Magnetocaloric effect and critical behavior near the paramagnetic to ferrimagnetic phase transition temperature in TbCo2-xFex

Magnetocaloric effect (MCE) in TbCo2-xFex has been studied by dc magnetization measurements.On substituting Fe in TbCo2, not only the magnetic transition temperature is tuned to room temperature, but also the operating temperature range for MCE is increased from 50 K for TbCo2 to 95 K for TbCo1.9Fe0.1. The maximum magnetic entropy change (-{\Delta}SM) for TbCo1.9Fe0.1 is found to be 3.7 J kg-1 K-1 for a 5 T field change, making it a promising candidate for magnetic refrigeration near room temperature. The temperature dependent neutron diffraction study shows a structural phase transition (from cubic to rhombohedral phase with lowering of temperature) which is associated with the magnetic phase transition and these transitions broaden on Fe substitution. To investigate the nature of the paramagnetic to ferrimagnetic phase transition, we performed a critical exponent study. From the derived values of critical exponents, we conclude that TbCo2 belongs to the 3D Heisenberg class with short-range interaction, while on Fe substitution it tends towards mean-field with long-range interaction. The derived values of critical exponents represent the phenomenological universal curve for the field dependence of {\Delta}SM, indicating that TbCo2 and TbCo1.9Fe0.1 belong to two different universality classes.Comment: 12 figure

Magnetic properties of Hydrogenated Li and Co doped ZnO nanoparticles

The effect of hydrogenation on magnetic properties of Zn0.85Co0.05Li0.10O nanoparticles is presented. It was found that the sample hydrided at room temperature (RT) showed weak ferromagnetism (FM) while that hydrided at 400oC showed robust ferromagnetism at room temperature. In both cases reheating the sample at 400oC in air converts it back into paramagnetic state (P) completely. The characterization of samples by X-ray and electron diffraction (ED) showed that room temperature ferromagnetism observed in the samples hydrogenated at RT is intrinsic in nature whereas that observed in the samples hydrogenated at 400oC is partly due to the cobalt metal clusters.Comment: 10 pages, 3 figure

A comparative study of the antidepressant effect of ondansetron and granisetron on Albino mice

Background: Ondansetron and granisetron are selective 5-HT receptor antagonists used as antiemetics. The present study as aimed at comparing the antidepressant activity of ondansetron and granisetron in animal experimental models.Methods: The study was done after obtaining approval from the institutional animal ethical committee of JJM Medical college, Davangere and CPCSEA. A total of 24 mice of either sex and of weight between 20-40g were included in the study. The antidepressant activity of ondansetron and granisetron was evaluated in mice using forced swim test model (FST) and tail suspension test model (TST). In both the experimental models animals were divided into 4 groups and received the following drugs- Group 1 (control) - normal saline 10mg/kg i.p, Group 2 (standard)-fluoxetine 10mg/kg i.p, Group 3(test drug 1), ondansetron 2mg/kg i.p, Group 4 (test drug 2)- granisetron 0.5mg/kg i.p. The duration of immobility was noted and compared amongst the 4 groups in both the models 60 min after drug administration. The observations were analysed using ANOVA (one way) and post hoc Tukey’s test.Results: The test drugs showed significant reduction in duration of immobility in both the models. In FST and TST models, granisetron (0.5mg/kg i.p) showed a significant reduction in immobility period of 10.33 sec and 67 secs respectively when compared to ondansetron (2mg/kg i.p) and the standard drug fluoxetine (10mg/kg i.p).Conclusions: The results of study suggest that granisetron may be useful as a potential candidate for treatment of depression. Hence further animal studies with different model for depression and clinical studies should be conducted in order to choose the better drug for treatment PONV which is often associated with depression

Voice performance analysis using voice codec by packet fragmentation and contention free periods in wireless networks

The admission control is required to maintain the established route between the source and the destination in the wireless network. To maintain the stability of the route, the wireless channel parameters has to be adopted appropriately. Thus, this study analyzes the wireless access medium parameter through direct coordination (DCF) and point-to-point coordination method. The packets are fragmented in DCF and contention free period interval are adjusted to study the QoS parameters for various VOIP codec using OPNET simulation tool. The result shows that packet fragmentation to 256 bytes and contention free period for 20 ms improves QoS for G.729 for Voice traffic

Distraction Osteogenesis In The Management Of Temporomandibular Joint Ankylosis; Series of cases.

