We don't know what you did last summer. On the importance of transparent reporting of reaction time data pre-processing

In behavioral, cognitive, and social sciences, reaction time measures are an important source of information. However, analyses on reaction time data are affected by researchers' analytical choices and the order in which these choices are applied. The results of a systematic literature review, presented in this paper, revealed that the justification for and order in which analytical choices are conducted are rarely reported, leading to difficulty in reproducing results and interpreting mixed findings. To address this methodological shortcoming, we created a checklist on reporting reaction time pre-processing to make these decisions more explicit, improve transparency, and thus, promote best practices within the field. The importance of the pre-processing checklist was additionally supported by an expert consensus survey and a multiverse analysis. Consequently, we appeal for maximal transparency on all methods applied and offer a checklist to improve replicability and reproducibility of studies that use reaction time measures

Replication and Fine Mapping for Association of the C2orf43, FOXP4, GPRC6A and RFX6 Genes with Prostate Cancer in the Chinese Population

Prostate cancer represents the leading cause of male death across the world. A recent genome-wide association study (GWAS) identified five novel susceptibility loci for prostate cancer in the Japanese population. This study is to replicate and fine map the potential association of these five loci with prostate cancer in the Chinese Han population.In Phase I of the study, we tested the five single nucleotide polymorphisms (SNPs) which showed the strongest association evidence in the original GWAS in Japanese. The study sample consists of 1,169 Chinese Hans, comprising 483 patients and 686 healthy controls. Then in phase II, flanking SNPs of the successfully replicated SNPs in Phase I were genotyped and tested for association with prostate cancer to fine map those significant association signals.We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer. The most significant odds ratio (OR) was recorded as 1.41 (95% confidence interval 1.18-1.68) for rs12653946. Rs9600079 did not show significant association (P = 8.07×10(-2)) with prostate cancer in this study. The Phase II study refined these association signals, and identified several SNPs showing more significant association with prostate cancer than the very SNPs tested in Phase I.Our results provide further support for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in Eastern Asian populations. This study also characterized the novel loci reported in the original GWAS with more details. Further work is still required to determine the functional variations and finally clarify the underlying biological mechanisms

We don't know what you did last summer. On the importance of transparent reporting of reaction time data pre-processing

In behavioral, cognitive, and social sciences, reaction time measures are an important source of information. However, analyses on reaction time data are affected by researchers' analytical choices and the order in which these choices are applied. The results of a systematic literature review, presented in this paper, revealed that the justification for and order in which analytical choices are conducted are rarely reported, leading to difficulty in reproducing results and interpreting mixed findings. To address this methodological shortcoming, we created a checklist on reporting reaction time pre-processing to make these decisions more explicit, improve transparency, and thus, promote best practices within the field. The importance of the pre-processing checklist was additionally supported by an expert consensus survey and a multiverse analysis. Consequently, we appeal for maximal transparency on all methods applied and offer a checklist to improve replicability and reproducibility of studies that use reaction time measures

Isolation of bacteria from soil surrounding of rafflesla Kerri Meijer in Lojing Highlands, Kelantan

Upstream Lojing Highland, Kelantan is chosen as the study area to isolate the bacteria from soil surrounding the Rafflesia kerri flower. Rqf/lesia kerri is attraction for tourist in the Lojing Highlands. The objectives of this study is to assess the distances association of soil bacteria from Rqfflesia kerri by identify the morphology characteristics of soil bacteria using Gram staining method. Soil samples were collected with different distances from the Rafflesia flower which are 20, 40 and 60 meters. A total number of 34 isolated bacteria were obtained growth on the Nutrient Agar plate. Gram staining method was used to determine Gram positive and negative bacteria by observed under light microscope. Morphology characteristics bacteria were characterized through form and Gram staining. The percentage form of bacteria obtained are as follows: irregular (38%), filamentous (29%), spindle and rhizoid both (12%) and circular (9%). Irregular form is the common shape for soil bacteria. Result from the Gram staining shows 65% of bacteria are from the Gram positive bacteria, meanwhile Gram negative are 35%. The results also identified that five species of bacteria inhabited on soil surrounding of Rqf/lesia kerri flower as follows: Corynebaclerium diphrheriae. Bacillus sublilis. Staphylococcus aureus, Escherichia coli and Spirilium volurans. As conclusion, number of colonies of soil sample collected from distances near to Rafllesia kerri ‘flower higher than distances far to flower and mostly the soil bacteria collected is irregular form and positive Gram bacteria

Şantierul arheologic Suceava (r. şi reg. Suceava)

Nestor Ion, Martinovici Trifu, Matei Mircea D., Diaconu Gheorghe, Olteanu Ştefan, Constantinescu Nicolae. Şantierul arheologic Suceava (r. şi reg. Suceava). In: Materiale şi cercetări arheologice, N°5 1959. pp. 593-618

Şantierul arheologic Suceava. Raport preliminar asupra săpăturilor din campania anului 1955 / Le chantier archéologique de Suceava

Nestor Ion, Diaconu Gheorghe, Matei Mircea D., Martinovici Trifu, Constantinescu Nicolae, Olteanu Ştefan. Şantierul arheologic Suceava. Raport preliminar asupra săpăturilor din campania anului 1955 / Le chantier archéologique de Suceava. In: Materiale şi cercetări arheologice, N°4 1957. pp. 239-278