1,605 research outputs found

    Trace semantics for polymorphic references

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    Research supported by the Engineering and Physical Sciences Research Council (EP/L022478/1) and the Royal Academy of Engineering

    Lymphoepithelial carcinoma in the maxillary sinus: a case report.

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    INTRODUCTION: Lymphoepithelial carcinoma of the maxillary sinus is a very rare malignancy and it can be difficult to make a pre-operative diagnosis. CASE PRESENTATION: A 72-year-old Caucasian woman presented to our facility with an isolated right-side epistaxis that had been present for three months, with the results of a computed tomography scan showing a soft tissue mass in the right maxillary sinus with an impacted tooth. The results of a transnasal endoscopic biopsy were compatible with a lymphoepithelial carcinoma, following which our patient underwent a radical excision of the mass. The final histology results revealed lymphoepithelial carcinoma of the maxillary sinus with negative assays for Epstein-Barr virus. Our patient was given post-operative external radiotherapy and has remained disease-free at three-year follow-up. CONCLUSIONS: This report details the diagnosis and management of a case of lymphoepithelial carcinoma of the maxillary sinus, which is a very rare malignant tumor with very little mention in the literature. Only a strong suspicion with systematic use of various patho-immunological tests helps to arrive at a definitive diagnosis by excluding other better-known tumors

    Facile synthesis of metal-organic framework films via in situ seeding of nanoparticles

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    A facile in situ nanoparticle seeding method is reported to prepare MIL-101(Cr) films on alumina supports. The in situ seeding of MIL-101(Cr) nanoparticles was promoted by use of dimethylacetamide (DMA). The generality of this approach is further demonstrated for Cu 3(btc) 2 films by using a (poly)acrylate promoter

    Matrix for specific detection of alkaloids by MALDI-​TOF mass spectrometry

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    The présent invention relates to a novel bithiophenic matrix for spécifie détection of alkaloids by MALDI-TOF mass spectrometr

    Knowledge, attitude and opinion of drug misuse and abuse by pharmacy students: a cross-sectional study in Jordan

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    Purpose: To assess the knowledge, attitude and opinion of final-year undergraduate and postgraduate pharmacy students regarding inappropriate drug use in a university campus, Amman, Jordan.Methods: A cross-sectional survey using a self-completed validated anonymous questionnaire that consisted of two parts was adopted. The first part of the questionnaire pertained to respondents’ demographic details, education level and any experience they might have had with drug misuse or abuse. The second part described students' knowledge, attitude and practice regarding the identification, prevention and management of drug misuse and abuse.Results: A total number of 198 pharmacy students filled the questionnaire (N = 131 undergraduate, and N = 67 postgraduate students). A majority of the students strongly agreed/agreed that all pharmacy staff must be trained on recognizing drug abusers (92.0 %), informed of the kinds of drugs abused in the local area of the pharmacy (93.4 %) and trained on methods of dealing with drug abusers (92.6 %).Conclusion: There is a need to implement a well-structured training on the identification, prevention and management of prescription and OTC drug misuse and abuse in undergraduate pharmacy curricula in Jordan. Modules should be updated regularly and tailored to meet the needs of pharmacy practice

    An efficient data Parallelization of the Radix-23 (Carbon) FFT on GPU/CPU

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    Solving Complex Problem that is coupled with intensive workloads; necessities the access to a massively parallel computational power. Up to date, Graphic Processing Units (GPUs) are the only architecture that could handle the most complex computationally intensive workloads. In the light of this rapid-growing advancement in computational technologies, this paper will propose a high-performance parallel radix-23 FFT suitable for such GPU and CPU systems. The proposed algorithm could reduce the computational complexity by a factor that tends to reach pr if implemented in parallel (pr is the number of cores/threads) plus the combination phase to complete the required FFT

