1,500 research outputs found

    Survey to architects: challenges to inspection and diagnosis in historical residential buildings

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    Using a web query among architects (n=57), we could identify the main obstacles found in the application of inspection and diagnosis procedures in historical residential buildings.  The results revealed that these procedures are not yet uniformly applied in this built heritage and pointed out the need to develop simplified methodologies and less resource-consuming methodologies, to ensure their applicability.The authors would like to acknowledge the support granted by the Portuguese Foundation for Science and Technology (FCT), in the scope of the Doctoral Program Eco-Construction and Rehabilitation (EcoCoRe), to the PhD scholarship with the reference PD/BD/127853/2016 that was fundamental for the development of this study.info:eu-repo/semantics/publishedVersio

    Solving analytic differential equations in polynomial time over unbounded domains

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    In this paper we consider the computational complexity of solving initial-value problems de ned with analytic ordinary diferential equations (ODEs) over unbounded domains of Rn and Cn, under the Computable Analysis setting. We show that the solution can be computed in polynomial time over its maximal interval of de nition, provided it satis es a very generous bound on its growth, and that the function admits an analytic extension to the complex plane

    Probing solute distribution and acid-base behaviour in water-in-oil microemulsions by fluorescence techniques

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    The distribution and acid-base behaviour of the four solutes harmine, chromotropic acid (4,5-dihydroxynaphthalene-2,7-disulfonate, disodium salt), 2-naphthol and 5,10,15,20-tetrakis [4-trimethylammonium)phenyl]-21H,23H-porphine tetra-p-tosylate (TTMP) have been studied in water-in-oil (w/o) microemulsions using fluorescence and absorption spectroscopy. Carbon tetrachloride is a quencher of fluorescence of these compounds, and studies using this as oil phase in microemulsions show that chromotropic acid is located in the water domain, TTMP at the surfactant-water interface, while the distribution of harmine or 2-naphthol depends on the degree of protonation. Detailed studies have been made on harmine. In water/AOT/cyclohexane microemulsions the cationic form is observed up to much higher apparent pH than in aqueous solutions. An important factor is shown to be the compartmentalisation of hydroxide ions between water pools. Similar effects are observed with the other probes, and it is suggested that compartmentalisation of hydrogen or hydroxide ions is a major effect in many acid-base reactions in microemulsions. The validity of the concept of pH in microemulsions under these conditions is questioned. Fluorescence lifetime measurements are also shown to provide information on the dynamics of the processes, and demonstrate the importance of diffusion of solutes from organic solvent to the microemulsion pool. A comparison is made of the behaviour of harmine in water/AOT/cyclohexane and water/lecithin/cyclohexane microemulsions.http://www.sciencedirect.com/science/article/B6TFR-416K8BS-12/1/1e48ace7f73afe3996e2e8a782a190d

    Antimicrobial activity of the essential oils of Dittrichia viscosa subsp viscosa on Helicobacter pylori

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    Dittrichia viscosa subsp. viscosa (Compositae) is found on edges, wood clearings and in waste places of the Iberian Peninsula. Aerial parts of D. viscosa were collected at flowering phase in September-October 2001 around Lisbon, Portugal and the essential oils isolated by hydro-distillation for 4 h using a Clevenger-type apparatus. The oils were analyzed by gas chromatography and gas chromatography-mass spectrometry. Preliminary examination of the essential oils allowed the identification of 32 components. Only four components reached percentages over 5%: fokienol (11.8%), T-muurorol (7.9%), (E)-nerolidol (5.5%) and delta-cadinene (5.0%). The essential oils were tested against Helicobacterpylori and Listeria monocytogenes. Essential oils did not have antimicrobial activity against L. monocytogenes. The essential oil at 0.88 to 22.22 mu g.ml(-1) did not inhibit the growth of H. pylori, affected the growth slightly at 44.40 mu g.ml(-1), and completely inhibited the growth at 88.80 to 133.20 mu g.ml(-1) Results show that use of D. viscosa essential oil in the treatment of gastric disorders caused by H. pylori can be effective

    Anxiety, depression, traumatic stress and quality of life in colorectal cancer after different treatments: A study with Portuguese patients and their partners

