15,448 research outputs found

    The generic task toolset: High level languages for the construction of planning and problem solving systems

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    The current generation of languages for the construction of knowledge-based systems as being at too low a level of abstraction is criticized, and the need for higher level languages for building problem solving systems is advanced. A notion of generic information processing tasks in knowledge-based problem solving is introduced. A toolset which can be used to build expert systems in a way that enhances intelligibility and productivity in knowledge acquistion and system construction is described. The power of these ideas is illustrated by paying special attention to a high level language called DSPL. A description is given of how it was used in the construction of a system called MPA, which assists with planning in the domain of offensive counter air missions

    Cloud and ice in the planetary scale circulation and in climate

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    The roles of the cryosphere, and of cloud-radiative interactions are investigated. The effects clouds and ice have in the climate system are examined. The cloud radiation research attempts explain the modes of interaction (feedback) between raditive transfer, cloud formation, and atmospheric dynamics. The role of sea ice in weather and climate is also discussed. Models are used to describe the ice and atmospheric dynamics under study

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    EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential

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    Crosstalk between mesenchymal stromal cells (MSCs) and hematopoietic stem cells (HSCs) is essential for hematopoietic homeostasis and lineage output. Here, we investigate how transcriptional changes in bone marrow (BM) MSCs result in long-lasting effects on HSCs. Single-cell analysis of Cxcl12-abundant reticular (CAR) cells and PDGFRα+Sca1+ (PαS) cells revealed an extensive cellular heterogeneity but uniform expression of the transcription factor gene Ebf1. Conditional deletion of Ebf1 in these MSCs altered their cellular composition, chromatin structure and gene expression profiles, including the reduced expression of adhesion-related genes. Functionally, the stromal-specific Ebf1 inactivation results in impaired adhesion of HSCs, leading to reduced quiescence and diminished myeloid output. Most notably, HSCs residing in the Ebf1-deficient niche underwent changes in their cellular composition and chromatin structure that persist in serial transplantations. Thus, genetic alterations in the BM niche lead to long-term functional changes of HSCs

    Electromagnetics from a quasistatic perspective

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    Quasistatics is introduced so that it fits smoothly into the standard textbook presentation of electrodynamics. The usual path from statics to general electrodynamics is rather short and surprisingly simple. A closer look reveals however that it is not without confusing issues as has been illustrated by many contributions to this Journal. Quasistatic theory is conceptually useful by providing an intermediate level in between statics and the full set of Maxwell's equations. Quasistatics is easier than general electrodynamics and in some ways more similar to statics. It is however, in terms of interesting physics and important applications, far richer than statics. Quasistatics is much used in electromagnetic modeling, an activity that today is possible on a PC and which also has great pedagogical potential. The use of electromagnetic simulations in teaching gives additional support for the importance of quasistatics. This activity may also motivate some change of focus in the presentation of basic electrodynamics

    Precarious Security

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    Superconducting and structural properties of plasma sprayed YBaCuO layers deposited on metallic substrates

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    The properties of plasma sprayed Y-Ba-Cu-O coatings deposited on metallic substrates are studied. Stainless steel, nickel steels and pure nickel are used as substrate. Y-Ba-Cu-O deposited on stainless steel and nickel steel reacts with the substrate. This interaction can be suppressed by using an yttria-stabilized zirconia (YsZ) diffusion barrier. However, after heat treatment the Y-Ba-Cu-O layers on YsZ show cracks perpendicular to the surface. As a result the critical current density is very low. The best results are obtained for Y-Ba-Cu-O deposited on pure nickel; here no cracks perpendicular to the surface are observed. The critical current increases with the anneal temperature but annealing for longer than 10 h does not seem to improve the superconducting properties any further

    Technique for Obtaining Vertical Profiles of Backscattering and Extinction Cross Sections Using Slant Path Lidar Measurements

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    A method is presented for solving for vertical profiles of atmospheric particulate extinction and backscattering cross-sections utilizing monostatic lidar slant path measurements. The method is an extension of work by Fernald. It is shown that the number of assumptions necessary for an iterative solution of extinction and backscattering cross sections can be reduced if lidar slant path measurements are used to solve directly for optical depths. The technique is useful only if sufficiently accurate lidar measurements are available. With highly accurate measurements it is also possible to solve directly for extinction cross sections without an iterative solution of a transcendental equation if the proper reduction scheme is used. The required accuracy is discussed and results showing the effect of errors are presented
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