Pseudospin symmetry and its approximation in real nuclei

The origin of pseudospin symmetry and its broken in real nuclei are discussed in the relativistic mean field theory. In the exact pseudospin symmetry, even the usual intruder orbits have degenerate partners. In real nuclei, pseudospin symmetry is approximate, and the partners of the usual intruder orbits will disappear. The difference is mainly due to the pseudo spin-orbit potential and the transition between them is discussed in details. The contribution of pseudospin-orbit potential for intruder orbits is quite large, compared with that for pseudospin doublets. The disappearance of the pseudospin partner for the intruder orbit can be understood from the properties of its wave function.Comment: 10 pages, 3 figure

Addition of T2-Guided Optical Tomography Improves Noncontrast Breast Magnetic Resonance Imaging Diagnosis.

BACKGROUND: While dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) is recognized as the most sensitive examination for breast cancer detection, it has a substantial false positive rate and gadolinium (Gd) contrast agents are not universally well tolerated. As a result, alternatives to diagnosing breast cancer based on endogenous contrast are of growing interest. In this study, endogenous near-infrared spectral tomography (NIRST) guided by T2 MRI was evaluated to explore whether the combined imaging modality, which does not require contrast injection or involve ionizing radiation, can achieve acceptable diagnostic performance. METHODS: Twenty-four subjects-16 with pathologically confirmed malignancy and 8 with benign abnormalities-were simultaneously imaged with MRI and NIRST prior to definitive pathological diagnosis. MRIs were evaluated independently by three breast radiologists blinded to the pathological results. Optical image reconstructions were constrained by grayscale values in the T2 MRI. MRI and NIRST images were used, alone and in combination, to estimate the diagnostic performance of the data. Outcomes were compared to DCE results. RESULTS: Sensitivity, specificity, accuracy, and area under the curve (AUC) of noncontrast MRI when combined with T2-guided NIRST were 94%, 100%, 96%, and 0.95, respectively, whereas these values were 94%, 63%, 88%, and 0.81 for DCE MRI alone, and 88%, 88%, 88%, and 0.94 when DCE-guided NIRST was added. CONCLUSION: In this study, the overall accuracy of imaging diagnosis improved to 96% when T2-guided NIRST was added to noncontrast MRI alone, relative to 88% for DCE MRI, suggesting that similar or better diagnostic accuracy can be achieved without requiring a contrast agent

Hybrid nature of 0846+51W1: a BL Lac object with a narrow line Seyfert 1 nucleus

We have found a NLS1 nucleus in the extensively studied eruptive BL Lac, 0846+51W1, out of a large sample of NLS1 compiled from the spectroscopic dataset of SDSS DR1. Its optical spectrum can be well decomposed into three components, a power law component from the relativistic jet, a stellar component from the host galaxy, and a component from a typical NLS1 nucleus. The emission line properties of 0846+51W1, FWHM(Hbeta) ~ 1710 km s^-1 and [OIII]5007/Hbeta ~ 0.32 when it was in faint state, fulfil the conventional definition of NLS1. Strong FeII emission is detected in the SDSS spectrum, which is also typical of NLS1s. We try to estimate its central black hole mass using various techniques and find that 0846+51W1 is very likely emitting at a few times 10% L_Edd. We speculate that Seyfert-like nuclei, including NLS1s, might be concealed in a significant fraction of BL Lacs but have not been sufficiently explored due to the fact that, by definition, the optical-UV continuum of such kind of objects are often overwhelmed by the synchrotron emission.Comment: ChJAA accepte

Effect of Control Strategies on Prevalence, Incidence and Re-infection of Clonorchiasis in Endemic Areas of China

