Experimentally estimated dead space for GaAs and InP based planar Gunn diodes

The authors would like to thank the staff of the James Watt Nanofabrication Centre at the University of Glasgow for help in fabricating the devices which is reported in this paper. ‘Part of this work was supported by ESPRC through EP/H011862/ 1, and EP/H012966/1.Peer reviewedPublisher PD

Dynamic acoustic field activated cell separation (DAFACS)

Advances in diagnostics, cell and stem cell technologies drive the development of application-specific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for highthroughput, label-free, high recovery, cell and particle separation and isolation in regenerative medicine. Here, we demonstrate a novel approach utilizing a dynamic acoustic field that is capable of separating an arbitrary size range of cells. We first demonstrate the method for the separation of particles with different diameters between 6 and 45 μm and secondly particles of different densities in a heterogeneous medium. The dynamic acoustic field is then used to separate dorsal root ganglion cells. The shearless, label-free and low damage characteristics make this method of manipulation particularly suited for biological applications. Advantages of using a dynamic acoustic field for the separation of cells include its inherent safety and biocompatibility, the possibility to operate over large distances (centimetres), high purity (ratio of particle population, up to 100%), and high efficiency (ratio of separated particles over total number of particles to separate, up to 100%)

Theory of cooling neutron stars versus observations

We review current state of neutron star cooling theory and discuss the prospects to constrain the equation of state, neutrino emission and superfluid properties of neutron star cores by comparing the cooling theory with observations of thermal radiation from isolated neutron stars.Comment: 9 pages, 4 figures, 3 tables, to appear in the proceedings of "40 Years of Pulsars" held in Montreal, Canada, August 12-17, 2007, eds. C. Bassa, Z. Wang, A. Cumming, V. Kaspi, AIP, in press (v.2 - minor bibliography corrections

Boosting clinical performance: The impact of enhanced final year placements.

BACKGROUND: This study follows on from a study that investigated how to develop effective final year medical student assistantship placements, using multidisciplinary clinical teams in planning and delivery. AIMS: This study assessed the effects on objective structured clinical examination (OSCE) performance of the in-course enhanced "super-assistantship" placement introduced to a randomly selected sample of 2013-14 final year medical students at Leeds medical school. METHODS: Quantitative data analysis was used to compare the global grades of OSCE stations between students who undertook this placement against those who did not. RESULTS: There was a small overall improvement in the "super-assistantship" student scores across the whole assessment (effect size = 0.085). "Pre-op Capacity", "Admissions Prescribing" and "Hip Pain" stations had small-medium effect sizes (0.226, 0.215, and 0.214) in favor of the intervention group. Other stations had small effect sizes (0.107-0.191), mostly in favor of the intervention group. CONCLUSIONS: The "super-assistantship" experience characterized by increasing student responsibility on placement can help to improve competence and confidence in clinical decision-making "in a simulated environment". The clinical environment and multidisciplinary team must be ready and supported to provide these opportunities effectively. Further in-course opportunities for increasing final year student responsibility should be developed

Carbon Flashes in the Heavy Element Ocean on Accreting Neutron Stars

We show that burning of a small mass fraction of carbon in a neutron star ocean is thermally unstable at low accumulated masses when the ocean contains heavy ashes from the hydrogen burning rapid proton (rp) process. The key to early unstable ignition is the low thermal conductivity of a heavy element ocean. The instability requires accretion rates in excess of one-tenth the Eddington limit when the carbon mass fraction is 0.1 or less. The unstable flashes release 10^{42} to 10^{43} ergs over hours to days, and are likely the cause of the recently discovered large Type I X-ray bursts (so-called ``superbursts'') from six Galactic low mass X-ray binaries. In addition to explaining the energetics, recurrence times, and durations of the superbursts, these mixed carbon/heavy element flashes have an accretion rate dependence of unstable burning similar to that observed. Though the instability is present at accretion rates near Eddington, there is less contrast with the accretion luminosity there, explaining why most detections are made at accretion rates between 0.1 and 0.3 Eddington. Future comparisons of time dependent calculations with observations will provide new insights into the rp process.Comment: Submitted to Astrophysical Journal Letters (6 pages, 3 figures

Mitigation of Moral Hazard and Adverse Selection in Venture Capital Financing: The Influence of the Country’s Institutional Setting

A venture capitalist (VC) needs to trade off benefits and costs when attempting to mitigate agency problems in their investor-investee relationship. We argue that signals of ventures complement the VC’s capacity to screen and conduct a due diligence during the pre-investment phase, but its attractiveness may diminish in institutional settings supporting greater transparency. Similarly, whereas a VC may opt for contractual covenants to curb potential opportunism by ventures in the post-investment phase, this may only be effective in settings supportive of shareholder rights enforcement. Using an international sample of VC contracts, our study finds broad support for these conjectures. It delineates theoretical and practical implications for how investors can best deploy their capital in different institutional settings whilst nurturing their relationships with entrepreneurs

Micro-cooler Enhancements by Barrier Interface Analysis

Peer reviewedPublisher PD

Most people keep their word rather than their money

Promises are crucial for human cooperation because they allow people to enter into voluntary commitments about future behavior. Here we present a novel, fully incentivized paradigm to measure voluntary and costly promise-keeping in the absence of external sanctions. We found across three studies (N = 4,453) that the majority of participants (61%–98%) kept their promises to pay back a specified amount of a monetary endowment, and most justified their decisions by referring to obligations and norms. Varying promise elicitation methods (Study 1a) and manipulating stake sizes (Study 2a) had negligible effects. Simultaneously, when others estimated promise-keeping rates (using two different estimation methods), they systematically underestimated promise-keeping by up to 40% (Studies 1b and 2b). Additional robustness checks to reduce potential reputational concerns and possible demand effects revealed that the majority of people still kept their word (Study 3). Promises have a strong normative power and binding effect on behavior. Nevertheless, people appear to pessimistically underestimate the power of others’ promises. This behavior–estimation gap may prevent efficient coordination and cooperation

The first Suzaku observation of SGR 1806-20

The soft gamma-ray repeater SGR 1806-20 has been attracting a lot of attention owing to the fact that in December 2004 it emitted the most powerful giant flare ever observed. Here we present the results of the first Suzaku observation of SGR 1806-20, that seems to have reached a state characterized by a flux close to the pre-flare level and by a relatively soft spectrum. Despite this, the source remained quite active, as testified by several short bursts observed by Suzaku. We discuss the broadband spectral properties of SGR 1806-20 in the context of the magnetar model, considering its recent theoretical developments.Comment: 3 pages, 1 figure. Proceedings of the conference "40 Years of Pulsars, Millisecond Pulsars, Magnetars and More", Montreal, August 12-17 2007. AIP, in pres

A 610-MHz Galactic Plane Pulsar Search with the Giant Meterwave Radio Telescope

We report on the discovery of three new pulsars in the first blind survey of the north Galactic plane (45 < l < 135 ; |b| < 1) with the Giant Meterwave Radio telescope (GMRT) at an intermediate frequency of 610 MHz. The timing parameters, obtained in follow up observations with the Lovell Telescope at Jodrell Bank Observatory and the GMRT, are presented.Comment: 2 pages, 1 figure, to be published in conference proceedings of "40 years of pulsars ..", replaced figure