145 research outputs found

    A Statistical Study on Photospheric Magnetic Nonpotentiality of Active Regions and Its Relationship with Flares during Solar Cycles 22-23

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    A statistical study is carried out on the photospheric magnetic nonpotentiality in solar active regions and its relationship with associated flares. We select 2173 photospheric vector magnetograms from 1106 active regions observed by the Solar Magnetic Field Telescope at Huairou Solar Observing Station, National Astronomical Observatories of China, in the period of 1988-2008, which covers most of the 22nd and 23rd solar cycles. We have computed the mean planar magnetic shear angle (\bar{\Delta\phi}), mean shear angle of the vector magnetic field (\bar{\Delta\psi}), mean absolute vertical current density (\bar{|J_{z}|}), mean absolute current helicity density (\bar{|h_{c}|}), absolute twist parameter (|\alpha_{av}|), mean free magnetic energy density (\bar{\rho_{free}}), effective distance of the longitudinal magnetic field (d_{E}), and modified effective distance (d_{Em}) of each photospheric vector magnetogram. Parameters \bar{|h_{c}|}, \bar{\rho_{free}}, and d_{Em} show higher correlation with the evolution of the solar cycle. The Pearson linear correlation coefficients between these three parameters and the yearly mean sunspot number are all larger than 0.59. Parameters \bar{\Delta\phi}, \bar{\Delta\psi}, \bar{|J_{z}|}, |\alpha_{av}|, and d_{E} show only weak correlations with the solar cycle, though the nonpotentiality and the complexity of active regions are greater in the activity maximum periods than in the minimum periods. All of the eight parameters show positive correlations with the flare productivity of active regions, and the combination of different nonpotentiality parameters may be effective in predicting the flaring probability of active regions.Comment: 20 pages, 5 figures, 4 tables, accepted for publication in Solar Physic

    Myogenic vasoconstriction requires canonical Gq/11 signaling of the angiotensin II type 1a receptor in the murine vasculature

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    BACKGROUND: The myogenic response is an inherent vasoconstrictive property of resistance arteries to keep blood flow constant in response to increases in intravascular pressure. Angiotensin II (Ang II) type 1 receptors (AT1R) are broadly distributed, mechanoactivated receptors, which have been proposed to transduce myogenic vasoconstriction. However, the AT1R subtype(s) involved and their downstream G protein- and β-arrestin-mediated signaling pathways are still elusive. OBJECTIVE: To characterize the function of AT1aR and AT1bR in the regulation of the myogenic response of resistance size arteries and possible downstream signaling cascades mediated by G(q/11) and/or β-arrestins. METHODS: We used Agtr1a(-/-), Agtr1b(-/-) and tamoxifen-inducible smooth muscle-specific AT1aR knockout mice (SM-Agtr1a mice). FR900359, [Sar1, Ile4, Ile8] Ang II (SII) and TRV120055 were used as selective G(q/11) protein inhibitor and biased agonists to activate non-canonical β-arrestin and canonical G(q/11) signaling of the AT1R, respectively. RESULTS: Myogenic and Ang II-induced vasoconstrictions were diminished in the perfused renal vasculature of Agtr1a(-/-) and SM-Agtr1a mice. Similar results were observed in isolated pressurized mesenteric and cerebral arteries. Myogenic tone and Ang II-induced vasoconstrictions were normal in arteries from Agtr1b(-/-) mice. The G(q/11) blocker FR900359 decreased myogenic tone and Ang II vasoconstrictions while selective biased targeting of AT1R β-arrestin signaling pathways had no effects. CONCLUSION: The present study demonstrates that myogenic arterial constriction requires G(q/11)-dependent signaling pathways of mechanoactivated AT1aR but not G protein-independent, noncanonical alternative signaling pathways in the murine mesenteric, cerebral and renal circulation

    Steamed panax notoginseng and its saponins inhibit the migration and induce the apoptosis of neutrophils in a zebrafish tail-fin amputation model

