912 research outputs found
Kontribusi Pasar Tradisional Dan Pasar Modern Terhadap Pendapatan Asli Daerah Kota Semarang Tahun 2011 (Studi Kasus Di Wilayah Kecamatan Banyumanik)
Perkembangan pasar modern yang semakin tak terkendali di Kota Semarangditandai dengan banyaknya jumlah pasar modern melebihi jumlah pasar tradisionalnya.Hal ini berdampak negatif terhadap pertumbuhan pasar tradisional yakni dapatmenggeser peran pasar tradisional sebagai tempat masyarakat berbelanja. Denganadanya pasar modern yang menyediakan fasilitas yang bagus, maka masyarakat akancenderung berbelanja di pasar modern dari pada di pasar tradisional.Penelitian ini dilakukan untuk mengetahui dan membandingkan seberapa besarkontribusi pasar tradisional dan pasar modern bagi Pendapatan Asli Daerah (PAD) KotaSemarang tahun 2011, bagaimana mekanisme kontribusi dilakukan dan apa saja regulasiyang digunakan oleh Pemerintah Kota Semarang dalam mengatur kedua pasar tersebut.Penulis mengambil objek penelitian di Wilayah Kecamatan Banyumanik untukkemudahan dan kapabilitas data yang diperoleh. Metode yang digunakan dalampenelitian ini menggunakan metode kualitatif yaitu dengan menggambarkan keadaansubjek dan objek penelitian pada saat sekarang berdasarkan fakta-fakta yang tampak.Dalam pengumpulan data, menggunakan teknik wawancara sebagai data primer,sedangkan data sekunder berasal dari buku literatur dan peraturan-peraturan pemerintah.Hasil penelitian menunjukan bahwa pasar tradisional di Wilayah KecamatanBanyumanik berkontribusi terhadap Pendapatan Asli Daerah Kota Semarang sebesarRp. 364.128.420,- pada tahun 2011 sedangkan pasar modern tidak diketahui. Pasartradisional berkontribusi melalui retribusi pasar yang dipungut setiap hari dan setiapbulan, sedangkan pasar modern berkontribusi melalui retribusi perijinan sebelummendirikan pasar modern, yakni melalui Ijin Mendirikan Bangunan (IMB) dan IjinGangguan (HO). Namun karena dalam perijinannya pengusaha pasar modernmenggunakan nama pribadi dan tidak menggunakan nama USAhanya, sehingga tidakdiketahui besarnya kontribusi yang berasal dari pasar modern. Hal ini belum bisa diatasioleh Pemerintah Kota Semarang karena tidak ada Perda yang mengatur pasar modern.Pemerintah Kota Semarang sebagai instansi resmi yang berwenang mengaturpasar di Wilayahnya harus segera mengesahkan peraturan daerah tentang pengelolaanpasar modern agar keberadaannya tidak mengganggu pertumbuhan pasar tradisionalsehingga kedua pasar ini dapat berkembang tanpa ada salah satu yang merasa dirugikan
Construction and measurements of a vacuum-swing-adsorption radon-mitigation system
Long-lived alpha and beta emitters in the Rn decay chain on (and
near) detector surfaces may be the limiting background in many experiments
attempting to detect dark matter or neutrinoless double-beta decay, and in
screening detectors. In order to reduce backgrounds from radon-daughter
plate-out onto the wires of the BetaCage during its assembly, an
ultra-low-radon cleanroom is being commissioned at Syracuse University using a
vacuum-swing-adsorption radon-mitigation system. The radon filter shows
~20 reduction at its output, from 7.470.56 to 0.370.12
Bq/m, and the cleanroom radon activity meets project requirements, with a
lowest achieved value consistent with that of the filter, and levels
consistently < 2 Bq/m.Comment: 5 pages, 3 figures, Proceedings of Low Radioactivity Techniques (LRT)
2013, Gran Sasso, Italy, April 10-12, 201
Urinary diversion and bladder reconstruction/replacement using intestinal segments for intractable incontinence or following cystectomy
Background Surgery performed to improve or replace the function of the diseased urinary bladder has been carried out for over a century. Main reasons for improving or replacing the function of the urinary bladder are bladder cancer, neurogenic bladder dysfunction, detrusor overactivity and chronic inflammatory diseases of the bladder (such as interstitial cystitis, tuberculosis and schistosomiasis). There is still much uncertainty about the best surgical approach. Options available at the present time include: (1) conduit diversion (the creation of various intestinal conduits to the skin) or continent diversion (which includes either a rectal reservoir or continent cutaneous diversion), (2) bladder reconstruction and (3) replacement of the bladder with various intestinal segments. Objectives To determine the best way of improving or replacing the function of the lower urinary tract using intestinal segments when the bladder has to be removed or when it has been rendered useless or dangerous by disease. Search methods We searched the Cochrane Incontinence Group Specialised Trials Register (searched 28 October 2011), which contains trials identified from the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and CINAHL, and handsearching of journals and conference proceedings, and the