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    Purpose: This study examines the impact of different modes of treatment on depression, anxiety, traumatic stress and quality of life in colorectal cancer patients and their partners. Methods: The sample was comprised of 114 oncology patients and 67 partners. All patients were diagnosed with colorectal cancer. Participants were recruited from an Oncology Hospital in the North of Portugal and had been submitted to three modes of treatment: surgery, surgery plus chemotherapy or surgery followed by radiotherapy. Results: The results showed that patients who received only surgery, as treatment, had lower levels of depression, anxiety and traumatic stress symptoms when compared with patients who received surgery and chemotherapy or surgery plus radiotherapy. Partners of surgical patients presented lower levels of state anxiety and traumatic stress symptoms when compared with the other two groups. Patients with more depression had partners also more depressed. No relationship was found between anxiety and traumatic stress symptoms in patients and partners. Patients who received a diagnosis longer than 12 months had more traumatic stress, intrusion and hypervigilance. Patients with illness recurrence showed more traumatic symptoms. Anxiety and depression were the main predictors of patient’s quality of life. Traumatic stress was a predictor of symptom distress - pain/bowel pattern. Conclusion: This study highlights the importance of providing psychological interventions for cancer patients and their partners. Chemotherapy patients and those diagnosed over a year, as well as their partners, are more at risk

    The general purpose analog computer and computable analysis are two equivalent paradigms of analog computation

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    In this paper we revisit one of the rst models of analog computation, Shannon's General Purpose Analog Computer (GPAC). The GPAC has often been argued to be weaker than computable analysis. As main contribution, we show that if we change the notion of GPACcomputability in a natural way, we compute exactly all real computable functions (in the sense of computable analysis). Moreover, since GPACs are equivalent to systems of polynomial di erential equations then we show that all real computable functions can be de ned by such models

    Generalized Totalizer Encoding for Pseudo-Boolean Constraints

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    Pseudo-Boolean constraints, also known as 0-1 Integer Linear Constraints, are used to model many real-world problems. A common approach to solve these constraints is to encode them into a SAT formula. The runtime of the SAT solver on such formula is sensitive to the manner in which the given pseudo-Boolean constraints are encoded. In this paper, we propose generalized Totalizer encoding (GTE), which is an arc-consistency preserving extension of the Totalizer encoding to pseudo-Boolean constraints. Unlike some other encodings, the number of auxiliary variables required for GTE does not depend on the magnitudes of the coefficients. Instead, it depends on the number of distinct combinations of these coefficients. We show the superiority of GTE with respect to other encodings when large pseudo-Boolean constraints have low number of distinct coefficients. Our experimental results also show that GTE remains competitive even when the pseudo-Boolean constraints do not have this characteristic.Comment: 10 pages, 2 figures, 2 tables. To be published in 21st International Conference on Principles and Practice of Constraint Programming 201

    Fluorescence and diffuse reflectance spectroscopy for early cancer detection using a new strategy towards the development of a miniaturized system

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    This paper describes the design of a miniature, cost-effective spectroscopy system for assessing tissue biochemical and morphological information using a few wavelengths. This instrument will integrate thin-film optical filters and silicon photodiodes, avoiding the use of a spectrograph and optical fibers. The components in the set-up design are described. The feasibility of using only 16 wavelengths to accurately extract tissue properties is confirmed on physical tissue models. Also, the suitable spectral performance of several optical filters for the selection of these wavelengths is demonstrated. The small size of this device will enable implementation in an endoscopic capsule.This research was supported by the Portuguese Foundation of Science and Technology and the MIT|Portugal Program (SFRH/BD/38978/2007

    Autofluorescence spectroscopy of a human gastrointestinal carcinoma cell line - design of optical sensors for the detection of early stage cancer

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    Human tissues show autofluorescence (AF) emission spectra when excited by ultraviolet or shortwavelength visible light. The intensity and shape of these spectra are dependent on the tissues pathological state and, therefore, its measurement gives information about the degree of malignant transformations that could lead to cancer. In this article, it is characterized the AF spectra of one human gastrointestinal carcinoma cell line (CACO-2). The obtained results showed significant AF signal for the presence of amino acids. The spectral information obtained can be used for the design of fluorescence optical sensors that will be incorporated on an endoscopic capsule, for measuring the AF emission spectra of normal and cancer cells. This integrated optical system will innovate on the diagnosis of early stage cancer
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