126 research outputs found

    Ethanolic extract of polish propolis (EEP) in reaction with free radicals

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    Floods of June 2012 in Northeastern Minnesota

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    U.S. Geological Survey Scientific Investigations Report 2012–5283. Reston, VA: U.S. Geological Survey.This report is a summary description of the 2012 flooding in the Fond du Lac region of Lake Superior from a meteorological and hydrologic perspective. The report notes that the extent and depth of flooding in communities can be used for flood recovery efforts. Key points are reproduced below. Abstract: “During June 19–20, 2012, heavy rainfall, as much as 10 inches locally reported, caused severe flooding across northeastern Minnesota. The floods were exacerbated by wet antecedent conditions from a relatively rainy spring, with May 2012 as one of the wettest Mays on record in Duluth. The June 19–20, 2012, rainfall event set new records in Duluth, including greatest 2-day precipitation with 7.25 inches of rain. The heavy rains fell on three major watersheds: the Mississippi Headwaters; the St. Croix, which drains to the Mississippi River; and Western Lake Superior, which includes the St. Louis River and other tributaries to Lake Superior. Widespread flash and river flooding that resulted from the heavy rainfall caused evacuations of residents, and damages to residences, businesses, and infrastructure. In all, nine counties in northeastern Minnesota were declared Federal disaster areas as a result of the flooding. Peak-of-record streamflows were recorded at 13 U.S. Geological Survey stream gages as a result of the heavy rainfall. Flood-peak gage heights, peak streamflows, and annual exceedance probabilities were tabulated for 35 U.S. Geological Survey stream gages. Flood-peak streamflows in June 2012 had annual exceedance probabilities estimated to be less than 0.002 (0.2 percent; recurrence interval greater than 500 years) for five stream gages, and between 0.002 and 0.01 (1 percent; recurrence interval greater than 100 years) for four stream gages. High-water marks were identified and tabulated for the most severely affected communities of Barnum (Moose Horn River), Carlton (Otter Creek), Duluth Heights neighborhood of Duluth (Miller Creek), Fond du Lac neighborhood of Duluth (St. Louis River), Moose Lake (Moose Horn River and Moosehead Lake), and Thomson (Thomson Reservoir outflow near the St. Louis River). Flood-peak inundation maps and water-surface profiles were produced for these six severely affected communities. The inundation maps were constructed in a geographic information system by combining high-water-mark data with high-resolution digital elevation model data. The flood maps and profiles show the extent and depth of flooding through the communities and can be used for flood response and recovery efforts by local, county, State, and Federal agencies.

    Reaction of choosen compounds founded in EEP with free radicals

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    Сейсмічний експеримент TTZ-South

