠ·Π°ΡΠΎΡΠ° Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΌΠ΅Ρ
Π°Π½ΠΈΠΊΠΎ-ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΎΠ² ΠΏΠΎΡΠ°ΡΠΊΠΎΠ² ΠΊΡΠΊΡΡΡΠ·Ρ. ΠΡΠ΅Π΄Π»ΠΎΠΆΠΈΠ»ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΡ, ΠΎΠ±ΠΎΡΡΠ΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΈ ΠΏΡΠΈΡΠΏΠΎΡΠΎΠ±Π»Π΅Π½ΠΈΡ Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΠ³Π»Π° Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΎΡΠΊΠΎΡΠ° ΠΏΠΎΡΠ°ΡΠΊΠΎΠ² ΠΊΡΠΊΡΡΡΠ·Ρ. Π Π°ΡΡΡΠΈΡΠ°Π»ΠΈ ΡΠ°Π·ΠΌΠ΅ΡΠ½ΡΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ ΠΎΠΊΠ½Π°-Π²ΠΎΡΠΎΠ½ΠΊΠΈ Π΄Π»Ρ Π²ΡΠ²ΠΎΠ΄Π° ΠΏΠΎΡΠ°ΡΠΊΠΎΠ² ΠΈ Π΄ΠΈΠ°ΠΌΠ΅ΡΡΠ° Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠΉ ΡΡΡΠ±Ρ Π΄ΠΎΠ·Π°ΡΠΎΡΠ°. (ΠΡΠ²ΠΎΠ΄Ρ) Π Π°Π·ΡΠ°Π±ΠΎΡΠ°Π»ΠΈ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΡ ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎΠ³ΠΎ-ΡΠ΅ΠΏΠ°ΡΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΡΡΡΠΎΠΉΡΡΠ²Π° Ρ ΠΏΡΠΈΡΠΏΠΎΡΠΎΠ±Π»Π΅Π½ΠΈΠ΅ΠΌ Π΄Π»Ρ ΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΡΠ°ΡΠΊΠΎΠ² Π² ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅ ΠΏΠ΅ΡΠ΅Π΄ ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠΎΠΌ ΠΈ ΡΠ°ΡΡΠΈΡΠ½ΡΠΌ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΈΡ
Π·Π΅ΡΠ½ΠΎΠ²ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²ΠΎΠΌ ΡΡΠ΅Π½ΠΈΡ ΠΏΡΠΈ Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠΌ ΠΏΠ΅ΡΠ΅ΠΌΠ΅ΡΠ΅Π½ΠΈΠΈ Π²ΠΎΠ·Π΄ΡΡΠ½ΡΠΌ ΠΏΠΎΡΠΎΠΊΠΎΠΌ. ΠΠΏΡΠ΅Π΄Π΅Π»ΠΈΠ»ΠΈ, ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ ΠΎΠΊΠ½Π°-Π²ΠΎΡΠΎΠ½ΠΊΠΈ Π² Π΄Π½Π΅ Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠ³ΠΎ ΠΎΡΠΈΠ΅Π½ΡΠΈΡΡΡΡΠ΅Π³ΠΎ Π΄ΠΎΠ·Π°ΡΠΎΡΠ°: Π΄Π»ΠΈΠ½Π° β 0,378 ΠΌΠ΅ΡΡΠ°, ΡΠΈΡΠΈΠ½Π° β 0,122 ΠΌΠ΅ΡΡΠ°, Π΄ΠΈΠ°ΠΌΠ΅ΡΡ Π²ΠΈΡ
ΡΠ΅Π²ΠΎΠΉ ΡΡΡΠ±Ρ β Π½Π΅ ΠΌΠ΅Π½Π΅Π΅ 0,624 ΠΌΠ΅ΡΡΠ°
Two novel mutations associated with ataxia-telangiectasia identified using an ion ampliSeq inherited disease panel
Β© 2017 Kuznetsova, Trofimov, Shubina, Kochetkova, Karetnikova, Barkov, Bakharev, Gusev and Sukhikh. Ataxia-telangiectasia (A-T), or Louis-Bar syndrome, is a rare neurodegenerative disorder associated with immunodeficiency. For families with at least one affected child, timely A-T genotyping during any subsequent pregnancy allows the parents to make an informed decision about whether to continue to term when the fetus is affected. Mutations in the ATM gene, which is 150 kb long, give rise to A-T; more than 600 pathogenic variants in ATM have been characterized since 1990 and new mutations continue to be discovered annually. Therefore, limiting genetic screening to previously known SNPs by PCR or hybridization with microarrays may not identify the specific pathog enic genotype in ATM for a given A-T family. However, recent developments in next-generation sequencing technology offer prompt high-throughput full-length sequencing of genomic fragments of interest. This allows the identification of the whole spectrum of mutations in a gene, including any novel ones. We report two A-T families with affected children and current pregnancies. Both families are consanguineous and originate from Caucasian regions of Russia and Azerbaijan. Before our study, no ATM mutations had been identified in the older children of these families. We used ion semiconductor sequencing and an Ion AmpliSeq β’ Inherited Disease Panel to perform complete ATM gene sequencing in a single member of each family. Then we compared the experimentally determined genotype with the affected/normal phenotype distribution in the whole family to provide unambiguous evidence of pathogenic mutations responsible for A-T. A single novel SNP was allocated to each family. In the first case, we found a mononucleotide deletion, and in the second, a mononucleotide insertion. Both mutations lead to truncation of the ATM protein product. Identification of the pathogenic mutation in each family was performed in a timely fashion, allowing the fetuses to be tested and diagnosed. The parents chose to continue with both pregnancies as both fetuses had a healthy genotype and thus were not at risk of A-T