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    Panax notoginseng (PN) is a Chinese medicinal herb that is traditionally used to treat inflammation and immune-related diseases. Its major active constituents are saponins, the types and levels of which can be changed in the process of steaming. These differences in saponins are causally relevant to the differences in the therapeutic efficacies of raw and steamed PN. In this study, we have prepared the extracts of steamed PN (SPNE) with 70% ethanol and investigated their immunomodulatory effect using a zebrafish tail-fin amputation model. A fingerprint-effect relationship analysis was performed to uncover active constituents of SPNE samples related to the inhibitory effect on neutrophil number. The results showed that SPNE significantly inhibited the neutrophil number at the amputation site of zebrafish larvae. And SPNE extracts steamed at higher temperatures and for longer time periods showed a stronger inhibitory effect. Ginsenosides Rh-1, Rk(3), Rh-4, 20(S)-Rg(3), and 20(R)-Rg(3), of which the levels were increased along with the duration of steaming, were found to be the major active constituents contributing to the neutrophil-inhibiting effect of SPNE. By additionally investigating the number of neutrophils in the entire tail of zebrafish larvae and performing TUNEL assays, we found that the decreased number of neutrophils at the amputation site was due to both the inhibition of their migration and apoptosis-inducing effects of the ginsenosides in SPNE on neutrophils. Among them, Rh-1 and 20(R)-Rg(3) did not affect the number of neutrophils at the entire tail, suggesting that they only inhibit the migration of neutrophils. In contrast, ginsenosides Rk(3), Rh-4, 20(S)-Rg(3), and SPNE did not only inhibit the migration of neutrophils but also promoted neutrophilic cell death. In conclusion, this study sheds light on how SPNE, in particular the ginsenosides it contains, plays a role in immune modulation.Animal science

    Measurements of J/psi Decays into 2(pi+pi-)eta and 3(pi+pi-)eta

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    Based on a sample of 5.8X 10^7 J/psi events taken with the BESII detector, the branching fractions of J/psi--> 2(pi+pi-)eta and J/psi-->3(pi+pi-)eta are measured for the first time to be (2.26+-0.08+-0.27)X10^{-3} and (7.24+-0.96+-1.11)X10^{-4}, respectively.Comment: 11 pages, 6 figure

    BESII Detector Simulation

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    A Monte Carlo program based on Geant3 has been developed for BESII detector simulation. The organization of the program is outlined, and the digitization procedure for simulating the response of various sub-detectors is described. Comparisons with data show that the performance of the program is generally satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM

    The σ\sigma pole in J/ψωπ+πJ/\psi \to \omega \pi^+ \pi^-

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    Using a sample of 58 million J/ψJ/\psi events recorded in the BESII detector, the decay J/ψωπ+πJ/\psi \to \omega \pi^+ \pi^- is studied. There are conspicuous ωf2(1270)\omega f_2(1270) and b1(1235)πb_1(1235)\pi signals. At low ππ\pi \pi mass, a large broad peak due to the σ\sigma is observed, and its pole position is determined to be (541±39)(541 \pm 39) - ii (252±42)(252 \pm 42) MeV from the mean of six analyses. The errors are dominated by the systematic errors.Comment: 15 pages, 6 figures, submitted to PL

    Measurements of the Mass and Full-Width of the ηc\eta_c Meson

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    In a sample of 58 million J/ψJ/\psi events collected with the BES II detector, the process J/ψγηc\psi\to\gamma\eta_c is observed in five different decay channels: γK+Kπ+π\gamma K^+K^-\pi^+\pi^-, γπ+ππ+π\gamma\pi^+\pi^-\pi^+\pi^-, γK±KS0π\gamma K^\pm K^0_S \pi^\mp (with KS0π+πK^0_S\to\pi^+\pi^-), γϕϕ\gamma \phi\phi (with ϕK+K\phi\to K^+K^-) and γppˉ\gamma p\bar{p}. From a combined fit of all five channels, we determine the mass and full-width of ηc\eta_c to be mηc=2977.5±1.0(stat.)±1.2(syst.)m_{\eta_c}=2977.5\pm1.0 ({stat.})\pm1.2 ({syst.}) MeV/c2c^2 and Γηc=17.0±3.7(stat.)±7.4(syst.)\Gamma_{\eta_c} = 17.0\pm3.7 ({stat.})\pm7.4 ({syst.}) MeV/c2c^2.Comment: 9 pages, 2 figures and 4 table. Submitted to Phys. Lett.

    Search for the Lepton Flavor Violation Processes J/ψJ/\psi \to μτ\mu\tau and eτe\tau

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    The lepton flavor violation processes J/ψμτJ/\psi \to \mu\tau and eτe\tau are searched for using a sample of 5.8×107\times 10^7 J/ψJ/\psi events collected with the BESII detector. Zero and one candidate events, consistent with the estimated background, are observed in J/ψμτ,τeνˉeντJ/\psi \to \mu\tau, \tau\to e\bar\nu_e\nu_{\tau} and J/ψeτ,τμνˉμντJ/\psi\to e\tau, \tau\to\mu\bar\nu_{\mu}\nu_{\tau} decays, respectively. Upper limits on the branching ratios are determined to be Br(J/ψμτ)<2.0×106Br(J/\psi\to\mu\tau)<2.0 \times 10^{-6} and Br(J/ψeτ)<8.3×106Br(J/\psi \to e\tau) < 8.3 \times10^{-6} at the 90% confidence level (C.L.).Comment: 9 pages, 2 figure
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