281 research outputs found

    Deuteron-deuteron collision at 160 MeV

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    The experiment was carried out using BINA detector at KVI in Groningen. For the first time an extensive data analysis of the data collected in back part of the detector is presented, where a clusterization method is utilized for angular and energy information. We also present differential cross-sections for the (dd\rightarrowdpn) breakup reaction within \textit{dp} quasi-free scattering limit and their comparison with first calculations based on Single Scattering Approximation (SSA) approach.Comment: 6 pages, 4 figures, presented at Jagiellonian Symposium 2015 in Krakow, PhD wor

    Polarity determination in ZnSe nanowires by HAADF STEM

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    High angle annular dark field scanning transmission electron microscopy is used to analyze the polarity of ZnSe nanowires grown, by molecular beam epitaxy, on GaAs substrates. The experimental results are compared to simulated images in order to verify possible experimental artefacts. In this work we show that for this type of nano-objects, a residual tilt of the specimen below 15 mrad, away from the crystallographic zone axis does not impair the interpretation of the experimental images

    Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens

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    <p>Abstract</p> <p>Background</p> <p>The present study was conducted to investigate the effects of dietary plant-derived phytonutrients, carvacrol, cinnamaldehyde and Capsicum oleoresin, on the translational regulation of genes associated with immunology, physiology and metabolism using high-throughput microarray analysis and <it>in vivo</it> disease challenge model of avian coccidiosis.</p> <p>Methods</p> <p>In this study, we used nutrigenomics technology to investigate the molecular and genetic mechanisms of dietary modulation of host innate immunity and metabolism by three phytonutrients. To validate their immunomodulatory effects in a disease model, young broiler chickens fed a standard diet supplemented with three phytochemicals (carvacrol, cinnamaldehyde, and Capsicum oleoresin) from one day post-hatch were orally challenged with <it>E. acervulina</it>. The body weight gain and fecal oocyst production were used to evaluate coccidiosis disease parameters.</p> <p>Results</p> <p>Analysis of global gene expression profiles of intestinal tissues from phytonutrient-fed birds indicated that Capsicum oleoresin induced the most gene changes compared to the control group where many of these genes were associated with those of metabolism and immunity. The most reliable network induced by dietary cinnamaldehyde treatment was related with the functions of antigen presentation, humoral immune response, and inflammatory disease. Furthermore, dietary supplementation with these phytonutrients significantly protected broiler chickens against live coccidiosis challenge infection based on body weight and parasite fecundity.</p> <p>Conclusions</p> <p>The results of this study provide clear evidence to support the idea that plant-derived phytochemicals possess immune-enhancing properties in chickens and these new findings create a new possibility to develop effective drug-free alternative strategies for disease control for poultry infectious diseases.</p

    ALBA HIGH VOLTAGE SPLITTER -POWER DISTRIBUTION TO ION PUMPS

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    Abstract High Voltage Splitter (HVS) is an equipment designed in Alba that allows a high voltage (HV) distribution (up to +7kV) from one ion pump controller up to eight ion pumps. Using it, the total number of high voltage power supplies needed in Alba&apos;s vacuum installation has decreased significantly. The current drawn by each splitter channel is measured independently inside a range from 10nA up to 10mA with 5% accuracy, those measurements are a base for vacuum pressure calculations. A relation, current-pressure depends mostly on the ion pump type, so different tools providing the full calibration flexibility have been implemented. Splitter settings, status and recorded data are accessible over a 10/100 Base-T Ethernet network, none the less a local (manual) control was implemented mostly for service purposes. The device supports also additional functions as a HV cable interlock, pressure interlock output cooperating with the facility&apos;s Equipment Protection System (EPS, ref: [1]), programmable pressure warnings/alarms and automatic calibration process based on an external current source. This paper describes the project, functionality, implementation, installation and operation as a part of the vacuum system at Alba

    H2S biosynthesis and catabolism: new insights from molecular studies

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    Hydrogen sulfide (H2S) has profound biological effects within living organisms and is now increasingly being considered alongside other gaseous signalling molecules, such as nitric oxide (NO) and carbon monoxide (CO). Conventional use of pharmacological and molecular approaches has spawned a rapidly growing research field that has identified H2S as playing a functional role in cell-signalling and post-translational modifications. Recently, a number of laboratories have reported the use of siRNA methodologies and genetic mouse models to mimic the loss of function of genes involved in the biosynthesis and degradation of H2S within tissues. Studies utilising these systems are revealing new insights into the biology of H2S within the cardiovascular system, inflammatory disease, and in cell signalling. In light of this work, the current review will describe recent advances in H2S research made possible by the use of molecular approaches and genetic mouse models with perturbed capacities to generate or detoxify physiological levels of H2S gas within tissue
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