Correlations Between Charge Ordering and Local Magnetic Fields in Overdoped YBaCuO
Zero-field muon spin relaxation (ZF-SR) measurements were undertaken on
under- and overdoped samples of superconducting YBaCuO to
determine the origin of the weak static magnetism recently reported in this
system. The temperature dependence of the muon spin relaxation rate in
overdoped crystals displays an unusual behavior in the superconducting state. A
comparison to the results of NQR and lattice structure experiments on highly
doped samples provides compelling evidence for strong coupling of charge, spin
and structural inhomogeneities.Comment: 4 pages, 4 figures, new data, new figures and modified tex
Spin dynamics and ordering of a cuprate stripe-antiferromagnet
In La1.48Nd0.4Sr0.12CuO4 the 139La and 63Cu NQR relaxation rates and signal
wipe-out upon lowering temperature are shown to be due to purely magnetic
fluctuations. They follow the same renormalized classical behavior as seen in
neutron data, when the electronic spins order in stripes, with a small spread
in spin stiffness (15% spread in activation energy). The La signal, which
reappears at low temperatures, is magnetically broadened and experiences
additional wipe-out due to slowing down of the Nd fluctuations.Comment: 4 pages including 3 figures - ref. 16 adde
First time determination of the microscopic structure of a stripe phase: Low temperature NMR in La2NiO4.17
The experimental observations of stripes in superconducting cuprates and
insulating nickelates clearly show the modulation in charge and spin density.
However, these have proven to be rather insensitive to the harmonic structure
and (site or bond) ordering. Using 139La NMR in La2NiO4.17, we show that in the
1/3 hole doped nickelate below the freezing temperature the stripes are
strongly solitonic and site ordered with Ni3+ ions carrying S=1/2 in the domain
walls and Ni2+ ions with S=1 in the domains.Comment: 4 pages including 4 figure
ΠΠ½Π΅Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠΈΡΡΠ΅ΠΌΠ° Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠ° ΠΊΡΠΊΡΡΡΠ·Ρ
Differentiation of the force applied to the cobs of seed corn in the process of threshing allows minimizing the amount of macro- and micro-damage to the grain, which maintains the potential yield level of this crop. (Research purpose) To develop an automatic control system for active pneumatic elements of the deck of the threshing-and-separating unit capable of varying the pressing force of the spikes applied to the cobs of seed corn in different parts of the threshing chamber to minimize the crop damage. (Materials and methods) The authors have used the methods of system analysis, designing the operating algorithms of automated mechanical systems, electronics and general electrical engineering. (Results and discussions) The authors offer an advanced design of the threshing-and-separating unit for seed corn. The design features an active pneumatic deck with an automatic control system varying the pressing force of separate deck spikes to the cob grain directly in the course of threshing. For air inflating and lowering, two valves are installed in each of the 16 airbags, 32 control relays being used. The operation process is automatized through the Atmega 2560 controller regulating the amount of pressure in the airbags forcing the spikes against the grain in the process of threshing. The authors propose a schematic diagram describing the operation algorithm of the controller with pressure control