Northern-Most North American Flower Visitation Records of the Introduced Flower Fly, \u3ci\u3eSyritta Flaviventris\u3c/i\u3e (Diptera: Syrphidae) and Comparisons With Sympatric Species, \u3ci\u3eSyritta Pipiens\u3c/i\u3e

We report for the first time the syrphid fly, Syritta flaviventris (Macquart), collected in Lancaster County, Pennsylvania, as the northern-most record for this introduced Mediterranean species. In total, 3 male specimens and 1 female specimen were net collected on three flower species (Verbena hastata, Eryngium yuccifolium and Asclepias incarnata), at a single site of 11 monitored farm sites in southern Pennsylvania. Floral records for the similar introduced sibling species, Syritta pipiens (L.), are presented as well. Passive monitoring with colored pan traps used to monitor bee populations at these sites was not effective in collecting either species of Syritta. Our study suggests that increased active net sampling of Syritta species may provide more information about this genus\u27 distribution in the New World and support future research efforts examining Syritta biology and life history

Neurogenic Fever after Acute Traumatic Spinal Cord Injury: A Qualitative Systematic Review.

STUDY DESIGN: Systematic review. OBJECTIVE: To determine the incidence, pathogenesis, and clinical outcomes related to neurogenic fevers following traumatic spinal cord injury (SCI). METHODS: A systematic review of the literature was performed on thermodysregulation secondary to acute traumatic SCI in adult patients. A literature search was performed using PubMed (MEDLINE), Cochrane Central Register of Controlled Trials, and Scopus. Using strict inclusion and exclusion criteria, seven relevant articles were obtained. RESULTS: The incidence of fever of all origins (both known and unknown) after SCI ranged from 22.5 to 71.7% with a mean incidence of 50.6% and a median incidence of 50.0%. The incidence of fever of unknown origin (neurogenic fever) ranged from 2.6 to 27.8% with a mean incidence of 8.0% and a median incidence of 4.7%. Cervical and thoracic spinal injuries were more commonly associated with fever than lumbar injuries. In addition, complete injuries had a higher incidence of fever than incomplete injuries. The pathogenesis of neurogenic fever after acute SCI is not thoroughly understood. CONCLUSION: Neurogenic fevers are relatively common following an acute SCI; however, there is little in the scientific literature to help physicians prevent or treat this condition. The paucity of research underscored by this review demonstrates the need for further studies with larger sample sizes, focusing on incidence rate, clinical outcomes, and pathogenesis of neurogenic fever following acute traumatic SCI

Donor notification in reactive donors and their response to communication

Background: Blood transfusion is associated with the risk of transmitting transfusion transmissible infections (TTI) even after the thorough mandatory TTI screening of blood units. To prevent disease transmission, it is important to inform, notify and counsel the donors about their seroreactive status at the blood centre. The present study determines the response of various TTI reactive donors for post donation counselling after notification and their persistence in society as reactive donors.Methods: It was a retrospective study conducted at tertiary care center from 1May2015 to 30April2017. Re-active donors were called to the blood bank by telephonic call and letters. Reactive donors on complying at center were retested, counselled and referred to appropriate centre for further management.Results: There were 34,204 blood donations over period of two years, out of which 375[1.09%] were reactive donors. Of these HBV reactive comprises of 166/34204(0.48%), HCV were 40/34204(0.11%), HIV reactive donors comprises of 26/34204(0.07%), Syphilis 138/34204[0.40%] and there were five cases of co-infection, two for HIV+ HCV, two cases HIV+HBV and one case of co-infection with HBV+ Syphilis. A total of 375 TTI reactive donors were identified, out of which (227/375) 60.5% contacted by tele-phone calls and letters and remaining (148/375) 39.46% cannot be contacted. Out of 227 contacted donors only 117 donors reported for post donation counselling i.e. response rate of 51.54%.Conclusions: Donor notification is efficient method of curtailing TTI but undermined by communication failure with donors, resulting in persistent load of blood transmissible infectious risk

Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family.

BackgroundIt is now recognized that enzymatic or chemical side-reactions can convert normal metabolites to useless or toxic ones and that a suite of enzymes exists to mitigate such metabolite damage. Examples are the reactive imine/enamine intermediates produced by threonine dehydratase, which damage the pyridoxal 5'-phosphate cofactor of various enzymes causing inactivation. This damage is pre-empted by RidA proteins, which hydrolyze the imines before they do harm. RidA proteins belong to the YjgF/YER057c/UK114 family (here renamed the Rid family). Most other members of this diverse and ubiquitous family lack defined functions.ResultsPhylogenetic analysis divided the Rid family into a widely distributed, apparently archetypal RidA subfamily and seven other subfamilies (Rid1 to Rid7) that are largely confined to bacteria and often co-occur in the same organism with RidA and each other. The Rid1 to Rid3 subfamilies, but not the Rid4 to Rid7 subfamilies, have a conserved arginine residue that, in RidA proteins, is essential for imine-hydrolyzing activity. Analysis of the chromosomal context of bacterial RidA genes revealed clustering with genes for threonine dehydratase and other pyridoxal 5'-phosphate-dependent enzymes, which fits with the known RidA imine hydrolase activity. Clustering was also evident between Rid family genes and genes specifying FAD-dependent amine oxidases or enzymes of carbamoyl phosphate metabolism. Biochemical assays showed that Salmonella enterica RidA and Rid2, but not Rid7, can hydrolyze imines generated by amino acid oxidase. Genetic tests indicated that carbamoyl phosphate overproduction is toxic to S. enterica cells lacking RidA, and metabolomic profiling of Rid knockout strains showed ten-fold accumulation of the carbamoyl phosphate-related metabolite dihydroorotate.ConclusionsLike the archetypal RidA subfamily, the Rid2, and probably the Rid1 and Rid3 subfamilies, have imine-hydrolyzing activity and can pre-empt damage from imines formed by amine oxidases as well as by pyridoxal 5'-phosphate enzymes. The RidA subfamily has an additional damage pre-emption role in carbamoyl phosphate metabolism that has yet to be biochemically defined. Finally, the Rid4 to Rid7 subfamilies appear not to hydrolyze imines and thus remain mysterious

Iconicity emerges and is maintained in spoken language

Iconicity is the property whereby signs (vocal or manual) resemble their referents. Iconic signs are easy to relate to the world, facilitating learning and processing. In this study, we examined whether the benefits of iconicity would lead to its emergence and to maintenance in language. We focused on shape iconicity (the association between rounded objects and round-sounding words like “bouba” and between spiky objects and spiky-sounding words like “kiki”) and motion iconicity (the association between longer words and longer events). In Experiment 1, participants generated novel labels for round versus spiky shapes and long versus short movements (Experiment 1a: text, Experiment 1b: speech). Labels for each kind of stimulus differed in a way that was consistent with previous studies of iconicity. This suggests that iconicity emerges even on a completely unconstrainted task. In Experiment 2 (Experiment 2a: text, Experiment 2b: speech), we simulated language change in the laboratory (as iterated learning) and found that both forms of iconicity were introduced and maintained through generations of language users. Thus, we demonstrate the emergence of iconicity in spoken languages, and we argue that these results reflect a pressure for language systems to be referential, which favors iconic forms in the cultural evolution of language (at least up to a point where it is balanced by other pressures, e.g., discriminability). This can explain why we have iconicity across natural languages and may have implications for debates on language origins. (PsycInfo Database Record (c) 2021 APA, all rights reserved

Short run cost functions for Class II railroads / BEBR No.321

Includes bibliographical references