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    The wide-angle reflection and refraction (WARR) TTZ-South transect carried out in 2018 crosses the SW region of Ukraine and the SE region of Poland. The TTZ-South profile targeted the structure of the Earth’s crust and upper mantle of the Trans-European Suture Zone, as well as the southwestern segment of the East European Craton (slope of the Ukrainian Shield). The ~550 km long profile (~230 km in Poland and ~320 km in western Ukraine) is an extension of previously realized projects in Poland, TTZ (1993) and CEL03 (2000). The deep seismic sounding study along the TTZ-South profile using TEXAN and DATA-CUBE seismic stations (320 units) made it possible to obtain high-quality seismic records from eleven shot points (six in Ukraine and five in Poland). This paper presents a smooth P-wave velocity model based on first-arrival travel-time inversion using the FAST (First Arrival Seismic Tomography) code.The obtained image represents a preliminary velocity model which, according to the P-wave velocities, consists of a sedimentary layer and the crystalline crust that could comprise  upper, middle and lower crustal layers. The Moho interface, approximated by the 7.5 km/s isoline, is located at 45—47 km depth in the central part of the profile, shallowing to 40 and 37 km depth in the northern (Radom-Łysogóry Unit, Poland) and southern (Volyno-Podolian Monocline, Ukraine) segments of the profile, respectively. A peculiar feature of the velocity cross-section is a number of high-velocity bodies distinguished in the depth range of 10—35 km. Such high-velocity bodies were detected previously in the crust of the Radom-Łysogóry Unit. These bodies, inferred at depths of 10—35 km, could be allochthonous fragments of what was originally a single mafic body or separate mafic bodies intruded into the crust during the break-up of Rodinia in the Neoproterozoic, which was accompanied by considerable rifting. The manifestations of such magmatism are known in the NE part of the Volyno-Podolian Monocline, where the Vendian trap formation occurs at the surface.Сейсмический профиль TTZ-South с использованием преломленных и отраженных в закритической области преломленных волн, отработанный в 2018 г., пересекает юго-западный район Украины и юго-восточный регион Польши. Профиль TTZ-South был направлен на изучение структуры земной коры и верхней мантии Трансъевропейской шовной зоны (ТЕШЗ) и юго-западного сегмента Восточно-Европейского кратона (склона Украинского щита). Профиль длиной ~550 км (~230 км в Польше и ~320 км на западе Украины) является продолжением ранее реализованных проектов в Польше — профиля TTZ (1993 г.) и CEL03 (2000 г.). Глубинное сейсмическое зондирование по профилю TTZ-South, выполненное с использованием 320 сейсмических станций TEXAN и DATA-CUBE, позволило получить сейсмические записи высокого качества из одиннадцати пунктов взрыва (шесть в Украине и пять в Польше). В данной статье представлена упрощенная Р-скоростная модель, основанная на инверсии времен пробега первых вступлений Р-волн, построенная с использованием программы сейсмической томографии первых вступлений FAST. Полученное изображение представляет собой предварительную скоростную модель, которая состоит из осадочного слоя и кристаллической коры, включающей верхний, средний и нижний ее слои. Поверхность Мохо, аппроксимируемая изолинией 7,5 км/с, расположена на глубине 45—47 км в центральной части профиля, воздымаясь до 40 и 37 км в северной (Радом-Лысогорский блок в Польше) и южной (Волыно-Подольская моноклиналь в Украине) частях профиля соответственно. Особенностью скоростного разреза является ряд высокоскоростных тел, выявленных в диапазоне глубин 10—35 км. Аналогичные высокоскоростные тела ранее были обнаружены в коре Радом-Лысогорского блока. Тела, обнаруженные на глубине 10—35 км, могут быть аллохтонными фрагментами изначально единого массива основных пород или отдельными телами основного состава, внедрившимися в кору в неопротерозое во время раскола суперконтинета Родиния, который сопровождался мощным рифтогенезом. Проявления рифтогенного магматизма известны в северо-восточной части Волыно-Подольской моноклинали, где на поверхность выходят вендские трапы.Сейсмічний профіль TTZ-South з використанням заломлених і відбитих у за критичній зоні заломлених хвиль, відпрацьований у 2018 р., перетинає південно-західний район України і південно-східний регіон Польщі. Профіль TTZ-South був спрямований на вивчення структури земної кори і верхньої мантії Транс'єв ропейської шовної зони (ТЄШЗ) і південно-західного сегмента Східно-Європейського кратона (схила Українського щита). Профіль довжиною ~550 км (~230 км в Польщі і ~320 км на заході України) є продовженням раніше реалізованих проєктів у Польщі — профілю TTZ (1993 р.) і CEL03 (2000 р). Глибинне сейсмічне зондування за профілем TTZ-South, виконане з використанням 320 сейсмічних станцій TEXAN і DATA-CUBE, дало змогу отримати сейсмічні записи високої якості з одинадцяти пунктів вибуху (шість в Україні і п'ять у Польщі). У даній статті представлена спрощена Р-швидкісна модель, що базується на інверсії часів пробігу перших вступів Р-хвиль, побудована з використанням програми сейсмічної томографії перших вступів FAST. Отримане зображення являє собою попередню швидкісну модель, яка складається з осадового шару і кристалічної кори, що включає верхній, середній і нижній її шари. Поверхня Мохо, що апроксимується ізолінією 7,5 км/с, розташована на глибині 45—47 км у центральній частині профілю, здіймається до 40 і 37 км у північній (Радом-Лисогорський блок у Польщі) і південній (Волино-Подільська монокліналь в Україні) частинах профілю відповідно. Особливістю швидкісного розрізу є ряд високошвидкісних тіл, виявлених у діапазоні глибин 10—35 км. Подібні високошвидкісні тіла раніше були виявлені в корі Радом-Лисогірського блоку. Тіла, виявлені на глибині 10—35 км, можуть бути алохтонними фрагментами спочатку єдиного масиву основних порід або окремими тілами основного складу, що впровадилися в кору в неопротерозої під час розколу суперконтінета Родінія, який супроводжувався потужним рифтогенезом. Прояви рифтогенного магматизму відомі в північно-східній частині Волино-Подільської моноклінали, де на поверхню виходять вендські трапи

    Crustal and Upper Mantle Velocity Model along the DOBRE-4 Profile from North Dobruja to the Central Region of the Ukrainian Shield : 1. Seismic Data