reference lists of relevant articles. Selection criteria All randomised or quasi-randomised controlled trials of surgery involving transposition of an intestinal segment into the urinary tract. Data collection and analysis Trials were evaluated for appropriateness for inclusion and for risk of bias by the review authors. Three review authors were involved in the data extraction. Data were combined in a meta-analysis when appropriate. Main results Five trials met the inclusion criteria with a total of 355 participants. These trials addressed only five of the 14 comparisons pre-specified in the protocol. One trial reported no statistically significant differences in the incidence of upper urinary tract infection, uretero-intestinal stenosis and renal deterioration in the comparison of continent diversion with conduit diversion. The confidence intervals were all wide, however, and did not rule out important clinical differences. In a second trial, there was no reported difference in the incidence of upper urinary tract infection and uretero-intestinal stenosis when conduit diversions were fashioned from either ileum or colon. A meta-analysis of two trials showed no statistically significant difference in daytime or nocturnal incontinence amongst participants who were randomised to ileocolonic/ileocaecal segment bladder replacement compared to an ileal bladder replacement. However, one small trial suggested that bladder replacement using an ileal segment compared to using an ileocolonic segment may be better in terms of lower rates of nocturnal incontinence. There were no differences in the incidence of dilatation of upper tract, daytime urinary incontinence or wound infection using different intestinal segments for bladder replacement. However the data were reported for 'renal units', but not in a form that allowed appropriate patient-based paired analyses. No statistically significant difference was found in the incidence of renal scarring between anti-refluxing versus freely refluxing uretero-intestinal anastomotic techniques in conduit diversions and bladder replacement groups. Again, the outcome data were not reported as paired analysis or in form to carry out paired analysis. Authors' conclusions The evidence from the included trials was very limited. Only five studies met the inclusion criteria; these were small, of moderate or poor methodological quality, and reported few of the pre-selected outcome measures. This review did not find any evidence that bladder replacement (orthotopic or continent diversion) was better than conduit diversion following cystectomy for cancer. There was no evidence to suggest that bladder reconstruction was better than conduit diversion for benign disease. The clinical significance of data from one small trial suggesting that bladder replacement using an ileal segment compared to using an ileocolonic segment is better in terms of lower rates of nocturnal incontinence is uncertain. The small amount of usable evidence for this review suggests that collaborative multi centre studies should be organised, using random allocation where possible. This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2012, Issue 2. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.</p
Trends in the availability and usage of electrophysical agents in physiotherapy practices from 1990 to 2010: A review
This is the Pre-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Maney PublishingBackground: The use of electrophysical agents has a historically important role in physiotherapy practice. There are anecdotal reports that the availability and usage of electrotherapy modalities are declining, which may have implications for physiotherapy practice. The aim of this literature review was to provide scientific evidence on electrotherapy usage in the last 20 years by identifying trends in availability, use, and non-use of nine electrotherapeutic modalities in physiotherapy practices during 1990s and 2000s. Methods: Review of empirical studies published in the English language from 1990 to 2010 and identified through searching online bibliographic databases, which included: Medline/OvidSP, PubMed Central, CINAHL/EBSCOhost, ScienceDirect, Scopus, ISI Web of Science, and Google Scholar. Findings: In the last 20 years, ultrasound availability and usage show increasing trends in several countries. The availability and use of pulsed shortwave diathermy and laser have shown steady trends. Transcutaneous electrical nerve stimulation, interferential, and biofeedback availability and usage have shown increasing trends in the UK and decreasing trends in Australia and the Republic of Ireland. Trends of continuous shortwave diathermy availability and use are declining irrespective of the country of the study. The availability and usage of microwave diathermy and H-wave show steeply declining trends, while there is a sharp rise in their non-availability over the last several years. Conclusions: The availability and use of electrophysical agents have greatly changed in the last 20 years. Declining trends in the availability and usage along with increasing trend of non-availability of electrotherapy modalities may have implications for electrotherapy education, training, and practice in the coming years.This study was funded by Health & Safety Executive, UK (grant no. 4371/R47.022)
