147 research outputs found

    Competition between spin density wave order and superconductivity in the underdoped cuprates

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    We describe the interplay between d-wave superconductivity and spin density wave (SDW) order in a theory of the hole-doped cuprates at hole densities below optimal doping. The theory assumes local SDW order, and associated electron and hole pocket Fermi surfaces of charge carriers in the normal state. We describe quantum and thermal fluctuations in the orientation of the local SDW order, which lead to d-wave superconductivity: we compute the superconducting critical temperature and magnetic field in a `minimal' universal theory. We also describe the back-action of the superconductivity on the SDW order, showing that SDW order is more stable in the metal. Our results capture key aspects of the phase diagram of Demler et al. (cond-mat/0103192) obtained in a phenomenological quantum theory of competing orders. Finally, we propose a finite temperature crossover phase diagram for the cuprates. In the metallic state, these are controlled by a `hidden' quantum critical point near optimal doping involving the onset of SDW order in a metal. However, the onset of superconductivity results in a decrease in stability of the SDW order, and consequently the actual SDW quantum critical point appears at a significantly lower doping. All our analysis is placed in the context of recent experimental results.Comment: 27 pages, 11 figures; (v2) added clarifications and refs, and corrected numerical errors (thanks to A. Chubukov

    Co-Clustering Network-Constrained Trajectory Data

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    Recently, clustering moving object trajectories kept gaining interest from both the data mining and machine learning communities. This problem, however, was studied mainly and extensively in the setting where moving objects can move freely on the euclidean space. In this paper, we study the problem of clustering trajectories of vehicles whose movement is restricted by the underlying road network. We model relations between these trajectories and road segments as a bipartite graph and we try to cluster its vertices. We demonstrate our approaches on synthetic data and show how it could be useful in inferring knowledge about the flow dynamics and the behavior of the drivers using the road network

    Radio frequency spectroscopy of a strongly imbalanced Feshbach-resonant Fermi gas

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    A sufficiently large species imbalance (polarization) in a two-component Feshbach resonant Fermi gas is known to drive the system into its normal state. We show that the resulting strongly-interacting state is a conventional Fermi liquid, that is, however, strongly renormalized by pairing fluctuations. Using a controlled 1/N expansion, we calculate the properties of this state with a particular emphasis on the atomic spectral function, the momentum distribution functions displaying the Migdal discontinuity, and the radio frequency (RF) spectrum. We discuss the latter in the light of the recent experiments of Schunck et al. (cond-mat/0702066) on such a resonant Fermi gas, and show that the observations are consistent with a conventional, but strongly renormalized Fermi-liquid picture.Comment: 10 pages, 5 figures; (v2) Numerous minor update

    A microfluidic approach to rapid sperm recovery from heterogeneous cell suspensions

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    The isolation of sperm cells from background cell populations and debris is an essential step in all assisted reproductive technologies. Conventional techniques for sperm recovery from testicular sperm extractions stagnate at the sample processing stage, where it can take several hours to identify viable sperm from a background of collateral cells such as white bloods cells (WBCs), red blood cells (RBCs), epithelial cells (ECs) and in some cases cancer cells. Manual identification of sperm from contaminating cells and debris is a tedious and time-consuming operation that can be suitably addressed through inertial microfluidics. Microfluidics has proven an effective technology for high-quality sperm selection based on motility. However, motility-based selection methods cannot cater for viable, non-motile sperm often present in testicular or epididymal sperm extractions and aspirations. This study demonstrates the use of a 3D printed inertial microfluidic device for the separation of sperm cells from a mixed suspension of WBCs, RBCs, ECs, and leukemic cancer cells. This technology presents a 36-fold time improvement for the recovery of sperm cells (> 96%) by separating sperm, RBCS, WBCs, ECs and cancer cells into tight bands in less than 5 min. Furthermore, microfluidic processing of sperm has no impact on sperm parameters; vitality, motility, morphology, or DNA fragmentation of sperm. Applying inertial microfluidics for non-motile sperm recovery can greatly improve the current processing procedure of testicular sperm extractions, simplifying the fertility outcomes for severe forms of male infertility that warrant the surgery

