Located horizon variation study Final report, 20 May 1968 - 13 Jan. 1969

Meteorological data interpolation techniques for computing horizon radiance profiles evaluated for possible error introduction

A methodology to facilitate knowledge sharing in the new product development process

This paper describes the findings of an exploratory case study to investigate knowledge sharing problems in the new product development (NPD) process of a multi-national manufacturing company, and classifies the problems into three categories, i.e. (a) the lack of an explicit definition and prioritization of information about the knowledge used in the NPD process, (b) the challenges raised by, and lack of tools to support, knowledge sharing in a multilingual, multidisciplinary environment, and (c) the dissemination of information about the task and process knowledge to process users. An ontology-based methodology has been proposed, and a pilot study has been carried out to solve these problems. The pilot study includes the selection of suitable candidate tasks (or sub-processes) for the study, the elicitation of information about the selected task knowledge, the development of task knowledge ontology, and a mechanism to visualize and disseminate the ontology to process users. Early implementation and tests have shown that the proposed methodology may be used to facilitate knowledge sharing in the new product development process. The project was sponsored by a leading heating system manufacturer and further tests will be carried out with real industrial problems

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

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A Prototype Method and Tool to Facilitate Knowledge Sharing in the New Product Development Process

New Product Development (NPD) plays a critical role in the success of manufacturing firms. Activities in the product development process are dependent on the exchange of knowledge among NPD project team members. Increasingly, many organisations consider effective knowledge sharing to be a source of competitive advantage. However, the sharing of knowledge is often inhibited in various ways. This doctoral research presents an exploratory case study conducted at a multinational physical goods manufacturer. This investigation uncovered three, empirically derived and theoretically informed, barriers to knowledge sharing. They have been articulated as the lack of an explicit definition of information about the knowledge used and generated in the product development process, and the absence of mechanisms to make this information accessible in a multilingual environment and to disseminate it to NPD project team members. Collectively, these barriers inhibit a shared understanding of product development process knowledge. Existing knowledge management methodologies have focused on the capture of knowledge, rather than providing information about the knowledge and have not explicitly addressed issues regarding knowledge sharing in a multilingual environment. This thesis reports a prototype method and tool to facilitate knowledge sharing that addresses all three knowledge sharing barriers. Initially the research set out to identify and classify new product development process knowledge and then sought to determine what information about specific knowledge items is required by project teams. Based on the exploratory case findings, an ontology has been developed that formally defines information about this knowledge and allows it to be captured in a knowledge acquisition tool, thereby creating a knowledge base. A mechanism is provided to permit language labels to be attached to concepts and relations in the ontology, making it accessible to speakers of different languages. A dissemination tool allows the ontology and knowledge base to be viewed via a Web browser client. Essentially, the ontology and mechanisms facilitate a knowledge sharing capability. Some initial validation was conducted to better understand implementation issues and future deployment of the prototype method and tool in practice

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats

Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in behaviours related to salient, reward-paired cues. Objectives Here, we used designer receptors exclusively activated by designer drugs (DREADDs) to investigate the role of parafascicular (Pf) thalamic inputs to the dorsomedial striatum (DMS) using the five-choice serial reaction time task (5CSRTT) in rats. Methods The 5CSRTT requires sustained attention in order to detect spatially and temporally distributed visual cues and provides measures of inhibitory control related to impulsivity (premature responses) and compulsivity (perseverative responses). Rats underwent bilateral Pf injections of the DREADD vector, AAV2-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine. The DREADD agonist, clozapine N-oxide (CNO; 1 μl bilateral; 3 μM) or vehicle, was injected into DMS 1 h before behavioural testing. Task parameters were manipulated to increase attention load or reduce stimulus predictability respectively. Results We found that inhibition of the Pf-DMS projection significantly increased perseverative responses when stimulus predictability was reduced but had no effect on premature responses or response accuracy, even under increased attentional load. Control experiments showed no effects on locomotor activity in an open field. Conclusions These results complement previous lesion work in which the DMS and orbitofrontal cortex were similarly implicated in perseverative responses and suggest a specific role for thalamostriatal inputs in inhibitory control

Implementing QVT-R bidirectional model transformations using alloy

QVT Relations (QVT-R) is the standard language proposed by the OMG to specify bidirectional model transformations. Unfortunately, in part due to ambiguities and omissions in the original semantics, acceptance and development of effective tool support has been slow. Recently, the checking semantics of QVT-R has been clarified and formalized. In this paper we propose a QVT-R tool that complies to such semantics. Unlike any other existing tool, it also supports meta-models enriched with OCL constraints (thus avoiding returning ill-formed models), and proposes an alternative enforcement semantics that works according to the simple and predictable “principle of least change”. The implementation is based on an embedding of both QVT-R transformations and UML class diagrams (annotated with OCL) in Alloy, a lightweight formal specification language with support for automatic model finding via SAT solving.Fundação para a Ciência e a Tecnologi

MA.KETODAY COUNT: A MUTUAL SUPPORT GROUP FOR THE DYING

The purpose of· this paper is to discuss the aspects of a local chapter of 1Vlake Today Count. MTCis a mutual support group for persons with terminal illnesses. Organized in 1974, it is part afwhat tome have' called the tlhappy death movement." This movement seeks to make death more humane and less techtlOlogical. The paper addresses such'iuues:;;as reasons of joiningJ the nature of membership, and the gains for persons who join

Researching Student Community Service: An Opportunity to Promote Reflection?

In recent years there has been a growing interest in student community service. It is suggested that the students of the 1980\u27s and 90\u27s are returning to an ethic of community service. Organizations have developed to promote service from both the student and the academic perspectives. The Campus Outreach Opportunity League (COOL) is a student movement promoting community service. Campus Compact represents the academic administration interest in promoting student community service with presidents of institutions forming the membership in the organization. A third organization, the National Society of Internships and Experiential Education (NSIEE), includes student community service as a form of the more traditional field based learning/teaching strategies. Service-learning provides a mechanism for integrating community service within the overall mission of the academy. How do these trends developments manifest themselves on the local level? What interests do students bring and gain from community service? Is there a good fit between the structuring of student community service by academic planners and the interests that students bring to the service setting? This research will explore three motivational contexts in which students actively engage in community service. The three contexts are identified as altruistic, academic credit and tuition benefits

AN UNEASY ALLIANCE: DOCTORS OF GRIEF AND DOCTORS OF DIVINITY

This article explores the role relationship of olergy and funeral directors from the perspective of the funeral director. Much of the conflict can be explained from a socio-historical perspective as the status of the funeral director has been enhanced and that of the clergy has become more tenuous. Funeral directors are moving boldly into the area of itgrief counseling" which previously was the almost exclusive domain of the clergy. For their part, funeral directors see clergy involvement in funeral purchases as a particularly irritating role infringement. In a more positive vein, many funeral directors and clergy are engaging in open communication in a way that promotes "good grief" for the bereaved