Clonorchiasis is a liver fluke disease prevalent in East Asia, which is transmitted to humans mainly by eating raw freshwater fish. It induces various complications in the liver or bile duct including cholelithiasis, cholecystitis, cholangitis, and cirrhosis. Clonorchis sinensis has been known to cause cholangiocarcinoma, and is still a major health problem in endemic areas. People in endemic areas are repeatedly infected with C. sinensis, as they continue to consume raw freshwater fish in spite of control activities and availability of a highly effective drug, praziquantel. Reservoir hosts such as cats, dogs, and pigs supply eggs continuously to the environment and act as a source of infection. The present study analyzed the data produced by the Korea-China collaborative project for helminthiasis control in China during 2001–2004 to find out effective chemotherapeutic control strategies with praziquantel in endemic areas and to evaluate their effects on the transmission of C. sinensis infection by repeated mass or selective treatment. The four-year control trial found that repeated treatment is essential to the effective reduction of prevalence and infection intensity in heavily endemic areas. Mass chemotherapy is more effective than selective treatment, and more repeated treatments produce better outcomes in clonorchiasis control. Health education to change the habit of consuming raw or undercooked fish is an important and practical measure to prevent and reduce human infections in endemic areas. Together with chemotherapy, health education could be highly effective and produce sustainable effects in clonorchiasis control. Treatment of reservoirs, if applicable, will contribute to reduce the source of infection

Complete mitochondrial genomes of Taenia multiceps, T. hydatigena and T. pisiformis: additional molecular markers for a tapeworm genus of human and animal health significance

<p>Abstract</p> <p>Background</p> <p>Mitochondrial genomes provide a rich source of molecular variation of proven and widespread utility in molecular ecology, population genetics and evolutionary biology. The tapeworm genus <it>Taenia </it>includes a diversity of tapeworm parasites of significant human and veterinary importance. Here we add complete sequences of the mt genomes of <it>T. multiceps</it>, <it>T. hydatigena </it>and <it>T. pisiformis</it>, to a data set of 4 published mtDNAs in the same genus. Seven complete mt genomes of <it>Taenia </it>species are used to compare and contrast variation within and between genomes in the genus, to estimate a phylogeny for the genus, and to develop novel molecular markers as part of an extended mitochondrial toolkit.</p> <p>Results</p> <p>The complete circular mtDNAs of <it>T. multiceps</it>, <it>T. hydatigena </it>and <it>T. pisiformis </it>were 13,693, 13,492 and 13,387 bp in size respectively, comprising the usual complement of flatworm genes. Start and stop codons of protein coding genes included those found commonly amongst other platyhelminth mt genomes, but the much rarer initiation codon GTT was inferred for the gene <it>atp</it>6 in <it>T. pisiformis</it>. Phylogenetic analysis of mtDNAs offered novel estimates of the interrelationships of <it>Taenia</it>. Sliding window analyses showed <it>nad</it>6, <it>nad</it>5, <it>atp</it>6, <it>nad</it>3 and <it>nad</it>2 are amongst the most variable of genes per unit length, with the highest peaks in nucleotide diversity found in <it>nad</it>5. New primer pairs capable of amplifying fragments of variable DNA in <it>nad</it>1, <it>rrn</it>S and <it>nad</it>5 genes were designed <it>in silico </it>and tested as possible alternatives to existing mitochondrial markers for <it>Taenia</it>.</p> <p>Conclusions</p> <p>With the availability of complete mtDNAs of 7 <it>Taenia </it>species, we have shown that analysis of amino acids provides a robust estimate of phylogeny for the genus that differs markedly from morphological estimates or those using partial genes; with implications for understanding the evolutionary radiation of important <it>Taenia</it>. Full alignment of the nucleotides of <it>Taenia </it>mtDNAs and sliding window analysis suggests numerous alternative gene regions are likely to capture greater nucleotide variation than those currently pursued as molecular markers. New PCR primers developed from a comparative mitogenomic analysis of <it>Taenia </it>species, extend the use of mitochondrial markers for molecular ecology, population genetics and diagnostics.</p

