6,543 research outputs found

    System and Method for Air Launch from a Towed Aircraft

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    The invention is a system and method of air launching a powered launch vehicle into space or high altitude. More specifically, the invention is a tow aircraft which tows an unpowered glider, with the powered launch vehicle attached thereto, to launch altitude. The powered launch vehicle is released from the unpowered glider and powered on for launch

    Fiber R and D for the CMS HCAL

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    This paper documents the fiber R and D for the CMS hadron barrel calorimeter (HCAL). The R and D includes measurements of fiber flexibility, splicing, mirror reflectivity, relative light yield, attenuation length, radiation effects, absolute light yield, and transverse tile uniformity. Schematics of the hardware for each measurement are shown. These studies are done for different diameters and kinds of multiclad fiber.Comment: 23 pages, 30 Figures 89 pages, 41 figures, corresponding author: H. Budd, [email protected]

    Interplay of Mre11 Nuclease with Dna2 plus Sgs1 in Rad51-Dependent Recombinational Repair

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    The Mre11/Rad50/Xrs2 complex initiates IR repair by binding to the end of a double-strand break, resulting in 5′ to 3′ exonuclease degradation creating a single-stranded 3′ overhang competent for strand invasion into the unbroken chromosome. The nuclease(s) involved are not well understood. Mre11 encodes a nuclease, but it has 3′ to 5′, rather than 5′ to 3′ activity. Furthermore, mutations that inactivate only the nuclease activity of Mre11 but not its other repair functions, mre11-D56N and mre11-H125N, are resistant to IR. This suggests that another nuclease can catalyze 5′ to 3′ degradation. One candidate nuclease that has not been tested to date because it is encoded by an essential gene is the Dna2 helicase/nuclease. We recently reported the ability to suppress the lethality of a dna2Δ with a pif1Δ. The dna2Δ pif1Δ mutant is IR-resistant. We have determined that dna2Δ pif1Δ mre11-D56N and dna2Δ pif1Δ mre11-H125N strains are equally as sensitive to IR as mre11Δ strains, suggesting that in the absence of Dna2, Mre11 nuclease carries out repair. The dna2Δ pif1Δ mre11-D56N triple mutant is complemented by plasmids expressing Mre11, Dna2 or dna2K1080E, a mutant with defective helicase and functional nuclease, demonstrating that the nuclease of Dna2 compensates for the absence of Mre11 nuclease in IR repair, presumably in 5′ to 3′ degradation at DSB ends. We further show that sgs1Δ mre11-H125N, but not sgs1Δ, is very sensitive to IR, implicating the Sgs1 helicase in the Dna2-mediated pathway

    Operational and research aspects of a radio-controlled model flight test program

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    The operational and research aspects of a subscale, radio-controlled model flight test program are presented. By using low-cost free-flying models, an approach was developed for obtaining research-quality vehicle performance and aerodynamic information. The advantages and limitations learned by applying this approach to a specific flight test program are described. The research quality of the data acquired shows that model flight testing is practical for obtaining consistent and repeatable flight data

    User's manual for EZPLOT version 5.5: A FORTRAN program for 2-dimensional graphic display of data

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    EZPLOT is a computer applications program that converts data resident on a file into a plot displayed on the screen of a graphics terminal. This program generates either time history or x-y plots in response to commands entered interactively from a terminal keyboard. Plot parameters consist of a single independent parameter and from one to eight dependent parameters. Various line patterns, symbol shapes, axis scales, text labels, and data modification techniques are available. This user's manual describes EZPLOT as it is implemented on the Ames Research Center, Dryden Research Facility ELXSI computer using DI-3000 graphics software tools

    Towed Glider Air Launch System

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    Evaluating the Evolutionary Origins of Unexpected Character Distributions within the Bacterial Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum

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    Recently, several characters that are absent from most bacteria, but which are found in many eukaryotes or archaea, have been identified within the bacterial Planctomycetes-Verrucomicrobia-Chlamydiae (PVC) superphylum. Hypotheses of the evolutionary history of such characters are commonly based on the inference of phylogenies of gene or protein families associated with the traits, estimated from multiple sequence alignments (MSAs). So far, studies of this kind have focused on the distribution of (i) two genes involved in the synthesis of sterol, (ii) tubulin genes, and (iii) c1 transfer genes. In many cases, these analyses have concluded that horizontal gene transfer (HGT) is likely to have played a role in shaping the taxonomic distribution of these gene families. In this article, we describe several issues with the inference of HGT from such analyses, in particular concerning the considerable uncertainty associated with our estimation of both gene family phylogenies (especially those containing ancient lineage divergences) and the Tree of Life (ToL), and the need for wider use and further development of explicit probabilistic models to compare hypotheses of vertical and horizontal genetic transmission. We suggest that data which is often taken as evidence for the occurrence of ancient HGT events may not be as convincing as is commonly described, and consideration of alternative theories is recommended. While focusing on analyses including PVCs, this discussion is also relevant for inferences of HGT involving other groups of organisms

    Difference schemes with point symmetries and their numerical tests

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    Symmetry preserving difference schemes approximating second and third order ordinary differential equations are presented. They have the same three or four-dimensional symmetry groups as the original differential equations. The new difference schemes are tested as numerical methods. The obtained numerical solutions are shown to be much more accurate than those obtained by standard methods without an increase in cost. For an example involving a solution with a singularity in the integration region the symmetry preserving scheme, contrary to standard ones, provides solutions valid beyond the singular point.Comment: 26 pages 7 figure

    A heat transfer with a source: the complete set of invariant difference schemes

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    In this letter we present the set of invariant difference equations and meshes which preserve the Lie group symmetries of the equation u_{t}=(K(u)u_{x})_{x}+Q(u). All special cases of K(u) and Q(u) that extend the symmetry group admitted by the differential equation are considered. This paper completes the paper [J. Phys. A: Math. Gen. 30, no. 23 (1997) 8139-8155], where a few invariant models for heat transfer equations were presented.Comment: arxiv version is already officia
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