 Patients with temporomandibular joint ankylosis commonly present with mandibular hypoplasia as a result of trauma to the temporomandibular joint, middle ear infection or due to various syndromes. There is a wide acceptance of the conventional osteotomies for treating temporomandibular joint ankylosis, but there are certain limitations pertaining to them. In order to overcome these limitations several new approaches with modifications have been introduced. One among these is the method of gradual bone elongation known as distraction osteogenesis.  This process induces new bone formation along the vector of distraction force without requiring the use of a bone graft.   This study was conducted on four patients (2 females and 3 males within the age group of 16-30 years) in which 3 patients had bilateral temporomandibular joint ankylosis and one patient with unilateral temporomandibular joint ankylosis.. These patients underwent surgical correction of temporomandibular joint ankylosis and mandibular hypoplasia using distraction osteogenesis with extra-oral  distraction device under general anesthesia.In this study we have used extraoral device to achieve distraction more than 20 mm and to overcome the limitations of intra oral devices. This study concluded that distraction osteogenesis is the treatment of choice for the temporomandibular joint reconstruction and anterior linear advancement of the hypoplastic mandible in whom the mandibular advancement is highly difficult to be achieved by the conventional osteotomy procedures. The relapse rate over a period of 5 year is very minimal

Aeroelastic testing of LCA wing models - Model fabrication - Ground testing - Wind tunnel testing and Data analysis

Aeroelastic Testing Programme of Scaled Aeroelastic model of LCA half wing with rigid fuselage

Performance Analysis of the Gossip based Ad Hoc Routing using Received Signal Strength for AODV

In Mobile Ad hoc Networks (MANETs), congestion control is a critical issue in controlling the degradation of network performance. During the route discovery process, the MANET routing protocol floods control packets to discover routes which may cause congestion. Currently, routing protocols take the shortest path with the minimum number of hops to reach the destination without considering the effects of Received Signal Strength (RSS). During the route discovery process, each node of MANET should not blindly broadcast without considering RSS to avoid link breakage. This causes excess energy consumption in rediscovering new routes and a greater likelihood of network partition. This paper suggests a modification of the rebroadcasting procedure for Received Requests (RREQ) in AODV using RSS on Gossip algorithm (AODV-RG). The performance of the protocol is measured based on different scenarios through metrics such as packet delivery ratio, throughput and, end-to-end delay using Network Simulator (NS 3.24.1). Experimental results show that thee AODV-RG protocol outperforms that of AODV with gossip probability p=0.66 by minimizing RREQ rebroadcasting messages during route discovery process. The Ad hoc mobile networks are suffering from the scarce power in the nodes. To decrease the amount of power consumption the AODV has been developed by many researchers by introducing the GOSSIP probability to alter the flow of RREQ. The advantage of this scheme is to decrease the overheads and the busy time of the node by detecting the RSS of the receiving node. When RSS is more than the threshold, then the RREQ is forwarded. If RSS is less than the threshold value, then RREQ is ignored. We need to test if the GOSSIP use has affected positively the quality of performance parameters such as utilization, packet delay ratio and throughput of the RREQ rebroadcast and end-to-end delay

Sclerotium rolfsii Lectin Induces Stronger Inhibition of Proliferation in Human Breast Cancer Cells than Normal Human Mammary Epithelial Cells by Induction of Cell Apoptosis

Sclerotium rolfsii lectin (SRL) isolated from the phytopathogenic fungus Sclerotium rolfsii has exquisite binding specificity towards O-linked, Thomsen-Freidenreich (Galβ1-3GalNAcα1-Ser/Thr, TF) associated glycans. This study investigated the influence of SRL on proliferation of human breast cancer cells (MCF-7 and ZR-75), non-tumorigenic breast epithelial cells (MCF-10A) and normal mammary epithelial cells (HMECs). SRL caused marked, dose-dependent, inhibition of proliferation of MCF-7 and ZR-75 cells but only weak inhibition of proliferation of non-tumorigenic MCF-10A and HMEC cells. The inhibitory effect of SRL on cancer cell proliferation was shown to be a consequence of SRL cell surface binding and subsequent induction of cellular apoptosis, an effect that was largely prevented by the presence of inhibitors against caspases -3, -8, or -9. Lectin histochemistry using biotin-labelled SRL showed little binding of SRL to normal human breast tissue but intense binding to cancerous tissues. In conclusion, SRL inhibits the growth of human breast cancer cells via induction of cell apoptosis but has substantially less effect on normal epithelial cells. As a lectin that binds specifically to a cancer-associated glycan, has potential to be developed as an anti-cancer agent