A bibliography of published information relevant to fire toxicity

A bibliography containing 883 references in the field of fire toxicity is presented to assist in literature searches to help reduce human fire hazards

Dynamic acoustic field activated cell separation (DAFACS)

Advances in diagnostics, cell and stem cell technologies drive the development of application-specific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for highthroughput, label-free, high recovery, cell and particle separation and isolation in regenerative medicine. Here, we demonstrate a novel approach utilizing a dynamic acoustic field that is capable of separating an arbitrary size range of cells. We first demonstrate the method for the separation of particles with different diameters between 6 and 45 μm and secondly particles of different densities in a heterogeneous medium. The dynamic acoustic field is then used to separate dorsal root ganglion cells. The shearless, label-free and low damage characteristics make this method of manipulation particularly suited for biological applications. Advantages of using a dynamic acoustic field for the separation of cells include its inherent safety and biocompatibility, the possibility to operate over large distances (centimetres), high purity (ratio of particle population, up to 100%), and high efficiency (ratio of separated particles over total number of particles to separate, up to 100%)

Paraoxonase gene polymorphisms and haplotype analysis in a stroke population

Peer reviewedPublisher PD

The cooling rate of neutron stars after thermonuclear shell flashes

Thermonuclear shell flashes on neutron stars are detected as bright X-ray bursts. Traditionally, their decay is modeled with an exponential function. However, this is not what theory predicts. The expected functional form for luminosities below the Eddington limit, at times when there is no significant nuclear burning, is a power law. We tested the exponential and power-law functional forms against the best data available: bursts measured with the high-throughput Proportional Counter Array (PCA) on board the Rossi X-ray Timing Explorer. We selected a sample of 35 'clean' and ordinary (i.e., shorter than a few minutes) bursts from 14 different neutron stars that 1) show a large dynamic range in luminosity, 2) are the least affected by disturbances by the accretion disk and 3) lack prolonged nuclear burning through the rp-process. We find indeed that for every burst a power law is a better description than an exponential function. We also find that the decay index is steep, 1.8 on average, and different for every burst. This may be explained by contributions from degenerate electrons and photons to the specific heat capacity of the ignited layer and by deviations from the Stefan-Boltzmann law due to changes in the opacity with density and temperature. Detailed verification of this explanation yields inconclusive results. While the values for the decay index are consistent, changes of it with the burst time scale, as a proxy of ignition depth, and with time are not supported by model calculations.Comment: 10 pages, 7 figures, recommended for publication in A&

Monolithic Implementation of a Planar Gunn Diode and a pHEMT

No abstract available

Boosting clinical performance: The impact of enhanced final year placements.

BACKGROUND: This study follows on from a study that investigated how to develop effective final year medical student assistantship placements, using multidisciplinary clinical teams in planning and delivery. AIMS: This study assessed the effects on objective structured clinical examination (OSCE) performance of the in-course enhanced "super-assistantship" placement introduced to a randomly selected sample of 2013-14 final year medical students at Leeds medical school. METHODS: Quantitative data analysis was used to compare the global grades of OSCE stations between students who undertook this placement against those who did not. RESULTS: There was a small overall improvement in the "super-assistantship" student scores across the whole assessment (effect size = 0.085). "Pre-op Capacity", "Admissions Prescribing" and "Hip Pain" stations had small-medium effect sizes (0.226, 0.215, and 0.214) in favor of the intervention group. Other stations had small effect sizes (0.107-0.191), mostly in favor of the intervention group. CONCLUSIONS: The "super-assistantship" experience characterized by increasing student responsibility on placement can help to improve competence and confidence in clinical decision-making "in a simulated environment". The clinical environment and multidisciplinary team must be ready and supported to provide these opportunities effectively. Further in-course opportunities for increasing final year student responsibility should be developed

Interactive manipulation of microparticles in an octagonal sonotweezer

An ultrasonic device for micro-patterning and precision manipulation of micrometre-scale particles is demonstrated. The device is formed using eight piezoelectric transducers shaped into an octagonal cavity. By exciting combinations of transducers simultaneously, with a controlled phase delay between them, different acoustic landscapes can be created, patterning micro-particles into lines, squares, and more complex shapes. When operated with all eight transducers the device can, with appropriate phase control, manipulate the two dimensional acoustic pressure gradient; it thus has the ability to position and translate a single tweezing zone to different locations on a surface in a precise and programmable manner

Mitigation of Moral Hazard and Adverse Selection in Venture Capital Financing: The Influence of the Country’s Institutional Setting

A venture capitalist (VC) needs to trade off benefits and costs when attempting to mitigate agency problems in their investor-investee relationship. We argue that signals of ventures complement the VC’s capacity to screen and conduct a due diligence during the pre-investment phase, but its attractiveness may diminish in institutional settings supporting greater transparency. Similarly, whereas a VC may opt for contractual covenants to curb potential opportunism by ventures in the post-investment phase, this may only be effective in settings supportive of shareholder rights enforcement. Using an international sample of VC contracts, our study finds broad support for these conjectures. It delineates theoretical and practical implications for how investors can best deploy their capital in different institutional settings whilst nurturing their relationships with entrepreneurs