A novel element upstream of the Vgamma2 gene in the murine T cell receptor gamma locus cooperates with the 3 enhancer to act as a locus control region.

Transgenic expression constructs were employed to identify a cis-acting transcription element in the T cell receptor (TCR)-gamma locus, called HsA, between the Vgamma5 and Vgamma2 genes. In constructs lacking the previously defined enhancer (3E(Cgamma1)), HsA supports transcription in mature but not immature T cells in a largely position-independent fashion. 3E(Cgamma1), without HsA, supports transcription in immature and mature T cells but is subject to severe position effects. Together, the two elements support expression in immature and mature T cells in a copy number-dependent, position-independent fashion. Furthermore, HsA was necessary for consistent rearrangement of transgenic recombination substrates. These data suggest that HsA provides chromatin-opening activity and, together with 3E(Cgamma1), constitutes a T cell-specific locus control region for the TCR-gamma locus

Detection and localization of continuous gravitational waves with pulsar timing arrays: the role of pulsar terms

A pulsar timing array is a Galactic-scale detector of nanohertz gravitational waves (GWs). Its target signals contain two components: the `Earth term' and the `pulsar term' corresponding to GWs incident on the Earth and pulsar respectively. In this work we present a Frequentist method for the detection and localization of continuous waves that takes into account the pulsar term and is significantly faster than existing methods. We investigate the role of pulsar terms by comparing a full-signal search with an Earth-term-only search for non-evolving black hole binaries. By applying the method to synthetic data sets, we find that (i) a full-signal search can slightly improve the detection probability (by about five percent); (ii) sky localization is biased if only Earth terms are searched for and the inclusion of pulsar terms is critical to remove such a bias; (iii) in the case of strong detections (with signal-to-noise ratio $\gtrsim$ 30), it may be possible to improve pulsar distance estimation through GW measurements.Comment: 12 pages, 9 figures, typos corrected. To match the published version. Code implementing this method is available at the PPTA Wiki pag

Anomalous particle-number fluctuations in a three-dimensional interacting Bose-Einstein condensate

The particle-number fluctuations originated from collective excitations are investigated for a three-dimensional, repulsively interacting Bose-Einstein condensate (BEC) confined in a harmonic trap. The contribution due to the quantum depletion of the condensate is calculated and the explicit expression of the coefficient in the formulas denoting the particle-number fluctuations is given. The results show that the particle-number fluctuations of the condensate follow the law $\sim N^{22/15}$ and the fluctuations vanish when temperature approaches to the BEC critical temperature.Comment: RevTex, 4 page

Thermoelectric Properties of Intermetallic Semiconducting RuIn3 and Metallic IrIn3

Low temperature (<400 K) thermoelectric properties of semiconducting RuIn3 and metallic IrIn3 are reported. RuIn3 is a narrow band gap semiconductor with a large n-type Seebeck coefficient at room temperature (S(290K)~400 {\mu}V/K), but the thermoelectric Figure of merit (ZT(290K) = 0.007) is small because of high electrical resistivity and thermal conductivity ({\kappa}(290 K) ~ 2.0 W/m K). IrIn3 is a metal with low thermopower at room temperature (S(290K)~20 {\mu}V/K) . Iridium substitution on the ruthenium site has a dramatic effect on transport properties, which leads to a large improvement in the power factor and corresponding Figure of merit (ZT(380 K) = 0.053), improving the efficiency of the material by an over of magnitude.Comment: Submitted to JA

Designing durable and flexible superhydrophobic coatings and its application in oil purification

Lotus-inspired superhydrophobic coatings are usually mechanically weak and lack durability, this hinders their practical applications. A suspension that can be treated on various materials in any size and shape to form a mechanically durable superhydrophobic coating is developed, which retains water repellent properties after multiple cycles of abrasion, blade scratching, tape-peeling, repeated deformation, a series of environmental tests and recycling. Based on its superhydrophobicity under oil, two highly efficient systems were developed for oil purification – stirring and inverted cone systems. Small water drops converge on the coated surface that was immersed in oil through velocity-controlled stirring, or designing an inverted cone superhydrophobic surface under oil to collect water drops spontaneously. This coating can be readily used for practical applications to make a durable superhydrophobic coating that functions either in air or oils

Influence of the Magnetic Coupling Process on the Advection Dominated Accretion Flows around Black Holes

A large-scale closed magnetic field can transfer angular momentum and energy between a black hole (BH) and its surrounding accretion flow. We investigate the effects of this magnetic coupling (MC) process on the dynamics of a hot accretion flow (e.g., an advection dominated accretion flow, hereafter ADAF). The energy and angular momentum fluxes transported by the magnetic field are derived by an equivalent circuit approach. For a rapidly rotating BH, it is found that the radial velocity and the electron temperature of the accretion flow decrease, whereas the ion temperature and the surface density increase. The significance of the MC effects depends on the value of the viscous parameter \alpha. The effects are obvious for \alpha=0.3 but nearly ignorable for \alpha=0.1. For a BH with specific angular momentum, a_*=0.9, and \alpha=0.3, we find that for reasonable parameters the radiative efficiency of a hot accretion flow can be increased by about 30%.Comment: 21 pages, 7 figures. Changed after the referee's suggestions. Accepted for publication in the Astrophysical Journa

Turbulent convection: comparing the moment equations to numerical simulations

The non-local hydrodynamic moment equations for compressible convection are compared to numerical simulations. Convective and radiative flux typically deviate less than 20% from the 3D simulations, while mean thermodynamic quantities are accurate to at least 2% for the cases we have investigated. The moment equations are solved in minutes rather than days on standard workstations. We conclude that this convection model has the potential to considerably improve the modelling of convection zones in stellar envelopes and cores, in particular of A and F stars.Comment: 10 pages (6 pages of text including figure captions + 4 figures), Latex 2e with AAS Latex 5.0 macros, accepted for publication in ApJ

Polarization and dispersion properties of elliptical hole golden spiral photonic crystal fiber

An elliptical air-hole golden spiral photonic crystal fiber (EGS-PCF) is analyzed with the full-vectorial finite element method. The air-holes in the EGS-PCF are arranged in a spiral pattern governed by the Golden Ratio, where the design has been inspired by the optimal arrangement of seeds found in nature. The EGS-PCF exhibits extremely high birefringence (∼0.022 at operating wavelength 1550 nm) which is particularly useful for generating a polarization stable supercontinuum (SC). The fiber can also be designed to have a Zero Dispersion Wavelength (ZDW) at a suitable wavelength for only one polarization and large negative dispersion for the other, leading to a single-polarization SC. In addition, the fiber dispersion can be designed to obtain ZDWs at 800 nm and 1064 nm simultaneously, which can facilitate broadband supercontinuum generation (SCG) through multi-wavelength pumping