395 research outputs found
Modulation of the extraordinary optical transmission by surface acoustic waves
International audienceThe numerical study of periodically nanostructured metallic films exhibiting extraordinary optical transmission (EOT) deposited onto the top of a piezoelectric material is reported. Surface acoustic waves are generated in the piezoelectric substrate and their influence in the transmission spectrum of the EOT structure is studied. It is shown that low frequency acoustic waves can significantly tune the resonance frequency of the EOT structure
Technical and economic feasibility of the capture and geological storage of CO2 from a bio-fuel distillery: CPER Artenay project
AbstractThis paper first focuses on the environmental benefits of the CCS system applied to a bio-ethanol distillery before estimating its feasibility under geological and economic constraints.First, the calculation of CO2 balance in this application shows that the introduction of CO2 capture and sto rage in biomass energy systems (B-CCS) can si gnificantly increase the CO2 abat ement potential of the system and even leads to negative carbon emissions. Besides, a preliminary geological investigation reveals that the studied area has a good storage potential although the presence of major faults, while the low capture costs of CO2 from biomass fermentation emphasize the economic potential o f such a solution
Material anisotropy unveiled by random scattering of surface acoustic waves
We consider launching a monochromatic surface acoustic wave packet on a large set of random scatterers. The interference of the multiple scatteredwaves creates a random pattern of ripples on the crystal surface that is recorded by optical interferometry. The Fourier transform of the amplitude and phase data of the measured wave field unveils the complete slowness curve, i.e., the wave-vector as a function of the propagation angle. A simple acoustic speckle model is proposed to explain this observation.Peer reviewe
On a universal photonic tunnelling time
We consider photonic tunnelling through evanescent regions and obtain general
analytic expressions for the transit (phase) time (in the opaque barrier
limit) in order to study the recently proposed ``universality'' property
according to which is given by the reciprocal of the photon frequency.
We consider different physical phenomena (corresponding to performed
experiments) and show that such a property is only an approximation. In
particular we find that the ``correction'' factor is a constant term for total
internal reflection and quarter-wave photonic bandgap, while it is
frequency-dependent in the case of undersized waveguide and distributed Bragg
reflector. The comparison of our predictions with the experimental results
shows quite a good agreement with observations and reveals the range of
applicability of the approximated ``universality'' property.Comment: RevTeX, 8 pages, 4 figures, 1 table; subsection added with a new
experiment analyzed, some other minor change
Small Corrections to the Tunneling Phase Time Formulation
After reexamining the above barrier diffusion problem where we notice that
the wave packet collision implies the existence of {\em multiple} reflected and
transmitted wave packets, we analyze the way of obtaining phase times for
tunneling/reflecting particles in a particular colliding configuration where
the idea of multiple peak decomposition is recovered. To partially overcome the
analytical incongruities which frequently rise up when the stationary phase
method is adopted for computing the (tunneling) phase time expressions, we
present a theoretical exercise involving a symmetrical collision between two
identical wave packets and a unidimensional squared potential barrier where the
scattered wave packets can be recomposed by summing the amplitudes of
simultaneously reflected and transmitted wave components so that the conditions
for applying the stationary phase principle are totally recovered. Lessons
concerning the use of the stationary phase method are drawn.Comment: 14 pages, 3 figure
Respiratory modulation of oscillometric cuff pressure pulses and Korotkoff sounds during clinical blood pressure measurement in healthy adults
BACKGROUND:
Accurate blood pressure (BP) measurement depends on the reliability of oscillometric cuff pressure pulses (OscP) and Korotkoff sounds (KorS) for automated oscillometric and manual techniques. It has been widely accepted that respiration is one of the main factors affecting BP measurement. However, little is known about how respiration affects the signals from which BP measurement is obtained. The aim was to quantify the modulation effect of respiration on oscillometric pulses and KorS during clinical BP measurement.
METHODS:
Systolic and diastolic BPs were measured manually from 40 healthy subjects (from 23 to 65Â years old) under normal and regular deep breathing. The following signals were digitally recorded during linear cuff deflation: chest motion from a magnetometer to obtain reference respiration, cuff pressure from an electronic pressure sensor to derive OscP, and KorS from a digital stethoscope. The effects of respiration on both OscP and KorS were determined from changes in their amplitude associated with respiration between systole and diastole. These changes were normalized to the mean signal amplitude of OscP and KorS to derive the respiratory modulation depth. Reference respiration frequency, and the frequencies derived from the amplitude modulation of OscP and KorS were also calculated and compared.
RESULTS:
Respiratory modulation depth was 14 and 40 % for OscP and KorS respectively under normal breathing condition, with significant increases (both p  0.05) during deep breathing, and for the oscillometric signal during normal breathing (p > 0.05).
