True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant

True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant

Affirmed Crowd Sensor Selection based Cooperative Spectrum Sensing

The Cooperative Spectrum sensing model is gaining importance among the cognitive radio network sharing groups. While the crowd-sensing model (technically the cooperative spectrum sensing) model has positive developments, one of the critical challenges plaguing the model is the false or manipulated crowd sensor data, which results in implications for the secondary user’s network. Considering the efficacy of the spectrum sensing by crowd-sensing model, it is vital to address the issues of falsifications and manipulations, by focusing on the conditions of more accurate determination models. Concerning this, a method of avoiding falsified crowd sensors from the process of crowd sensors centric cooperative spectrum sensing has portrayed in this article. The proposal is a protocol that selects affirmed crowd sensor under diversified factors of the decision credibility about spectrum availability. An experimental study is a simulation approach that evincing the competency of the proposal compared to the other contemporary models available in recent literature

Assessment of an Integrated Nutrition Communication Approach to Educate the School Going Adolescent Girls Living In Urban Slums of Hyderabad, Telangana State, India

Purpose: Consumption of right diet during the adolescent phase is a critical issue among the adolescent population as their eating behavior is significantly influenced by the peers. Therefore, a study was carried out to educate the School going adolescent girls living in urban slums of Hyderabad, Telangana, India on right nutrition. Methods –The study was carried out in two randomly selected government schools after obtaining approval from the Scientific Advisory Committee (SAC). About 200 girls each from eighth and ninth standards were recruited as study subjects. The age of the participants ranged from 13-15 years. After obtaining baseline data, intervention was carried out on 8 focal themes related to nutrition, health and family life education, by using well designed educational material. Results: A significant increment in the knowledge levels on all the focal themes was observed among the adolescent girls in the experimental school. After completion of the study, considering the ethical issues, the control group was also given education on 8 focal themes. Conclusions and Implications: It was observed that an integrated approach in communication methods such as combining print media like charts, folders with electronic media, using CD alongside interpersonal communication significantly improved the knowledge levels of these girls on nutrition and family-life education

Invited commentary to the paper ‘Zinc status and its association with the health of adolescents: a review of studies in India’

We are pleased to view the article based on Dr. Rama Kawade's thesis illustrating the importance of micronutrient adequacy, especially zinc, and associated health implications in Indian adolescent girls. This brief commentary addresses three major aspects in which Kawade's work has made a significant contribution; nutrition and health issues of adolescents, rising importance of zinc in terms of deficiency problems being addressed, and development of dietary interventions to alleviate micronutrient deficiencies

Biochemical alterations of certain health parameters in cotton growing farmers exposed to organophosphorous and pyrethroid insecticides

A study was carried out on cotton growing farmers to assess the impact of organophosphorous pesticides on the biochemical parameters. Three hundred occupationally exposed farmers to pesticide application and equal number of unexposed subjects were selected from 24 randomly selected villages using stratified proportionate random sampling procedure. Multivariate logistic regression analysis was performed to assess the effect of pesticides on acetyl cholinesterase enzyme activity (AchE), in exposed and unexposed subjects. About 80% of exposed subjects used mixture of organophosphates and were exposed to pesticides for a period of 16.3 years at an average of 4 months / year. The severity of symptoms in the exposed subjects was higher in the second tertile (between 12 and 20 years) than in the third tertile (> 20 years). However, inhibition of AchE activity was significantly high (P < 0.05) in third tertile than the first (< 12 years) and second tertiles. Overall, there was a significant decrease in AchE activity and antioxidants with increased levels of lipid peroxidation (P < 0.01) in exposed subjects than unexposed subjects. The elevated levels of aspartate aminotransferase (AST) and creatinine in the exposed subjects were very marginal and just above the normal values.Key words: Chronic exposure, pesticides, AchE activity, lipid peroxidation

An External Beam Irradiation System for Trace Elemental Determination in Liquids

An external beam irradiation facility for direct trace elemental analysis of liquid samples has bean developed at the Variable Energy Cyclotron Centre, Calcutta. The system has been standardized primarily for transition metals, in liquid samples. The system has been found to behave lineraly over a wide range of concentrations. The minimum detection limits (MDL ) were found in the order of 15 -160 ppm in presence of interfering elements and 0.6 -10 ppm in the absence of interfering elements The results were validated by analysing NIST standards

Sulphited oils fatliquours from table

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