Some Implications of Outdoor Recreation Desires for Urban Redevelopment

Author Institution: Department of Geography, Miami UniversityThe significance of four attributes of outdoor recreation relative to a consideration of urban redevelopment forms the focus of this paper. Data on the public's desires for specific recreational facility qualities and activities and the socio-economic characteristics of households are used to develop implications for urban redevelopment policy. Some effects of household income level, car availability, and place of residence are examined as examples. Conclusions are based on a possible set of public responses and emphasize the need for a fuller appreciation of the role of outdoor recreation in policy determination

Tangible interfaces for tangible robots

Non

Casco

https://digitalcommons.library.umaine.edu/mmb-me/1344/thumbnail.jp

Safety of Food and Water Supplies in the Landscape of Changing Climate

In response to evolving environmental, production, and processing conditions, microbial communities have tremendous abilities to move toward increased diversity and fitness by various pathways such as vertical and horizontal gene transfer mechanisms, biofilm formation, and quorum sensin

The Threat of Antibiotic Resistance in Changing Climate

As the earliest form of life, microorganisms have elaborate mechanisms for adapting to changes in environmental conditions

Neutral doing: intended objects

This project takes the form of an investigation into the speculative object as proposed by Alain Robbe Grillet through his fictional writing and its use as a means for articulating the developments and propositions in my practice. The Object, which is considered through the dual statements in the title, is deployed and tested through examination and example to be considered as a viable and useful mechanism for the consideration of my studio work and thesis enquiry. Robbe Grillet’s Object, at the center of this enquiry, is considered through its material, physical, mute characteristics and impulses, and is tested against a selection of artist’s and writer’s enquiries that might be considered to be working with ‘the object’ with a degree of correlation and sympathy to Robbe Grillet’s intentions. The question begins with the establishment of figural indeterminacy of the object that is the result of Robbe Grillet’s neutralising and repetitive objectification. The implications of this strategy are then developed through notions of the fragment, and in particular, Georges Didi Huberman’s proposal of the Patch as an agitating necessity in a formal field. This question is then applied to the Mottled screen as presented by Proust and explored by Mieke Bal. These proposals are in turn questioned as viable approaches to engaging with, and the production of, artwork. In particular, whether it is possible to evolve a spatial dialectic which functions as both immediate source for an embodied experience and as a sign and symptom to be decoded. Is it feasible to generate space around the ‘object as fragment’, which becomes open and transformative through the viewers collaboration. In considering the use of the fragment as presented by Robbe Grillet as a structural and symbolic device in his writing I have developed a set of fragmentary propositions for the structure of the text to follow. These ‘fragment chapters’ are intended to elide or fold together as separate and collaborative elements. Under a series of chapter headings my intention is to explore sections and elements of the enquiry that use as starting points formal and pictorial manifestations which are then opened out into broader discussions. These debates loop back and across with the implication that they reflect the habit of description in Robbe Grillet’s writing

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts