64 research outputs found

    High Current, High frequency ECRIS development program for LHC heavy ion beam application

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    A research program with the aim of producing pulsed currents with hitherto unequalled intensity of Pb27+, with length and repetition ratecompatible with those desired by CERN (1 mAe / 400 ms / 10 Hz in the context of future heavy ion collisions at LHC) is organised in acollaboration between CERN/GSI/CEA-Grenoble and IN2P3-ISNG.Two main experimental programs will be carried out : (i) tests with the LNS-Catania team on the SERSE superconducting source with a 28 GHzgyrotron, (ii) tests on a non-superconducting source (new source at Grenoble) with a 28 GHz gyrotron. For this purpose CEA/DRFMC hasborrowed from CEA a 28 GHz - 10 kW gyrotron transmitter.The project includes also the construction of a source body, by ISNG, with conventional coils and permanent magnets for working at the frequencyof about 28 GHz and biased up to 60 kV. This source called PHOENIX will run on a test bench at ISN. PHOENIX is an improvement of thepresent ECR4-14.5 GHz/CERN source, having a mirror ratio R=2 at 14.5 GHz, and R=1.7 at 28 GHz (possibly reaching 2.1 T on the axis of thesource), and with a plasma volume up to 2.5 larger.Experiments at 28 GHz will be performed on the SERSE source in Catania at INFN/LNS where both the axial and the hexapolar fields will bevaried so that the mirror ratio is continuously varied up to R=1.6 ; the SERSE source will be also operated at lower magnetic fields such as thosewhich can be produced by conventional magnets (less than 2 T axial field at injection - far from the 28 GHz High-B mode)

    Making science at home: visual displays of space science and nuclear physics at the Science Museum and on television in postwar Britain

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    The public presentation of science and technology in postwar Britain remains a field open to exploration. Current scholarship on the topic is growing but still tends to concentrate on the written word, thus making theorizing, at this stage, difficult. This paper is an attempt to expand the literature through two case studies that compare and synthesize displays of scientific and technological knowledge in two visual media, the Science Museum and television, in the 1950s and 1960s. The topics of these case studies are space exploration and nuclear energy. The thesis this paper explores is that both media fleshed out strategies of displays based on the use of categories from everyday life. As a result, outcomes of large-scale public scientific and technological undertakings were interwoven within audiences’ daily life experiences, thus appearing ordinary rather than extraordinary. This use of symbols and values drawn from private life worked to alleviate fears of risk associated with these new fields of technological exploration and at the same time give them widespread currency in the public sphere

    Simultaneous multiple breath washout and oxygen-enhanced magnetic resonance imaging in healthy adults.

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    Lung function testing and lung imaging are commonly used techniques to monitor respiratory diseases, such as cystic fibrosis (CF). The nitrogen (N2) multiple-breath washout technique (MBW) has been shown to detect ventilation inhomogeneity in CF, but the underlying pathophysiological processes that are altered are often unclear. Dynamic oxygen-enhanced magnetic resonance imaging (OE-MRI) could potentially be performed simultaneously with MBW because both techniques require breathing of 100% oxygen (O2) and may allow for visualisation of alterations underlying impaired MBW outcomes. However, simultaneous MBW and OE-MRI has never been assessed, potentially as it requires a magnetic resonance (MR) compatible MBW equipment. In this pilot study, we assessed whether MBW and OE-MRI can be performed simultaneously using a commercial MBW device that has been modified to be MR-compatible. We performed simultaneous measurements in five healthy volunteers aged 25-35 years. We obtained O2 and N2 concentrations from both techniques, and generated O2 wash-in time constant and N2 washout maps from OE-MRI data. We obtained good quality simultaneous measurements in two healthy volunteers due to technical challenges related to the MBW equipment and poor tolerance. Oxygen and N2 concentrations from both techniques, as well as O2 wash-in time constant maps and N2 washout maps could be obtained, suggesting that simultaneous measurements may have the potential to allow for comparison and visualization of regional differences in ventilation underlying impaired MBW outcomes. Simultaneous MBW and OE-MRI measurements can be performed with a modified MBW device and may help to understand MBW outcomes, but the measurements are challenging and have poor feasibility

    In Vivo Methods for the Assessment of Topical Drug Bioavailability

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    This paper reviews some current methods for the in vivo assessment of local cutaneous bioavailability in humans after topical drug application. After an introduction discussing the importance of local drug bioavailability assessment and the limitations of model-based predictions, the focus turns to the relevance of experimental studies. The available techniques are then reviewed in detail, with particular emphasis on the tape stripping and microdialysis methodologies. Other less developed techniques, including the skin biopsy, suction blister, follicle removal and confocal Raman spectroscopy techniques are also described

    Book Reviews; Reminiscence and Re-Creation in Contemporary American fiction by Stacey Olster

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    American Literature -- December 1990 -- pages 737-738

    Sion, Petit-Chasseur (Neolithic-Bronze Age): Geography and Culture

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    The canton of Valais contains one of the most important Swiss Neolithic sites: Petit-Chasseur in Sion. While this site is already internationally renowned for its megalithic necropolis dating from the Late Neolithic to the Early Bronze Age as well as for its beautiful anthropomorphic stelae, it also has occupation levels dating to the Middle Neolithic and burial sites of the Second Iron Age
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