    Lack of evidence of disease contamination in ovarian tissue harvested for cryopreservation from patients with Hodgkin lymphoma and analysis of factors predictive of oocyte yield

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    Ovarian cryopreservation is a promising technique to preserve fertility in women with Hodgkin lymphoma (HL) treated with chemotherapy. Thus, the aim of this study was to examine harvested ovarian tissue for subclinical involvement by HL by morphology/immunohistochemistry, and to define patient and treatment factors predictive of oocyte yield. This was a retrospective analysis of 26 ovarian tissue samples harvested for cryopreservation from women with HL. Histology, immunohistochemistry and follicle density (number mm−3) was examined. Disease status and preharvest chemotherapy details were obtained on 24 patients. The median age was 22 years (range 13–29). Seven of 24 patients had infradiaphragmatic disease at time of harvest. Nine of 20 patients had received chemotherapy preharvest (ABVD (Adriamycin®, Bleomycin, Vinblastine and Dacarbazine)=7, other regimens=2). The seven receiving ABVD showed no difference in follicle density compared to patients not receiving treatment (n=14); (median=1555 vs 1620 mm3 P=0.97). Follicle density measurement showed no correlation with patient age (R2=0.0001, P=0.99). There was no evidence of HL involvement in the 26 samples examined (95% CI=0–11%). In conclusion, subclinical involvement of HL has not been identified in ovarian tissue, even when patients have infradiaphragmatic disease. Furthermore, the quality of tissue harvested does not appear to be adversely affected by patient's age or prior ABVD chemotherapy

    Omnidirectional wavelength selective emitters/absorbers based on dielectric-filled anti-reflection coated two-dimensional metallic photonic crystals

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    We demonstrate designs of dielectric-filled anti-reflection coated (ARC) two-dimensional (2D) metallic photonic crystals (MPhCs) capable of omnidirectional, polarization insensitive, wavelength selective emission/absorption. Up to 26% improvement in hemispherically averaged emittance/absorptance below the cutoff wavelength is observed for optimized hafnium oxide filled 2D tantalum (Ta) PhCs over the unfilled 2D Ta PhCs. The optimized designs possess high hemispherically averaged emittance/absorptance of 0.86 at wavelengths below the cutoff wavelength and low hemispherically averaged emittance/absorptance of 0.12 at wavelengths above the cutoff wavelength, which is extremely promising for applications such as thermophotovoltaic energy conversion, solar absorption, and infrared spectroscopy.Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies (Contract W911NF-13-D-0001)United States. Dept. of Energy. Office of Science (Solid-State Solar-Thermal Energy Conversion Center Grant DE-SC0001299

    Evaluation of zona pellucida birefringence intensity during in vitro maturation of oocytes from stimulated cycles

