856 research outputs found
Traffic jams and intermittent flows in microfluidic networks
We investigate both experimentally and theoretically the traffic of particles
flowing in microfluidic obstacle networks. We show that the traffic dynamics is
a non-linear process: the particle current does not scale with the particle
density even in the dilute limit where no particle collision occurs. We
demonstrate that this non-linear behavior stems from long range hydrodynamic
interactions. Importantly, we also establish that there exists a maximal
current above which no stationary particle flow can be sustained. For higher
current values, intermittent traffic jams form thereby inducing the ejection of
the particles from the initial path and the subsequent invasion of the network.
Eventually, we put our findings in the broader context of the transport
proccesses of driven particles in low dimension
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Basal rot of narcissus : understanding pathogenicity in fusarium oxysporum f. sp. narcissi
Fusarium oxysporum is a globally distributed soilborne fungal pathogen causing root rots, bulb rots, crown rots and vascular wilts on a range of horticultural plants. Pathogenic F. oxysporum isolates are highly host specific and are classified as formae speciales. Narcissus is an important ornamental crop and both the quality and yield of flowers and bulbs can be severely affected by a basal rot caused by F. oxysporum f. sp. narcissi (FON); 154 Fusarium isolates were obtained from different locations and Narcissus cultivars in the United Kingdom, representing a valuable resource. A subset of 30 F. oxysporum isolates were all found to be pathogenic and were therefore identified as FON. Molecular characterisation of isolates through sequencing of three housekeeping genes, suggested a monophyletic origin with little divergence. PCR detection of 14 Secreted in Xylem (SIX) genes, previously shown to be associated with pathogenicity in other F. oxysporum f. spp., revealed different complements of SIX7, SIX9, SIX10, SIX12 and SIX13 within FON isolates which may suggest a race structure. SIX gene sequences were unique to FON and SIX10 was present in all isolates, allowing for molecular identification of FON for the first time. The genome of a highly pathogenic isolate was sequenced and lineage specific (LS) regions identified which harboured putative effectors including the SIX genes. Real-time RT-PCR, showed that SIX genes and selected putative effectors were expressed in planta with many significantly upregulated during infection. This is the first study to characterise molecular variation in FON and provide an analysis of the FON genome. Identification of expressed genes potentially associated with virulence provides the basis for future functional studies and new targets for molecular diagnostics
Influence of flow confinement on the drag force on a static cylinder
The influence of confinement on the drag force on a static cylinder in a
viscous flow inside a rectangular slit of aperture has been investigated
from experimental measurements and numerical simulations. At low enough
Reynolds numbers, varies linearly with the mean velocity and the viscosity,
allowing for the precise determination of drag coefficients and
corresponding respectively to a mean flow parallel and
perpendicular to the cylinder length . In the parallel configuration, the
variation of with the normalized diameter of the
cylinder is close to that for a 2D flow invariant in the direction of the
cylinder axis and does not diverge when . The variation of
with the distance from the midplane of the model reflects the
parabolic Poiseuille profile between the plates for while it
remains almost constant for . In the perpendicular configuration,
the value of is close to that corresponding to a 2D system
only if and/or if the clearance between the ends of the cylinder
and the side walls is very small: in that latter case,
diverges as due to the blockage of the flow. In other cases, the
side flow between the ends of the cylinder and the side walls plays an
important part to reduce : a full 3D description of the flow is
needed to account for these effects
Experimental and numerical investigations of flow structure and momentum transport in a turbulent buoyancy-driven flow inside a tilted tube.