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    For studying the structure of the lithosphere in southern Ukraine, wide-angle seismic studies that recorded the reflected and refracted waves were carried out under the DOBRE-4 project. The field works were conducted in October 2009. Thirteen chemical shot points spaced 35-50 km apart from each other were implemented with a charge weight varying from 600 to 1000 kg. Overall 230 recording stations with an interval of 2.5 km between them were used. The high quality of the obtained data allowed us to model the velocity section along the profile for P-and S-waves. Seismic modeling was carried out by two methods. Initially, trial-and-error ray tracing using the arrival times of the main reflected and refracted P-and S-phases was conducted. Next, the amplitudes of the recorded phases were analyzed by the finite-difference full waveform method. The resulting velocity model demonstrates a fairly homogeneous structure from the middle to lower crust both in the vertical and horizontal directions. A drastically different situation is observed in the upper crust, where the Vp velocities decrease upwards along the section from 6.35 km/s at a depth of 15-20 km to 5.9-5.8 km/s on the surface of the crystalline basement; in the Neoproterozoic and Paleozoic deposits, it diminishes from 5.15 to 3.80 km/s, and in the Mesozoic layers, it decreases from 2.70 to 2.30 km/s. The sub-crustal Vp gradually increases downwards from 6.50 to 6.7-6.8 km/s at the crustal base, which complicates the problem of separating the middle and lower crust. The Vp velocities above 6.80 km/s have not been revealed even in the lowermost part of the crust, in contrast to the similar profiles in the East European Platform. The Moho is clearly delineated by the velocity contrast of 1.3-1.7 km/s. The alternating pattern of the changes in the Moho depths corresponding to Moho undulations with a wavelength of about 150 km and the amplitude reaching 8 to 17 km is a peculiarity of the velocity model.Peer reviewe

    Lithospheric structure along wide-angle seismic profile GEORIFT 2013 in Pripyat–Dnieper–Donets Basin (Belarus and Ukraine)

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    The GEORIFT 2013 (GR'13) WARR (wide-angle reflection and refraction) experiment was carried out in 2013 in the territory of Belarus and Ukraine with broad international co-operation. The aim of the work is to study basin architecture and deep structure of the Pripyat-Dnieper-Donets Basin (PDDB), which is the deepest and best studied Palaeozoic rift basin in Europe. The PDDB is located in the southern part of the East European Craton (EEC) and crosses Sarmatia-one of the three segments of the EEC. The PDDB was formed by Late Devonian rifting associated with domal basement uplift and magmatism. The GR'13 extends in NW SE direction along the PDDB strike and crosses the Pripyat Trough (PT) and Dnieper Graben (DG) separated by the Bragin Uplift (BU) of the basement. The field acquisition along the GR'13 (of 670 km total length) involved 14 shots and recorders deployed every similar to 2.2 km for several shot points. The good quality of the data, with first arrivals visible up to 670 km for several shot points, allowed for construction of a velocity model extending to 80 km depth using ray-tracing modelling. The thickness of the sediments (Vp <6.0 km s(-1)) varies from 1-4 km in the PT, to 5 km in the NW part of the DG, to 10-13 km in the SE part of the profile. Below the DG, at similar to 330-530 km distance, we observed an upwarping of the lower crust (with Vp of similar to 7.1 km s(-1)) to 25 km depth that represents a rift pillow or mantle underplate. The Moho shallows southeastwards from similar to 47 km in the PT to 40-38 km in the DG with mantle velocities of 8.35 and similar to 8.25 km s(-1) in the PT and DG, respectively. A near-horizontal mantle discontinuity was found beneath BU (a transition zone from the PT to the DG) at the depth of 50-47 km. It dips to the depth of similar to 60 km at distances of 360-405 km, similar to the intersecting EUROBRIDGE'97 profile. The crust and upper mantle structure on the GR'13 may reflect varying intensity of rifting in the PDDB from a passive stage in the PT to active rifting in the DG. The absence of Moho uplift and relatively thick crystalline crust under the PT is explained by its tectonic position as a closing unit of the PDDB, with a gradual attenuation of rifting from the southeast to the northwest. The most active stage of rifting is evidenced in the DG by a shallower Moho and by a presence of a rift pillow caused by mafic and ultramafic intrusions during the active phase. The junction of the PT and the DG (the BU) locates just at its intersection with the NS regional tectonic zone Odessa-Gomel. Most likely, the 'blocking' effect of this zone did not allow for further propagation of active rifting to the NW.Peer reviewe

    Risk factors for anxiety and depression among pregnant women during COVID-19 pandemic-Results of a web-based multinational cross-sectional study