Divisions of labor in the thiamin biosynthetic pathway among organs of maize
The B vitamin thiamin is essential for central metabolism in all cellular organisms including plants. While plants synthesize thiamin de novo, organs vary widely in their capacities for thiamin synthesis. We use a transcriptomics approach to appraise the distribution of de novo synthesis and thiamin salvage pathways among organs of maize. We identify at least six developmental contexts in which metabolically active, non-photosynthetic organs exhibit low expression of one or both branches of the de novo thiamin biosynthetic pathway indicating a dependence on inter-cellular transport of thiamin and/or thiamin precursors. Neither the thiazole (THI4) nor pyrimidine (THIC) branches of the pathway are expressed in developing pollen implying a dependence on import of thiamin from surrounding floral and inflorescence organs. Consistent with that hypothesis, organs of the male inflorescence and flowers are shown to have high relative expression of the thiamin biosynthetic pathway and comparatively high thiamin contents. By contrast, divergent patterns of THIC and THI4 expression occur in the shoot apical meristem, embyro sac, embryo, endosperm, and root-tips suggesting that these sink organs acquire significant amounts of thiamin via salvage pathways. In the root and shoot meristems, expression of THIC in the absence of THI4 indicates a capacity for thiamin synthesis via salvage of thiazole, whereas the opposite pattern obtains in embryo and endosperm implying that seed storage organs are poised for pyrimidine salvage. Finally, stable isotope labeling experiments set an upper limit on the rate of de novo thiamin biosynthesis in maize leaf explants. Overall, the observed patterns of thiamin biosynthetic gene expression mirror the strategies for thiamin acquisition that have evolved in bacteria
A Novel, non-invasive Test Enabling Bladder Cancer Detection in Urine Sediment of Patients Presenting with Haematuria:A Prospective Multicentre Performance Evaluation of ADXBLADDER
Bladder cancer is the sixth most commonly diagnosed cancer in the European Union. Here, we evaluate the performance of a novel, commercially available enzyme-linked immunosorbent assay utilising MCM5 antibodies (ADXBLADDER; Arquer Diagnostics Ltd, Sunderland, UK) for the detection of bladder cancer, in a blinded, prospective study of 856 patients, across seven centres, presenting with haematuria. The results were compared with the patients’ clinical data and final diagnosis as defined by the results of the imaging and cystoscopy, with a prevalence of bladder cancer of 8.6%. ADXBLADDER detected bladder tumours in 54/74 cancers, giving overall sensitivity of 73.0% and an overall negative predictive value (NPV) of 96.4%. Sensitivity and NPV of ADXBLADDER were highest in muscle-invasive bladder cancer, both at 100%, and on analysis of non-pTa (pT1 and above) tumours, the sensitivity for detection was 97% with an NPV of 99.8%. A subset of 173 patients had matching cytology data; of these patients, 18 were positive for bladder cancer. ADXBLADDER detected 16/18 of these cancers, whilst cytology was positive in only four of 18, providing evidence that ADXBLADDER may be a more sensitive test for bladder cancer than standard urine cytology. Patient summary: We conducted a large clinical study of a novel, simple urine test (ADXBLADDER), which measures a protein (MCM5) in urine and can be used to detect bladder cancer in patients. We recruited 856 patients and demonstrated that the new urine test can detect bladder cancer with a high degree of accuracy, performing better than the most commonly used urine test—urine cytology. In conclusion, this novel ADXBLADDER urine test can be used to help detect bladder cancers and it can replace the current, standard urine test. The ADXBLADDER test measures the novel biomarker MCM5. Outperforming cytology, and achieving one of the highest sensitivities and negative predictive values of any urine test for bladder cancer diagnosis, it has the potential to improve the bladder cancer diagnostic pathway.</p
INDIGO : better geomagnetic observatories where we need them
The INDIGO project aims to improve the global coverage of digital observatories by deploying digital magnetometer systems in:
i) Observatories where existing analog recording equipment is in need of upgrading.