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    Background: This study evaluated whether there is a relationship between the zona pellucida birefringence (ZP-BF) intensity and the nuclear (NM) and cytoplasmic (CM) in vitro maturation of human oocytes from stimulated cycles.Results: The ZP-BF was evaluated under an inverted microscope with a polarizing optical system and was scored as high/positive (when the ZP image presented a uniform and intense birefringence) or low/negative (when the image presented moderate and heterogeneous birefringence). CM was analyzed by evaluating the distribution of cortical granules (CGs) throughout the ooplasm by immunofluorescence staining. CM was classified as: complete, when CG was localized in the periphery; incomplete, when oocytes presented a cluster of CGs in the center; or in transition, when oocytes had both in clusters throughout cytoplasm and distributed in a layer in the cytoplasm periphery Nuclear maturation: From a total of 83 germinal vesicle (GV) stage oocytes, 58 of oocytes (69.9%) reached NM at the metaphase II stage. From these 58 oocytes matured in vitro, the high/positively scoring ZP-BF was presented in 82.7% of oocytes at the GV stage, in 75.8% of oocytes when at the metaphase I, and in 82.7% when oocytes reached MII. No relationship was observed between NM and ZP-BF positive/negative scores (P = 0.55). These variables had a low Pearson's correlation coefficient (r = 0.081). Cytoplasmic maturation: A total of 85 in vitro-matured MII oocytes were fixed for CM evaluation. Forty-nine oocytes of them (57.6%) showed the complete CM, 30 (61.2%) presented a high/positively scoring ZP-BF and 19 (38.8%) had a low/negatively scoring ZP-BF. From 36 oocytes (42.3%) with incomplete CM, 18 (50%) presented a high/positively scoring ZPBF and 18 (50%) had a low/negatively scoring ZP-BF. No relationship was observed between CM and ZP-BF positive/negative scores (P = 0.42). These variables had a low Pearson's correlation coefficient (r = 0.11).Conclusions: The current study demonstrated an absence of relationship between ZP-BF high/positive or low/negative score and nuclear and cytoplasmic in vitro maturation of oocytes from stimulation cycles

    Quantum-critical pairing with varying exponents

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    We analyse the onset temperature T_p for the pairing in cuprate superconductors at small doping, when tendency towards antiferromagnetism is strong. We consider the model of Moon and Sachdev (MS), which assumes that electron and hole pockets survive in a paramagnetic phase. Within this model, the pairing between fermions is mediated by a gauge boson, whose propagator remains massless in a paramagnet. We relate the MS model to a generic \gamma-model of quantum-critical pairing with the pairing kernel \lambda (\Omega) \propto 1/\Omega^{\gamma}. We show that, over some range of parameters, the MS model is equivalent to the \gamma-model with \gamma =1/3 (\lambda (\Omega) \propto \Omega^{-1/3}). We find, however, that the parameter range where this analogy works is bounded on both ends. At larger deviations from a magnetic phase, the MS model becomes equivalent to the \gamma-model with varying \gamma >1/3, whose value depends on the distance to a magnetic transition and approaches \gamma =1 deep in a paramagnetic phase. Very near the transition, the MS model becomes equivalent to the \gamma-model with varying \gamma <1/3. Right at the magnetic QCP, the MS model is equivalent to the \gamma-model with \gamma =0+ (\lambda (\Omega) \propto \log \Omega), which is the model for color superconductivity. Using this analogy, we verified the formula for T_c derived for color superconductivity.Comment: 10 pages, 8 figures, submitted to JLTP for a focused issue on Quantum Phase Transition

    Managing deliberate self-harm in young people: An evaluation of a training program developed for school welfare staff using a longitudinal research design

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    BACKGROUND: Although deliberate self-harm is prevalent among young people, many who engage in deliberate self-harm receive sub-optimal care. Although schools are a well placed setting to support young people who engage in self-harm there are no specific training packages designed to assist school welfare staff to support these young people.The current study aimed to design, deliver and evaluate a training course specifically for school staff. METHODS: The study employed a longitudinal design. Two hundred and thirteen people participated in the training and evaluation. A questionnaire was administered at baseline, immediately after the training and at 6-month follow-up in order to determine if the training led to improvements in confidence when working with young people who self-harm, perceived skill, knowledge of, and attitudes towards people who self harm. RESULTS: Prior to the course, the majority of participants demonstrated relatively high levels of confidence, perceived skill and knowledge of self-harm and endorsed relatively positive attitudes towards people who engage in self-harm. Despite this, significant improvements were observed in terms of increased confidence, increased perceptions of skill along with increased knowledge of deliberate self-harm. These improvements were sustained over the follow-up period. CONCLUSION: The results demonstrated that the provision of specifically designed training can help school welfare staff to feel better equipped to support young people who are engaging in deliberate self-harm
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