CONCLUSIONS:
Our study confirmed and quantified the respiratory modulation effect on the oscillometric pulses and KorS during clinical BP measurement, with increased modulation depth under regular deeper breathing
Efficiency of Collisionally-activated dissociation and 193-nm photodissociation of peptide ions in fourier transform mass spectrometry
AbstractFor tandem mass spectrometry, the Fourier transform instrument exhibits advantages for the use of collisionally-activated dissociation (CAD). The CAD energy deposited in larger ions can be greatly increased by extending the collision time to as much as 120 s, and the efficiency of trapping and measuring CAD product ions in many times greater than the found for triple-quadrupole or magnetic sector instruments, although the increased pressure from the collision gas is an offsetting disadvantage. A novel system that uses the same laser for photodesorption of ions and their subsequent photodissociation can produce complete dissociation of larger oligopeptide ions and unusually abundant fragment ions. In comparison to CAD, much more internal energy can be deposited in the primary ions using 193-nm photons, sufficient to dissociate peptide ions of m/z > 2000. Mass spectra closely resembling ion photodissociation spectra can also be obtained by neutral photodissociation (193-nm laser irradiation of the sample) followed by ion photodesorption
Role of plasma membrane lipid composition on cellular homeostasis: learning from cell line models expressing fatty acid desaturases
Experimental evidence has suggested that plasma membrane (PM)-associated signaling and hence cell metabolism and viability depend on lipid composition and organization. The aim of the present work is to develop a cell model to study the endogenous polyunsaturated fatty acids (PUFAs) effect on PM properties and analyze its influence on cholesterol (Chol) homeostasis. We have previously shown that by using a cell line over-expressing stearoyl-CoA-desaturase, membrane composition and organization coordinate cellular pathways involved in Chol efflux and cell viability by different mechanisms. Now, we expanded our studies to a cell model over-expressing both Δ5 and Δ6 desaturases, which resulted in a permanently higher PUFA content in PM. Furthermore, this cell line showed increased PM fluidity, Chol storage, and mitochondrial activity. In addition, human apolipoprotein A-I-mediated Chol removal was less efficient in these cells than in the corresponding control. Taken together, our results suggested that the cell functionality is preserved by regulating PM organization and Chol exportation and homeostasis.Fil: Jaureguiberry, MarĂa Soledad. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico la Plata. Instituto de Investigaciones BioquĂmicas de la Plata; Argentina. Universidad Nacional de La Plata; ArgentinaFil: Tricerri, Maria Alejandra. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico la Plata. Instituto de Investigaciones BioquĂmicas de la Plata; Argentina. Universidad Nacional de La Plata; ArgentinaFil: Sanchez, Susana A.. University Of California At Irvine. Laboratory of Fluorescence Dynamics; Estados UnidosFil: Finarelli, Gabriela Sandra. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico la Plata. Instituto de Investigaciones BioquĂmicas de la Plata; Argentina. Universidad Nacional de La Plata; ArgentinaFil: Montanaro, Mauro Aldo. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico la Plata. Instituto de Investigaciones BioquĂmicas de la Plata; Argentina. Universidad Nacional de La Plata; ArgentinaFil: Prieto, Eduardo Daniel. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico la Plata. Instituto de Investigaciones BioquĂmicas de la Plata; ArgentinaFil: Rimoldi, Omar Jorge. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico la Plata. Instituto de Investigaciones BioquĂmicas de la Plata; Argentina. Universidad Nacional de La Plata; Argentin
Fourier transform ion cyclotron resonance mass spectrometric detection of small Ca2+-induced conformational changes in the regulatory domain of human cardiac troponin C
AbstractTroponin C (TnC), a calcium-binding protein of the thin filament of muscle, plays a regulatory role in skeletal and cardiac muscle contraction. NMR reveals a small conformational change in the cardiac regulatory N-terminal domain of TnC (cNTnC) on binding of Ca2+ such that the total exposed hydrophobic surface area increases very slightly from 3090 ± 86 Å2 for apo-cNTnC to 3108 ± 71 Å2 for Ca2+-cNTnC. Here, we show that measurement of solvent accessibility for backbone amide protons by means of solution-phase hydrogen/deuterium (H/D) exchange followed by pepsin digestion, high-performance liquid chromatography, and electrospray ionization high-field (9.4 T) Fourier transform Ion cyclotron resonance mass spectrometry is sufficiently sensitive to detect such small ligand binding-induced conformational changes of that protein. The extent of deuterium incorporation increases significantly on binding of Ca2+ for each of four proteolytic segments derived from pepsin digestion of the apo- and Ca2+-saturated forms of cNTnC. The present results demonstrate that H/D exchange monitored by mass spectrometry can be sufficiently sensitive to detect and identify even very small conformational changes in proteins, and should therefore be especially informative for proteins too large (or too insoluble or otherwise intractable) for NMR analysis
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