Manufacturing advisory service in the East Midlands – historical evaluation

A report on the longitudinal evaluation of the Manufacturing Advisory Service (MAS) covering the period from its establishment in 2005. The evaluation looks at net economic impact and the appropriateness of the design and delivery of the service, in addition to identifying any areas for improvement

Spatial mapping of hepatitis C prevalence in recent injecting drug users in contact with services.

In developed countries the majority of hepatitis C virus (HCV) infections occur in injecting drug users (IDUs) with prevalence in IDUs often high, but with wide geographical differences within countries. Estimates of local prevalence are needed for planning services for IDUs, but it is not practical to conduct HCV seroprevalence surveys in all areas. In this study survey data from IDUs attending specialist services were collected in 52/149 sites in England between 2006 and 2008. Spatially correlated random-effects models were used to estimate HCV prevalence for all sites, using auxiliary data to aid prediction. Estimates ranged from 14% to 82%, with larger cities, London and the North West having the highest HCV prevalence. The methods used generated robust estimates for each area, with a well-identified spatial pattern that improved predictions. Such models may be of use in other areas of study where surveillance data are sparse

Oculomotor examination of the weapon focus effect: does a gun automatically engage visual attention?

A person is less likely to be accurately remembered if they appear in a visual scene with a gun, a result that has been termed the weapon focus effect (WFE). Explanations of the WFE argue that weapons engage attention because they are unusual and/or threatening, which causes encoding deficits for the other items in the visual scene. Previous WFE research has always embedded the weapon and nonweapon objects within a larger context that provides information about an actor's intention to use the object. As such, it is currently unknown whether a gun automatically engages attention to a greater extent than other objects independent of the context in which it is presente

Evaluation of business link in the East Midlands

An evaluation of activities delivered through the Business Link service in the East Midlands region between April 2007 and March 2010, focussing on: net economic impacts; Strategic Added Value (SAV); and potential lessons for the future delivery of business support services

Fast gates for ion traps by splitting laser pulses

We present a fast phase gate scheme that is experimentally achievable and has an operation time more than two orders of magnitude faster than current experimental schemes for low numbers of pulses. The gate time improves with the number of pulses following an inverse power law. Unlike implemented schemes which excite precise motional sidebands, thus limiting the gate timescale, our scheme excites multiple motional states using discrete ultra-fast pulses. We use beam-splitters to divide pulses into smaller components to overcome limitations due to the finite laser pulse repetition rate. This provides gate times faster than proposed theoretical schemes when we optimise a practical setup.Comment: 20 pages, 8 figure

Trapped ion scaling with pulsed fast gates

Fast entangling gates for trapped ions offer vastly improved gate operation times relative to implemented gates, as well as approaches to trap scaling. Gates on neighbouring ions only involve local ions when performed sufficiently fast, and we find that even a fast gate between distant ions with few degrees of freedom restores all the motional modes given more stringent gate speed conditions. We compare pulsed fast gate schemes, defined by a timescale faster than the trap period, and find that our proposed scheme has less stringent requirements on laser repetition rate for achieving arbitrary gate time targets and infidelities well below $10^{-4}$. By extending gate schemes to ion crystals, we explore the effect of ion number on gate fidelity for coupling neighbouring pairs of ions in large crystals. Inter-ion distance determines the gate time, and a factor of five increase in repetition rate, or correspondingly the laser power, reduces the infidelity by almost two orders of magnitude. We also apply our fast gate scheme to entangle the first and last ions in a crystal. As the number of ions in the crystal increases, significant increases in the laser power are required to provide the short gate times corresponding to fidelity above 0.99.Comment: 29 pages, 10 figure

Long-range coupling of silicon photonic waveguides using lateral leakage and adiabatic passage

We present a new approach to long range coupling based on a combination of adiabatic passage and lateral leakage in thin shallow ridge waveguides on a silicon photonic platform. The approach enables transport of light between two isolated waveguides through a mode of the silicon slab that acts as an optical bus. Due to the nature of the adiabatic protocol, the bus mode has minimal population and the transport is highly robust. We prove the concept and examine the robustness of this approach using rigorous modelling. We further demonstrate the utility of the approach by coupling power between two waveguides whilst bypassing an intermediate waveguide. This concept could form the basis of a new interconnect technology for silicon integrated photonic chips

Outcoupling from a Bose-Einstein condensate with squeezed light to produce entangled atom laser beams

We examine the properties of an atom laser produced by outcoupling from a Bose-Einstein condensate with squeezed light. We model the multimode dynamics of the output field and show that a significant amount of squeezing can be transfered from an optical mode to a propagating atom laser beam. We use this to demonstrate that two-mode squeezing can be used to produce twin atom laser beams with continuous variable entanglement in amplitude and phase.Comment: 11 pages, 14 figure

Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo

In contrast to the results of previous in vitro studies, experimental infection of calves with noncytopathic bovine viral diarrhea virus (ncpBVDV) was found to induce strong alpha/beta and gamma interferon responses in gnotobiotic animals. These responses were associated with depressed levels of transforming growth factor β (TGF-β) in serum. The results of this study indicate that the immunosuppression caused by ncpBVDV is not associated with low interferon responses or elevated levels of TGF-β