Day-ahead industrial load forecasting for electric RTG cranes

Given the increase in international trading and the significant energy and environmental challenges in ports around the world, there is a need for a greater understanding of the energy demand behaviour at ports. The move towards electrified rubber-tyred gantry (RTG) cranes is expected to reduce gas emissions and increase energy savings compared to diesel RTG cranes but it will increase electrical energy demand. Electrical load forecasting is a key tool for understanding the energy demand which is usually applied to data with strong regularities and seasonal patterns. However, the highly volatile and stochastic behaviour of the RTG crane demand creates a substantial prediction challenge. This paper is one of the first extensive investigations into short term load forecasts for electrified RTG crane demand. Options for model inputs are investigated depending on extensive data and correlation analysis. The effect of estimation accuracy of exogenous variables on the forecast accuracy is investigated as well. The models are tested on two different RTG crane data sets that were collected from the Port of Felixstowe in the UK. The results reveal the effectiveness of the forecast models when the estimation of the number of crane moves and container gross weight are accurate

Regularized gene selection in cancer microarray meta-analysis

<p>Abstract</p> <p>Background</p> <p>In cancer studies, it is common that multiple microarray experiments are conducted to measure the same clinical outcome and expressions of the same set of genes. An important goal of such experiments is to identify a subset of genes that can potentially serve as predictive markers for cancer development and progression. Analyses of individual experiments may lead to unreliable gene selection results because of the small sample sizes. Meta analysis can be used to pool multiple experiments, increase statistical power, and achieve more reliable gene selection. The meta analysis of cancer microarray data is challenging because of the high dimensionality of gene expressions and the differences in experimental settings amongst different experiments.</p> <p>Results</p> <p>We propose a Meta Threshold Gradient Descent Regularization (MTGDR) approach for gene selection in the meta analysis of cancer microarray data. The MTGDR has many advantages over existing approaches. It allows different experiments to have different experimental settings. It can account for the joint effects of multiple genes on cancer, and it can select the same set of cancer-associated genes across multiple experiments. Simulation studies and analyses of multiple pancreatic and liver cancer experiments demonstrate the superior performance of the MTGDR.</p> <p>Conclusion</p> <p>The MTGDR provides an effective way of analyzing multiple cancer microarray studies and selecting reliable cancer-associated genes.</p

Self-Assembled 3D Flower-Like Hierarchical β-Ni(OH)2Hollow Architectures and their In Situ Thermal Conversion to NiO

Three-dimensional (3D) flower-like hierarchicalβ-Ni(OH)2hollow architectures were synthesized by a facile hydrothermal route. The as-obtained products were well characterized by XRD, SEM, TEM (HRTEM), SAED, and DSC-TGA. It was shown that the 3D flower-like hierarchicalβ-Ni(OH)2hollow architectures with a diameter of several micrometers are assembled from nanosheets with a thickness of 10–20 nm and a width of 0.5–2.5 μm. A rational mechanism of formation was proposed on the basis of a range of contrasting experiments. 3D flower-like hierarchical NiO hollow architectures with porous structure were obtained after thermal decomposition at appropriate temperatures. UV–Vis spectra reveal that the band gap of the as-synthesized NiO samples was about 3.57 eV, exhibiting obviously red shift compared with the bulk counterpart

Noether Symmetry Approach in "Cosmic Triad" Vector Field Scenario

To realize the accelerations in the early and late periods of our universe, we need to specify potentials for the dominant fields. In this paper, by using the Noether symmetry approach, we try to find suitable potentials in the "cosmic triad" vector field scenario. Because the equation of state parameter of dark energy has been constrained in the range of $-1.21\leq \omega\leq -0.89$ by observations, we derive the Noether conditions for the vector field in quintessence, phantom and quintom models, respectively. In the first two cases, constant potential solutions have been obtained. What is more, a fast decaying point-like solution with power-law potential is also found for the vector field in quintessence model. For the quintom case, we find an interesting constraint $\tilde{C}V_{p}'=-CV_{q}'$ on the field potentials, where $C$ and $\tilde{C}$ are constants related to the Noether symmetry.Comment: 15 pages, no figures, accepted by Classical and Quantum Gravity

Machine Autonomy : Definition, Approaches, Challenges and Research Gaps

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