units in deck airbags. By programming the controller, an operator can change the amount of pressure in the airbags, thus adjusting the force of direct and precise pressing the deck spikes to the corn cobs, for any airbag and in any part of the deck. (Conclusions) It has been determined that the destructive pressing force of 55 Newtons can be achieved in certain combinations of the membrane thickness, the pressure in the airbags and the pressing depth of the spikes. The proposed design of the threshing device with a system of automated pressure control in the deck airbags allows varying the force of threshing, which minimizes the amount of macro- and micro-damage to the seed corn grain and thus maintains the potential yield level of this crop.ΠΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π²Π΅Π»ΠΈΡΠΈΠ½Ρ ΡΠΈΠ»ΠΎΠ²ΠΎΠ³ΠΎ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ Π½Π° ΠΏΠΎΡΠ°ΡΠΊΠΈ ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΊΡΠΊΡΡΡΠ·Ρ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠ° ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·ΠΈΡΡΠ΅Ρ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΌΠ°ΠΊΡΠΎ- ΠΈ ΠΌΠΈΠΊΡΠΎΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ Π·Π΅ΡΠ½Π°, ΡΡΠΎ ΡΠΎΡ
ΡΠ°Π½ΡΠ΅Ρ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π» ΡΡΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡΠΈ Π΄Π°Π½Π½ΠΎΠΉ ΠΊΡΠ»ΡΡΡΡΡ. (Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ) Π Π°Π·ΡΠ°Π±ΠΎΡΠ°ΡΡ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΡΡ ΡΠΈΡΡΠ΅ΠΌΡ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ Π°ΠΊΡΠΈΠ²Π½ΡΠΌΠΈ ΠΏΠ½Π΅Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΡΠ»Π΅ΠΌΠ΅Π½ΡΠ°ΠΌΠΈ Π΄Π΅ΠΊΠΈ ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎ-ΡΠ΅ΠΏΠ°ΡΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΡΡΡΠΎΠΉΡΡΠ²Π°, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΡΡ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°ΡΡ ΡΠΈΠ»Ρ ΠΏΡΠΈΠΆΠ°ΡΠΈΡ ΡΠΈΠΏΠΎΠ² ΠΊ ΠΏΠΎΡΠ°ΡΠΊΠ°ΠΌ ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΊΡΠΊΡΡΡΠ·Ρ Π² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
Π·ΠΎΠ½Π°Ρ
ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎΠΉ ΠΊΠ°ΠΌΠ΅ΡΡ, ΡΡΠΎΠ±Ρ ΡΠ½ΠΈΠ·ΠΈΡΡ ΡΡΠ°Π²ΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π·Π΅ΡΠ½Π°. (ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ) ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π°, ΠΏΡΠΎΠ΅ΠΊΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΡΠ°Π±ΠΎΡΡ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΌΠ΅Ρ
Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΈΡΡΠ΅ΠΌ, ΡΠ»Π΅ΠΊΡΡΠΎΠ½ΠΈΠΊΠΈ ΠΈ ΠΎΠ±ΡΠ΅ΠΉ ΡΠ»Π΅ΠΊΡΡΠΎΡΠ΅Ρ
Π½ΠΈΠΊΠΈ. (Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅) ΠΡΠ΅Π΄Π»ΠΎΠΆΠΈΠ»ΠΈ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΡ ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎ-ΡΠ΅ΠΏΠ°ΡΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΡΡΡΠΎΠΉΡΡΠ²Π° Π΄Π»Ρ ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΊΡΠΊΡΡΡΠ·Ρ. Π£ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠ²Π°Π»ΠΈ Π΅Π΅ Π°ΠΊΡΠΈΠ²Π½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π΄Π΅ΠΊΠΎΠΉ Ρ ΡΠΈΡΡΠ΅ΠΌΠΎΠΉ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠΈΠ»Ρ ΠΏΡΠΈΠΆΠ°ΡΠΈΡ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΡΡ
Π΄ΡΡΠ³ ΠΎΡ Π΄ΡΡΠ³Π° ΡΠΈΠΏΠΎΠ² Π΄Π΅ΠΊΠΈ ΠΊ Π·Π΅ΡΠ½Ρ, Π½Π°Ρ
ΠΎΠ΄ΡΡΠ΅ΠΌΡΡΡ Π² ΠΏΠΎΡΠ°ΡΠΊΠ΅, Π½Π΅ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²Π΅Π½Π½ΠΎ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠ°. ΠΠ»Ρ ΠΏΠΎΠ΄ΠΊΠ°ΡΠΊΠΈ ΠΈ ΡΠΏΡΡΠΊΠ° Π²ΠΎΠ·Π΄ΡΡ
Π° ΡΡΡΠ°Π½ΠΎΠ²ΠΈΠ»ΠΈ Π΄Π²Π° ΠΊΠ»Π°ΠΏΠ°Π½Π° Π² ΠΊΠ°ΠΆΠ΄ΠΎΠΉ ΠΈΠ· 16 ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠ΅ΠΊ, ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈ 32 ΡΠΏΡΠ°Π²Π»ΡΡΡΠΈΡ
