598 research outputs found

    The Surface Chemical Properties of Novel High Surface Area Solids Synthesized from Coal Fly Ash

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    The zeolite, Na-P1, was synthesized from fly ash samples originating from coal-fired power stations in South Africa by hydrothermal treatment of the raw ash with concentrated aqueous NaOH solutions. The zeolite was then further modified by acid leaching at elevated temperatures. This resulted in the formation of a novel high surface-area solid. Spectroscopic and potentiometric investigations into the surface properties of both solids indicate that acid-base properties are most likely due to the presence of =AlOH- and =SiOH-type surface groups. Surface protonation constants for the various solids (unmodified ash, base-modified ash, acid-etched zeolitic product) are reported. Metal sorption studies were performed for cadmium and copper. It is suggested that the zeolitic product sorbs copper and cadmium by an ion exchange mechanism instead of a surface complexation mechanism, whereas the high surface-area solid, formed after acid etching, sorbs these metals via a surface complexation mechanism. Metal adsorption constants for the formation of =XOMOH species on the surface of the last mentioned solid for use in speciation models are reported. (South African Journal of Chemistry: 2003 56: 34-39

    Making it real: exploring the potential of Augmented Reality for teaching primary school science

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    The use of Augmented Reality (AR) in formal education could prove a key component in future learning environments that are richly populated with a blend of hardware and software applications. However, relatively little is known about the potential of this technology to support teaching and learning with groups of young children in the classroom. Analysis of teacher-child dialogue in a comparative study between use of an AR virtual mirror interface and more traditional science teaching methods for 10-year-old children, revealed that the children using AR were less engaged than those using traditional resources. We suggest four design requirements that need to be considered if AR is to be successfully adopted into classroom practice. These requirements are: flexible content that teachers can adapt to the needs of their children, guided exploration so learning opportunities can be maximised, in a limited time, and attention to the needs of institutional and curricular requirements

    Spatial characterization, resolution, and volumetric change of coastal dunes using airborne LIDAR: Cape Hatteras

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    ABSTRACT The technological advancement in topographic mapping known as airborne Light Detection and Ranging (LIDAR) allows researchers to gather highly accurate and densely sampled coastal elevation data at a rapid rate. The problem is to determine the optimal resolutions at which to represent coastal dunes for volumetric change analysis. This study uses digital elevation models (DEM) generated from LIDAR data and spatial statistics to better understand dune characterization at a series of spatial resolutions. The LIDAR data were collected jointly by the National Aeronautics and Space Administration (NASA), the National Oceanic and Atmospheric Administration (NOAA), and the U.S. Geological Survey (USGS). DEMs of two study sites (100×200 m) located in Cape Hatteras National Seashore, North Carolina were generated using a raster-based geographic information system (GIS). Changes in the dune volume were calculated for a 1-year period of time (Fall 1996(Fall -1997 at grid cell resolutions ranging from 1×1 to 20×20 m. Directional statistics algorithms were used to calculate local variance and characterize topographic complexity. Data processing was described in detail in order to provide an introduction to working with LIDAR data in a GIS. Results from these study sites indicated that a 1-2 m resolution provided the most reliable representation of coastal dunes on Cape Hatteras and most accurate volumetric change measurements. Results may vary at other sites and at different spatial extents, but the methods developed here can be applied to other locations to determine the optimum resolutions at which to represent and characterize topography using common GIS and database software

    Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses.

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    Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic, and transcriptional features of healing. Three full-thickness cutaneous wounds were created on each distal forelimb in six healthy horses, for a total of six wounds per horse. Umbilical cord-blood derived equine MSCs were applied to each wound 1 day after wound creation, in one of four forms: (a) normoxic- or (b) hypoxic-preconditioned cells injected into wound margins, or (c) normoxic- or (d) hypoxic-preconditioned cells embedded in an autologous fibrin gel and applied topically to the wound bed. Controls were one blank (saline) injected wound and one blank fibrin gel-treated wound per horse. Data were collected weekly for 6 weeks and included wound surface area, thermography, gene expression, and histologic scoring. Results indicated that MSC treatment by either delivery method was safe and improved histologic outcomes and wound area. Hypoxic-preconditioning did not offer an advantage. MSC treatment by injection resulted in statistically significant increases in transforming growth factor beta and cyclooxygenase-2 expression at week 1. Histologically, significantly more MSC-treated wounds were categorized as pro-healing than pro-inflammatory. Wound area was significantly affected by treatment: MSC-injected wounds were consistently smaller than gel-treated or control wounds. In conclusion, MSC therapy shows promise for distal extremity wounds in horses, particularly when applied by direct injection into the wound margin. Stem Cells Translational Medicine 2018;7:98-108

    Sub-wavelength terahertz beam profiling of a THz source via an all-optical knife-edge technique

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    Terahertz technologies recently emerged as outstanding candidates for a variety of applications in such sectors as security, biomedical, pharmaceutical, aero spatial, etc. Imaging the terahertz field, however, still remains a challenge, particularly when sub-wavelength resolutions are involved. Here we demonstrate an all-optical technique for the terahertz near-field imaging directly at the source plane. A thin layer (<100 nm-thickness) of photo carriers is induced on the surface of the terahertz generation crystal, which acts as an all-optical, virtual blade for terahertz near-field imaging via a knife-edge technique. Remarkably, and in spite of the fact that the proposed approach does not require any mechanical probe, such as tips or apertures, we are able to demonstrate the imaging of a terahertz source with deeply sub-wavelength features (<30 μm) directly in its emission plane

    Bringing school science to life: personalization, contextualization and reflection of self-collected data

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    Fast detector of the ellipticity of infrared and terahertz radiation based on HgTe quantum well structures

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    We report a fast, room temperature detection scheme for the polarization ellipticity of laser radiation, with a bandwidth that stretches from the infrared to the terahertz range. The device consists of two elements, one in front of the other, that detect the polarization ellipticity and the azimuthal angle of the ellipse. The elements respectively utilise the circular photogalvanic effect in a narrow gap semiconductor and the linear photogalvanic effect in a bulk piezoelectric semiconductor. For the former we characterized both a HgTe quantum well and bulk Te, and for the latter, bulk GaAs. In contrast with optical methods our device is an easy to handle all-electric approach, which we demonstrated by applying a large number of different lasers from low power, continuous wave systems to high power, pulsed sources.Comment: 7 pages, 5 figure

    Lipin-1 contributes to IL-4 mediated macrophage polarization

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    Macrophage responses contribute to a diverse array of pathologies ranging from infectious disease to sterile inflammation. Polarization of macrophages determines their cellular function within biological processes. Lipin-1 is a phosphatidic acid phosphatase in which its enzymatic activity contributes to macrophage pro-inflammatory responses. Lipin-1 also possesses transcriptional co-regulator activity and whether this activity is required for macrophage polarization is unknown. Using mice that lack only lipin-1 enzymatic activity or both enzymatic and transcriptional coregulator activities from myeloid cells, we investigated the contribution of lipin-1 transcriptional co-regulator function toward macrophage wound healing polarization. Macrophages lacking both lipin-1 activities did not elicit IL-4 mediated gene expression to levels seen in either wild-type or lipin-1 enzymatically deficient macrophages. Furthermore, mice lacking myeloid-associated lipin-1 have impaired full thickness excisional wound healing compared to wild-type mice or mice only lacking lipin-1 enzymatic activity from myeloid cell. Our study provides evidence that lipin-1 transcriptional co-regulatory activity contributes to macrophage polarization and influences wound healin
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