483 research outputs found

    Search for the disappearance of muon antineutrinos in the NuMI neutrino beam

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    We report constraints on muon antineutrino oscillation parameters that were obtained by using the two MINOS detectors to measure the 7% antineutrino component of the NuMI neutrino beam. In the Far Detector, we select 130 events in the charged-current muon antineutrino sample, compared to a prediction of 136.4 +/- 11.7(stat) ^{+10.2}_{-8.9}(syst) events under the assumption |dm2bar|=2.32x10^-3 eV^2, snthetabar=1.0. A fit to the two-flavor oscillation approximation constrains |dm2bar|<3.37x10^-3 eV^2 at the 90% confidence level with snthetabar=1.0

    The relationship between auroral hiss at high altitudes over the polar caps and the substorm dynamics of aurora

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    Strong variations of intensity and cutoff frequency of the auroral hiss were observed by INTERBALL-2 and POLAR satellites at high altitudes, poleward from the auroral oval. The hiss intensifications are correlated with the auroral activations during substorms and/or pseudo-breakups. The low cutoff frequency of auroral hiss increases with the distance between the aurora and the satellite footprint. Multicomponent wave measurements of the hiss emissions on board the POLAR spacecraft show that the horizontal component of the Poynting flux of auroral hiss changes its direction in good accordance with longitudinal displacements of the bright auroras. The vertical component of the Poynting flux is directed upward from the aurora region, indicating that hiss could be generated by upgoing electron beams. This relationship between hiss and the aurora dynamics means that the upgoing electron beams are closely related to downgoing electron beams which produce the aurora. During the auroral activations the upgoing and downgoing beams move and change their intensities simultaneously.<br><br> <b>Keywords.</b> Magnetospheric physics (Auroral phenomena; Plasma waves and instabilities; Storms and substorms

    Radio emission of extensive air shower at CODALEMA: Polarization of the radio emission along the v*B vector

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    Cosmic rays extensive air showers (EAS) are associated with transient radio emission, which could provide an efficient new detection method of high energy cosmic rays, combining a calorimetric measurement with a high duty cycle. The CODALEMA experiment, installed at the Radio Observatory in Nancay, France, is investigating this phenomenon in the 10^17 eV region. One challenging point is the understanding of the radio emission mechanism. A first observation indicating a linear relation between the electric field produced and the cross product of the shower axis with the geomagnetic field direction has been presented (B. Revenu, this conference). We will present here other strong evidences for this linear relationship, and some hints on its physical origin.Comment: Contribution to the 31st International Cosmic Ray Conference, Lodz, Poland, July 2009. 4 pages, 8 figures. v2: Typo fixed, arxiv references adde

    Functional and symptom impact of trametinib versus chemotherapy in BRAF V600E advanced or metastatic melanoma: quality-of-life analyses of the METRIC study

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    We report the first quality-of-life assessment of a MEK inhibitor in metastatic melanoma from a phase III study. Trametinib prolonged progression-free survival and improved overall survival versus chemotherapy in patients with BRAF V600 mutation-positive melanoma. Less functional impairment, smaller declines in health status, and less exacerbation of symptoms were observed with trametini
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