790 research outputs found

    Moyo Vol. X N 2

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    Million, Chris. Editor\u27s Letter . 4. Kaczur, Erin. Why It Sucks to be Human: I Would Like to Change My Casing, Not My Underwear . 5. Dunson, Jim and Tom Hankinson. MoYummy: Our Staff Connoisseurs Hit the Spots That Hit the Spot . 6. Fisher, Dan. Happy, O Monk, Is Thy Shadow! A No Pluses, No Minuses Memory of a Spiritual Friend . 10. Reuss, Liz. Who is S/He? Leslie Feinberg Interview Inspires Introspection . 11. Marston, Jennifer. MoYo Millenium Picks: Ghandi Can Forget it . 12. Bungard, Chris. Pop The Cork on Ireland. Strictly No Drinking Stritly Ignored . 13. Wilson, Kalyn. Pagans in print: The Craft--So Much more Than Sabrina . 14. Mallinger, Adam. DU Press Release Revisited . 16. Zellner, Kelli. Denison University\u27s Campus Compact--Myth or Reality? DU\u27s Bubble, Burst . 17. Hankinson, Tom. Bureaucracy--Friend of the Common man. An Explication Rather Than an Expletive . 18. The TasyPaycheck. A Very Tasty Quiz: The Denison Social Hierarchy - Do You Cut it? 20. Mong, Derek. The Armpit Epiphany . 21. Curry, Kim. Hot Child in The City: An Unaccustomed look Back from a Big Apple Intern . 22. Million, Chris. Their Last Chance! 32. Kovach, Steve. Risk-y Business: Strategies for Getting More enjoyment Out of World Conquest . 34

    System Qualities Ontology, Tradespace and Affordability (SQOTA) Project Phase 5

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    Motivation and Context: One of the key elements of the SERC's research strategy is transforming the practice of systems engineering and associated management practices- "SE and Management Transformation (SEMT)." The Grand Challenge goal for SEMT is to transform the DoD community 's current systems engineering and management methods, processes, and tools (MPTs) and practices away from sequential, single stovepipe system, hardware-first ,document-driven, point- solution, acquisition-oriented approaches; and toward concurrent, portfolio and enterprise-oriented, hardware-software-human engineered, model-driven, set-based, full life cycle approaches.This material is based upon work supported, in whole or in part, by the U.S. Department of Defense through the Office of the Assistant Secretary of Defense for Research and Engineering (ASD(R&E)) under Contract H98230-08-D-0171 and HQ0034-13-D-0004 (TO 0060).This material is based upon work supported, in whole or in part, by the U.S. Department of Defense through the Office of the Assistant Secretary of Defense for Research and Engineering (ASD(R&E)) under Contract H98230-08-D-0171 and HQ0034-13-D-0004 (TO 0060)

    G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon.

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    BACKGROUND: Plasmodium vivax parasites are the predominant cause of malaria infections in the Brazilian Amazon. Infected individuals are treated with primaquine, which can induce haemolytic anaemia in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals and may lead to severe and fatal complications. This X-linked disorder is distributed globally and is caused by allelic variants with a geographical distribution that closely reflects populations exposed historically to endemic malaria. In Brazil, few studies have reported the frequency of G6PD deficiency (G6PDd) present in malaria-endemic areas. This is particularly important, as G6PDd screening is not currently performed before primaquine treatment. The aim of this study was to determine the prevalence of G6PDd in the region of Alto do Juruá, in the Western Brazilian Amazon, an area characterized by a high prevalence of P. vivax infection. METHODS: Five-hundred and sixteen male volunteers were screened for G6PDd using the fluorescence spot test (Beutler test) and CareStart™ G6PD Biosensor system. Demographic and clinical-epidemiological data were acquired through an individual interview. To assess the genetic basis of G6PDd, 24 SNPs were genotyped using the Kompetitive Allele Specific PCR assay. RESULTS: Twenty-three (4.5%) individuals were G6PDd. No association was found between G6PDd and the number of malaria cases. An increased risk of reported haemolysis symptoms and blood transfusions was evident among the G6PDd individuals. Twenty-two individuals had the G6PDd A(-) variant and one the G6PD A(+) variant. The Mediterranean variant was not present. Apart from one polymorphism, almost all SNPs were monomorphic or with low frequencies (0-0.04%). No differences were detected among ethnic groups. CONCLUSIONS: The data indicates that ~1/23 males from the Alto do Juruá could be G6PD deficient and at risk of haemolytic anaemia if treated with primaquine. G6PD A(-) is the most frequent deficiency allele in this population. These results concur with reported G6PDd in other regions in Brazil. Routine G6PDd screening to personalize primaquine administration should be considered, particularly as complete treatment of patients with vivax malaria using chloroquine and primaquine, is crucial for malaria elimination

    System Qualities Ontology, Tradespace and Affordability (SQOTA) Project – Phase 4

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    This task was proposed and established as a result of a pair of 2012 workshops sponsored by the DoD Engineered Resilient Systems technology priority area and by the SERC. The workshops focused on how best to strengthen DoD’s capabilities in dealing with its systems’ non-functional requirements, often also called system qualities, properties, levels of service, and –ilities. The term –ilities was often used during the workshops, and became the title of the resulting SERC research task: “ilities Tradespace and Affordability Project (iTAP).” As the project progressed, the term “ilities” often became a source of confusion, as in “Do your results include considerations of safety, security, resilience, etc., which don’t have “ility” in their names?” Also, as our ontology, methods, processes, and tools became of interest across the DoD and across international and standards communities, we found that the term “System Qualities” was most often used. As a result, we are changing the name of the project to “System Qualities Ontology, Tradespace, and Affordability (SQOTA).” Some of this year’s university reports still refer to the project as “iTAP.”This material is based upon work supported, in whole or in part, by the U.S. Department of Defense through the Office of the Assistant of Defense for Research and Engineering (ASD(R&E)) under Contract HQ0034-13-D-0004.This material is based upon work supported, in whole or in part, by the U.S. Department of Defense through the Office of the Assistant of Defense for Research and Engineering (ASD(R&E)) under Contract HQ0034-13-D-0004

    Towards a synthesized critique of neoliberal biodiversity conservation

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    During the last three decades, the arena of biodiversity conservation has largely aligned itself with the globally dominant political ideology of neoliberalism and associated governmentalities. Schemes such as payments for ecological services are promoted to reach the multiple ‘wins’ so desired: improved biodiversity conservation, economic development, (international) cooperation and poverty alleviation, amongst others. While critical scholarship with respect to understanding the linkages between neoliberalism, capitalism and the environment has a long tradition, a synthesized critique of neoliberal conservation - the ideology (and related practices) that the salvation of nature requires capitalist expansion - remains lacking. This paper aims to provide such a critique. We commence with the assertion that there has been a conflation between ‘economics’ and neoliberal ideology in conservation thinking and implementation. As a result, we argue, it becomes easier to distinguish the main problems that neoliberal win-win models pose for biodiversity conservation. These are framed around three points: the stimulation of contradictions; appropriation and misrepresentation and the disciplining of dissent. Inspired by Bruno Latour’s recent ‘compositionist manifesto’, the conclusion outlines some ideas for moving beyond critique
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