ΡΠ΅Π»Π΅. ΠΠ»Ρ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠ° ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠ΅Π΄ΡΡΠΌΠΎΡΡΠ΅Π»ΠΈ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΠ΅ ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²ΠΎΠΌ ΠΊΠΎΠ½ΡΡΠΎΠ»Π»Π΅ΡΠ° Atmega 2560 Π΄Π°Π²Π»Π΅Π½ΠΈΡ Π² ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠΊΠ°Ρ
, ΠΏΡΠΈΠΆΠΈΠΌΠ°ΡΡΠΈΡ
ΡΠΈΠΏΡ ΠΊ Π·Π΅ΡΠ½Ρ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΎΠ±ΠΌΠΎΠ»ΠΎΡΠ°. ΠΠΏΡΠ΅Π΄Π΅Π»ΠΈΠ»ΠΈ ΠΏΡΠΈΠ½ΡΠΈΠΏΠΈΠ°Π»ΡΠ½ΡΡ ΡΡ
Π΅ΠΌΡ, ΠΎΠΏΠΈΡΡΠ²Π°ΡΡΡΡ Π°Π»Π³ΠΎΡΠΈΡΠΌ ΡΠ°Π±ΠΎΡΡ ΠΊΠΎΠ½ΡΡΠΎΠ»Π»Π΅ΡΠ° Ρ Π±Π»ΠΎΠΊΠ°ΠΌΠΈ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ Π΄Π°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ Π² ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠΊΠ°Ρ
Π΄Π΅ΠΊΠΈ. ΠΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΡΠΎ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΡ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΊΠΎΠ½ΡΡΠΎΠ»Π»Π΅ΡΠ° ΠΌΠΎΠΆΠ½ΠΎ ΠΈΠ·ΠΌΠ΅Π½ΡΡΡ Π΄Π°Π²Π»Π΅Π½ΠΈΠ΅ Π² ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠΊΠ°Ρ
ΠΈ ΡΠ΅ΠΌ ΡΠ°ΠΌΡΠΌ ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°ΡΡ ΡΠΈΠ»Ρ ΠΏΡΠΈΠΆΠ°ΡΠΈΡ ΡΠΈΠΏΠΎΠ² Π΄Π΅ΠΊΠΈ ΠΊ ΠΏΠΎΡΠ°ΡΠΊΠ°ΠΌ ΠΊΡΠΊΡΡΡΠ·Ρ Π°Π΄ΡΠ΅ΡΠ½ΠΎ, ΡΠΎ Π΅ΡΡΡ Π΄Π»Ρ Π»ΡΠ±ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠΊΠΈ Π² Π»ΡΠ±ΠΎΠΉ ΡΠ°ΡΡΠΈ Π΄Π΅ΠΊΠΈ. (ΠΡΠ²ΠΎΠ΄Ρ) ΠΠΏΡΠ΅Π΄Π΅Π»ΠΈΠ»ΠΈ, ΡΡΠΎ ΡΠ°Π·ΡΡΡΠ°ΡΡΠ΅Π΅ ΡΡΠΈΠ»ΠΈΠ΅ Π²Π΄Π°Π²Π»ΠΈΠ²Π°Π½ΠΈΡ 55 Π½ΡΡΡΠΎΠ½ΠΎΠ² Π΄ΠΎΡΡΠΈΠ³Π°Π΅ΡΡΡ Π² ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΡΡ
Π²Π°ΡΠΈΠ°Π½ΡΠ°Ρ
ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΡ ΡΠΎΠ»ΡΠΈΠ½Ρ ΠΌΠ΅ΠΌΠ±ΡΠ°Π½Ρ, Π΄Π°Π²Π»Π΅Π½ΠΈΡ Π² ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠΊΠ°Ρ
ΠΈ Π³Π»ΡΠ±ΠΈΠ½Ρ Π²Π΄Π°Π²Π»ΠΈΠ²Π°Π½ΠΈΡ ΡΠΈΠΏΠ°. Π Π°Π·ΡΠ°Π±ΠΎΡΠ°Π»ΠΈ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΡ ΠΌΠΎΠ»ΠΎΡΠΈΠ»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΎΠΉΡΡΠ²Π° Ρ ΡΠΈΡΡΠ΅ΠΌΠΎΠΉ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π΄Π°Π²Π»Π΅Π½ΠΈΡ Π² ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠΎΠ΄ΡΡΠΊΠ°Ρ
Π΄Π΅ΠΊΠΈ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΡΡ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°ΡΡ Π²Π΅Π»ΠΈΡΠΈΠ½Ρ ΠΎΠ±ΠΌΠΎΠ»Π°ΡΠΈΠ²Π°ΡΡΠΈΡ
ΡΠΈΠ», ΡΡΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·ΠΈΡΡΠ΅Ρ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΌΠ°ΠΊΡΠΎ- ΠΈ ΠΌΠΈΠΊΡΠΎΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ Π·Π΅ΡΠ½Π° ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΊΡΠΊΡΡΡΠ·Ρ
Impurity scattering effects on the low-temperature specific heat of d-wave superconductors
Very recently impurity scattering effects on quasiparticles in d-wave
superconductors have attracted much attention. Especially, the thermodynamic
properties in magnetic fields H are of interest. We have measured the
low-temperature specific heat C(T,H) of La_1.78Sr_0.22Cu_1-xNi_xO4. For the
first time, the impurity scattering effects on C(T,H) of cuprate
superconductors were clearly observed, and are compared with theory of d-wave
superconductivity. It is found that impurity scattering leads to
gamma(H)=gamma(0)(1+D((H/H_c2)(ln(H_c2/H)) in small magnetic fields. Most
amazingly, the scaling of C(T,H) breaks down due to impurity scattering.Comment: Physical review B, in pres
Maize Threshing and Separating Device for Primary Seed Production
The development of domestic primary maize seed production requires the development of new threshing devices capable to minimize seed grains macro- and microdamage. (Research purpose) To justify the design and technological parameters of the axial-rotary threshing and separating device for varietal and hybrid maize with a device that ensures the cobs orientation in space before threshing and partial violation of their grain structure by friction during swirling by air flow. (Materials and methods) The authors used system analysis methods, ensuring the principle of flow in mechanized lines, building algorithms for the automated systems operation and designing agricultural machines. (Results and discussion) To minimize corn grain damage, the authors recommended the sequence of technological process operations of threshing with an axial-rotary threshing-separating device, into which the cobs were fed in a strictly oriented spatial position with a partially broken grain structure. They improved the orienting- dispensing loading device, presented in the form of a vortex orienting dispenser equipped with an automatic loading level control system. The authors established the design parameters of the vortex orienting batcher based on the experimental determination of the corn cobs mechanical and technological parameters. They proposed methods, equipment and devices for determining the angle of corn cobs repose. The authors calculated the dimensional parameters of the funnel window for the corn cob output and the metering vortex tube diameter. (Conclusions) The authors developed the design of a threshing-separating device with a device for orienting corn cobs in space before threshing and partial violation of their grain structure by friction during swirling by an air stream. They determined the funnel window optimal parameters at the bottom of the vortex orienting batcher: length β 0.378 meters, width β 0.122 meters, vortex tube diameter β at least 0.624 meters
Two novel mutations associated with ataxia-telangiectasia identified using an ion ampliSeq inherited disease panel
Β© 2017 Kuznetsova, Trofimov, Shubina, Kochetkova, Karetnikova, Barkov, Bakharev, Gusev and Sukhikh. Ataxia-telangiectasia (A-T), or Louis-Bar syndrome, is a rare neurodegenerative disorder associated with immunodeficiency. For families with at least one affected child, timely A-T genotyping during any subsequent pregnancy allows the parents to make an informed decision about whether to continue to term when the fetus is affected. Mutations in the ATM gene, which is 150 kb long, give rise to A-T; more than 600 pathogenic variants in ATM have been characterized since 1990 and new mutations continue to be discovered annually. Therefore, limiting genetic screening to previously known SNPs by PCR or hybridization with microarrays may not identify the specific pathog enic genotype in ATM for a given A-T family. However, recent developments in next-generation sequencing technology offer prompt high-throughput full-length sequencing of genomic fragments of interest. This allows the identification of the whole spectrum of mutations in a gene, including any novel ones. We report two A-T families with affected children and current pregnancies. Both families are consanguineous and originate from Caucasian regions of Russia and Azerbaijan. Before our study, no ATM mutations had been identified in the older children of these families. We used ion semiconductor sequencing and an Ion AmpliSeq β’ Inherited Disease Panel to perform complete ATM gene sequencing in a single member of each family. Then we compared the experimentally determined genotype with the affected/normal phenotype distribution in the whole family to provide unambiguous evidence of pathogenic mutations responsible for A-T. A single novel SNP was allocated to each family. In the first case, we found a mononucleotide deletion, and in the second, a mononucleotide insertion. Both mutations lead to truncation of the ATM protein product. Identification of the pathogenic mutation in each family was performed in a timely fashion, allowing the fetuses to be tested and diagnosed. The parents chose to continue with both pregnancies as both fetuses had a healthy genotype and thus were not at risk of A-T
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