ii) Newly established digital observatories.
iii) Existing digital observatories for the purpose of quality control and redundancy.
In implementing the project and selecting suitable sites, special attention is paid to parts of the Earth devoid of magnetic observatories, increasing the reliability and long-term operation of existing observatories and cost-effective use of local resources.
The Poster reviews the current status of the project. We examine the different steps and initiatives taken since the initiation of INDIGO in 2004 and assess their effectiveness in achieving progress towards our aims of improving global coverage and enhanced data quality
Effectiveness of an antimicrobial treatment scheme in a confined glanders outbreak
BACKGROUND: Glanders is a contagious and fatal zoonotic disease of solipeds caused by the Gram-negative bacterium Burkholderia (B.) mallei. Although regulations call for culling of diseased animals, certain situations e.g. wild life conservation, highly valuable breeding stock, could benefit from effective treatment schemes and post-exposure prophylaxis. RESULTS: Twenty three culture positive glanderous horses were successfully treated during a confined outbreak by applying a treatment protocol of 12 weeks duration based on the parenteral administration of enrofloxacin and trimethoprim plus sulfadiazine, followed by the oral administration of doxycycline. Induction of immunosupression in six randomly chosen horses after completion of treatment did not lead to recrudescence of disease. CONCLUSION: This study demonstrates that long term treatment of glanderous horses with a combination of various antibiotics seems to eliminate the agent from the organism. However, more studies are needed to test the effectiveness of this treatment regime on B. mallei strains from different endemic regions. Due to its cost and duration, this treatment can only be an option in certain situations and should not replace the current “testing and culling” policy, in conjunction with adequate compensation to prevent spreading of disease
Nanoparticle-Assisted Water-Flooding in Berea Sandstones
The use of nanoparticles to improve reservoir characterization or to enhance oil recovery (EOR) has recently received intensive interest; however, there are still many unresolved questions. This work reports a systematic study of the effect of rutile TiO2 nanoparticle-assisted brine flooding. Rutile ellipsoid TiO2 nanoparticles were synthesized and stabilized by trisodium citrate dihydrate for brine flooding of water-wet Berea sandstone cores. Careful characterization of the rock samples and nanomaterials before and after the flooding was conducted, and the relative contributions to the modified flooding results from the stabilizer and the nanoparticles of different concentrations were examined. The oil recovery performance was evaluated both at the breakthrough (BT) point and at the end of flooding (∼3.2 pore volumes). Nanoparticle migration behavior was also investigated in order to understand the potential mechanisms for oil recovery. The results showed that both nanoparticle transport rate and EOR effect were strongly dependent on the particle concentration. The oil recovery efficiency at the BT point was found to increase at low nanoparticle concentrations but decrease at higher values. A maximum 33% increase of the recovery factor was observed at the BT point for a TiO2 concentration of 20 ppm, but higher nanoparticle concentrations usually had higher ultimate recovery factors. The presence of an oil phase was found to accelerate the particle migration though the core. The discussion of various mechanisms suggested that the improvement in the mobility ratio, possible wettability change, and log-jamming effect were responsible for the observed phenomena
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