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    Objective To assess risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic using Mind-COVID, a prospective cross-sectional study that compares outcomes in middle-income economies and high-income economies. Methods A total of 7102 pregnant women from 12 high-income economies and nine middle-income economies were included. The web-based survey used two standardized instruments, General Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). Result Pregnant women in high-income economies reported higher PHQ-9 (0.18 standard deviation [SD], P < 0.001) and GAD-7 (0.08 SD, P = 0.005) scores than those living in middle-income economies. Multivariate regression analysis showed that increasing PHQ-9 and GAD-7 scales were associated with mental health problems during pregnancy and the need for psychiatric treatment before pregnancy. PHQ-9 was associated with a feeling of burden related to restrictions in social distancing, and access to leisure activities. GAD-7 scores were associated with a pregnancy-related complication, fear of adverse outcomes in children related to COVID-19, and feeling of burden related to finances. Conclusions According to this study, the imposed public health measures and hospital restrictions have left pregnant women more vulnerable during these difficult times. Adequate partner and family support during pregnancy and childbirth can be one of the most important protective factors against anxiety and depression, regardless of national economic status

    Moho depth across the Trans-European Suture Zone from P-and S-receiver functions

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    The Mohorovicic discontinuity, Moho for short, which marks the boundary between crust and mantle, is the main first-order structure within the lithosphere. Geodynamics and tectonic evolution determine its depth level and properties. Here, we present a map of the Moho in central Europe across the Teisseyre-Tornquist Zone, a region for which a number of previous studies are available. Our results are based on homogeneous and consistent processing of P- and S-receiver functions for the largest passive seismological data set in this region yet, consisting of more than 40 000 receiver functions from almost 500 station. Besides, we also provide new results for the crustal Vp/Vs ratio for the whole area. Our results are in good agreement with previous, more localized receiver function studies, as well as with the interpretation of seismic profiles, while at the same time resolving a higher level of detail than previous maps covering the area, for example regarding the Eifel Plume region, Rhine Graben and northern Alps. The close correspondence with the seismic data regarding crustal structure also increases confidence in use of the data in crustal corrections and the imaging of deeper structure, for which no independent seismic information is available. In addition to the pronounced, stepwise transition from crustal thicknesses of 30km in Phanerozoic Europe to more than 45 beneath the East European Craton, we can distinguish other terrane boundaries based on Moho depth as well as average crustal Vp/Vsratio and Moho phase amplitudes. The terranes with distinct crustal properties span a wide range of ages, from Palaeoproterozoic in Lithuania to Cenozoic in the Alps, reflecting the complex tectonic history of Europe. Crustal thickness and properties in the study area are also markedly influenced by tectonic overprinting, for example the formation of the Central European Basin System, and the European Cenozoic Rift System. In the areas affected by Cenozoic rifting and volcanism, thinning of the crust corresponds to lithospheric updoming reported in recent surface wave and S-receiver function studies, as expected for thermally induced deformation. The same correlation applies for crustal thickening, not only across the Trans-European Suture Zone, but also within the southern part of the Bohemian Massif. A high Poisson’s ratio of 0.27 is obtained for the craton, which is consistent with a thick mafic lower crust. In contrast, we typically find Poisson’s ratios around 0.25 for Phanerozoic Europe outside of deep sedimentary basins. Mapping of the thickness of the shallowest crustal layer, that is low-velocity sediments or weathered rock, indicates values in excess of 6km for the most pronounced basins in the study area, while thicknesses of less than 4km are found within the craton, central Germany and most of the Czech Republic.Peer reviewe

    The genomics of heart failure: design and rationale of the HERMES consortium

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    AIMS: The HERMES (HEart failure Molecular Epidemiology for Therapeutic targetS) consortium aims to identify the genomic and molecular basis of heart failure. METHODS AND RESULTS: The consortium currently includes 51 studies from 11 countries, including 68 157 heart failure cases and 949 888 controls, with data on heart failure events and prognosis. All studies collected biological samples and performed genome-wide genotyping of common genetic variants. The enrolment of subjects into participating studies ranged from 1948 to the present day, and the median follow-up following heart failure diagnosis ranged from 2 to 116 months. Forty-nine of 51 individual studies enrolled participants of both sexes; in these studies, participants with heart failure were predominantly male (34–90%). The mean age at diagnosis or ascertainment across all studies ranged from 54 to 84 years. Based on the aggregate sample, we estimated 80% power to genetic variant associations with risk of heart failure with an odds ratio of ≥1.10 for common variants (allele frequency ≥ 0.05) and ≥1.20 for low-frequency variants (allele frequency 0.01–0.05) at P < 5 × 10^{-8} under an additive genetic model. CONCLUSIONS: HERMES is a global collaboration aiming to (i) identify the genetic determinants of heart failure; (ii) generate insights into the causal pathways leading to heart failure and enable genetic approaches to target prioritization; and (iii) develop genomic tools for disease stratification and risk prediction
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