    Insulin Sensitivity and Secretion in Arab Americans with Glucose Intolerance

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    Background: This study examined the pathophysiological abnormalities in Arab Americans with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT). Subjects and Methods: Homeostasis model assessment of insulin resistance (HOMA-IR), homeostasis model assessment of insulin secretion (HOMA-%?), and the Matsuda Insulin Sensitivity Index composite (ISIcomposite) were calculated from the fasting and stimulated glucose and insulin concentrations measured during the oral glucose tolerance test in a population-based, representative, cross-sectional sample of randomly selected Arab Americans. Results: In total, 497 individuals (42±14 years old; 40% males; body mass index [BMI], 29±6?kg/m2) were studied. Multivariate linear regression models were performed to compare HOMA-IR, HOMA-%?, and ISIcomposite among individuals with normal glucose tolerance (NGT) (n=191) versus isolated IFG (n=136), isolated IGT (n=22), combined IFG/IGT (n=43), and diabetes (n=105). Compared with individuals with NGT (2.9±1.6), HOMA-IR progressively increased in individuals with isolated IFG (4.8±2.7, P<0.001), combined IFG/IGT (6.0±4.3, P<0.001), and diabetes (9.7±8.3, P<0.001) but not in those with isolated IGT (3.0±1.7, P=0.87). After adjustment for sex and BMI, these associations remained unchanged. Whole-body insulin sensitivity as measured by ISIcomposite was significantly lower in individuals with isolated IFG (3.9±2.3, P<0.001), isolated IGT (2.8±1.5, P<0.001), combined IFG/IGT (1.9±1.1, P<0.001), and diabetes (1.6±1.1, P<0.001) compared with those with NGT (6.1±3.5). HOMA-%? was significantly lower in diabetes (113.7±124.9, P<0.001) compared with NGT (161.3±92.0). After adjustment for age, sex, and BMI, isolated IFG (146.6±80.2) was also significantly associated with a decline in HOMA-%? relative to NGT (P=0.005). Conclusions: This study suggests that differences in the underlying metabolic defects leading to diabetes in Arab Americans with IFG and/or IGT exist and may require different strategies for the prevention of diabetes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140352/1/dia.2013.0045.pd

    Spin-orbit coupling and the conservation of angular momentum

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    In nonrelativistic quantum mechanics, the total (i.e. orbital plus spin) angular momentum of a charged particle with spin that moves in a Coulomb plus spin-orbit-coupling potential is conserved. In a classical nonrelativistic treatment of this problem, in which the Lagrange equations determine the orbital motion and the Thomas equation yields the rate of change of the spin, the particle's total angular momentum in which the orbital angular momentum is defined in terms of the kinetic momentum is generally not conserved. However, a generalized total angular momentum, in which the orbital part is defined in terms of the canonical momentum, is conserved. This illustrates the fact that the quantum-mechanical operator of momentum corresponds to the canonical momentum of classical mechanics.Comment: 10 pages, as published by Eur. J. Phy

    The JM-Filter to detect specific frequency in monitored signal

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    The Discrete Fourier Transform (DFT) is a mathematical procedure that stands at the center of the processing inside a digital signal processor. It has been widely known and argued in relevant literature that the Fast Fourier Transform (FFT) is useless in detecting specific frequencies in a monitored signal of length N because most of the computed results are ignored. In this paper, we present an efficient FFT-based method to detect specific frequencies in a monitored signal, which will then be compared to the most frequently used method which is the recursive Goertzel algorithm that detects and analyses one selectable frequency component from a discrete signal. The proposed JM-Filter algorithm presents a reduction of iterations compared to the first and second order Goertzel algorithm by a factor of r, where r represents the radix of the JM-Filter. The obtained results are significant in terms of computational reduction and accuracy in fixed-point implementation. Gains of 15 dB and 19 dB in signal to quantization noise ratio (SQNR) were respectively observed for the proposed first and second order radix-8 JM-Filter in comparison to Goertzel algorithm
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