Buoyancy-driven turbulent mixing of fluids of slightly different densities [At = ÎÏ/(2ăÏă) = 1.15Ă10â2] in a long circular tube tilted at an angle Ξ = 15° from the vertical is studied at the local scale, both experimentally from particle image velocimetry and laser induced fluorescence measurements in the vertical diametrical plane and numerically throughout the tube using direct numerical simulation. In a given cross section of the tube, the axial mean velocity and the mean concentration both vary linearly with the crosswise distance z from the tube axis in the central 70% of the diameter. A small crosswise velocity component is detected in the measurement plane and is found to result from a four-cell mean secondary flow associated with a nonzero streamwise component of the vorticity. In the central region of the tube cross section, the intensities of the three turbulent velocity fluctuations are found to be strongly different, that of the streamwise fluctuation being more than twice larger than that of the spanwise fluctuation which itself is about 50% larger than that of the crosswise fluctuation. This marked anisotropy indicates that the turbulent structure is close to that observed in homogeneous turbulent shear flows. Still in the central region, the turbulent shear stress dominates over the viscous stress and reaches a maximum on the tube axis. Its crosswise variation is approximately accounted for by a mixing length whose value is about one-tenth of the tube diameter. The momentum exchange in the core of the cross section takes place between its lower and higher density parts and there is no net momentum exchange between the core and the near-wall regions. A sizable part of this transfer is due both to the mean secondary flow and to the spanwise turbulent shear stress. Near-wall regions located beyond the location of the extrema of the axial velocity (|z|âł0.36âd) are dominated by viscous stresses which transfer momentum toward (from) the wall near the top (bottom) of the tube
Measuring fast electron spectra and laser absorption in relativistic laser-solid interactions using differential bremsstrahlung photon detectors
A photon detector suitable for the measurement of bremsstrahlung spectra
generated in relativistically-intense laser-solid interactions is described.
The Monte Carlo techniques used to back-out the fast electron spectrum and
laser energy absorbed into fast electrons are detailed. A
relativistically-intense laser-solid experiment using frequency doubled laser
light is used to demonstrate the effective operation of the detector. The
experimental data was interpreted using the 3-spatial-dimension Monte Carlo
code MCNPX (Pelowitz 2008), and the fast electron temperature found to be 125
keV
PCN3 EFFECTIVENESS OF BORTEZOMIB IN MULTIPLE MYELOMA: PRELIMINARY RESULTS FROM AN INTERNATIONAL ELECTRONIC OBSERVATIONAL STUDY
Draft genome sequence of an onion basal rot isolate of Fusarium proliferatum
Fusarium proliferatum is a component of the onion basal rot disease complex. We present an annotated F. proliferatum draft genome sequence, totaling 45.8 Mb in size, assembled into 597 contigs, with a predicted 15,418 genes. The genome contains 58 secondary metabolite clusters and homologs of the Fusarium oxysporum effector SIX2
Spin splitting in a polarized quasi-two-dimensional exciton gas
We have observed a large spin splitting between "spin" and
heavy-hole excitons, having unbalanced populations, in undoped GaAs/AlAs
quantum wells in the absence of any external magnetic field. Time-resolved
photoluminescence spectroscopy, under excitation with circularly polarized
light, reveals that, for high excitonic density and short times after the
pulsed excitation, the emission from majority excitons lies above that of
minority ones. The amount of the splitting, which can be as large as 50% of the
binding energy, increases with excitonic density and presents a time evolution
closely connected with the degree of polarization of the luminescence. Our
results are interpreted on the light of a recently developed model, which shows
that, while intra-excitonic exchange interaction is responsible for the spin
relaxation processes, exciton-exciton interaction produces a breaking of the
spin degeneracy in two-dimensional semiconductors.Comment: Revtex, four pages; four figures, postscript file Accepted for
publication in Physical Review B (Rapid Commun.
The significance of seniority for women managersâ interpretations of organizational restructuring
This paper examines the impact of restructuring within the transport and logistics sector on women managers working at senior and less senior (middle/junior management) levels of the organization. The majority of women experienced increased performance pressures and heavier workloads as well as an increase in working hours. At the same time, there were pressures to work at home (i.e. week-ends and evenings) and reduced opportunities to work from home (i.e. during normal office hours). Management level emerged as an important factor in how these changes were interpreted. Senior managers perceived more positive outcomes in terms of increased motivation and loyalty. Despite a longer working week, they were less likely to report low morale as an outcome from long hours. In fact, irrespective of management level, women working shorter hours were more likely to report low morale as an outcome. Results are discussed in relation to literature on restructuring and careers, in terms of perceptual framing and in relation to different levels of investment in the organization
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