Programa Pensión 65 y condiciones de vida de los usuarios del centro poblado Carmen Alto, Nuevo Imperial- Cañete, año 2019.

El objetivo de este trabajo de investigación fue titulada “Programa Pensión 65 y condiciones de vida de los usuarios del centro poblado Carmen Alto, Nuevo Imperial- Cañete, año 2019”, fue una investigación de tipo correlacional, que utilizó el diseño descriptivo. Trabajó con una muestra de 87 beneficiarios. El estudio comprueba que existe correlación estadísticamente significativa de 0,850; por lo que las variables se relacionan de manera lineal. Considerando el coeficiente de determinación, se tiene que las condiciones de vida de los usuarios están determinadas en un 72,2% por el Programa Pensión 65 del centro poblado Carmen Alto, Nuevo Imperial- Cañete, durante el año 2019.The objective of this research work was entitled "Pension 65 Program and living conditions of the users of the Carmen Alto populated center, Nuevo Imperial-Cañete, year 2019", it was a correlational type research, which used the descriptive design. He worked with a sample of 87 beneficiaries. The study confirms that there is a correlation statistically significant of 0.850; So the variables are related in a way linear. Considering the coefficient of determination, we have that the conditions of 72.2% of the life of the users are determined by the Pension 65 Program of the Carmen Alto populated center, Nuevo Imperial- Cañete, during the year 2019.ChosicaEscuela de Posgrad

Políticas de gestión y la responsabilidad social en el Hospital La Caleta de Chimbote - 2016

El propósito del estudio es determinar las políticas de gestión administrativa para mejorar la responsabilidad social en el hospital La Caleta de Chimbote; es una investigación básica, descriptiva de diseño no experimental de carácter transaccional. La población está constituida por 26 directivos de las diversas áreas administrativas del hospital y para medir la satisfacción de los usuarios, la muestra es de 384, se utilizó la fórmula para población infinita al 95% de confianza y 0.05 de error; se utilizó la técnica de la encuesta a los directivos y a usuarios. El hospital La Caleta no cuenta con políticas formales y definidas de responsabilidad social ni certificación de calidad, no se prioriza proveedores con buena conducta ambiental, no patrocina investigación y tecnología; no posee sistemas internos de comunicación externa para responder a los impactos del entorno. La satisfacción de los usuarios es: 64% satisfecho y 36 % de insatisfacción. Las principales políticas de gestión de RS son: promover la gestión basada en planificación para la toma de decisiones y de control; priorizar acciones y prácticas de bioseguridad y manejo adecuado de desechos peligrosos; promover el cumplimiento de derechos y deberes de funcionarios, en ambientes de pleno respeto y profesionalismo de cargos, actualización, entrenamiento y formación permanente de sus colaboradores y promover el uso eficiente de sistemas computacionales y de transparencia por internet.Trabajo de investigació

Responsabilidad social y comportamiento organizacional en la gerencia de administración - Municipalidad Provincial Del Santa - 2017

La presente investigación analiza las políticas de responsabilidad social y sus efectos en el comportamiento organizacional en la Gerencia de Administración de la Municipalidad Provincial de Santa; es una investigación básica y corresponde a una investigación no experimental, de carácter transaccional descriptiva, la recolección de datos se realizó en un solo momento en el tiempo. La población fue de 48 colaboradores; entre los hallazgos tenemos: sobre políticas organizativas, en un 54.10% la adaptación y gestión del cambio e innovación institucional contribuyen a mejorar el desempeño laboral en los puestos de trabajo; en políticas de recursos humano, entre los riesgos laborales la principal causa de ausentismo es: a).-Las nuevas formas de contratación en un 41.70%, continúan, b).- Inestabilidad en los puestos de trabajo en un 27.00%, c).- Enfermedades físicas en un 16.70% y d).-Aumento de volumen de trabajo en un 14.60%; respecto a políticas ambientales, en un 62.50%, algunas veces la organización adopta mecanismos de conciliación familiar y laboral socialmente responsable dirigido a establecer un clima de satisfacción laboral. El comportamiento organizacional es lo que hacen los trabajadores en la municipalidad y cómo ese comportamiento afecta el rendimiento de la misma. Relacionado a comportamiento individual, en un 93.80% la institución debería poner en práctica programas que promuevan la flexibilidad laboral para disminuir el ausentismo y rotación de sus colaboradores; el comportamiento grupal es el comportamiento que tienen las personas al estar en contacto con otras, en un 93.70% la municipalidad no utiliza sus programas de comunicación y de marketing para promover, valores, relaciones entre las personas y temas de responsabilidad social en los equipos de trabajo y comunidad; sobre el sistema organizacional considerado el nivel superior o estratégico; en un 45.90% es adecuada la estructura orgánica y organigrama de la Dirección de Administración de la municipalidad y en un 43.80% se han implementado estrategias de responsabilidad interna que promueven: la TICs, metas, procesos, funciones, puestos de trabajo, políticas y normas; en beneficio institucional y de la comunidad.Trabajo de investigació

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Eficacia del sistema de control interno en contrataciones de bienes y servicios del estado en la unidad de logística del hospital la caleta de chimbote

La presente tesis denominada: EFICACIA DEL SISTEMA DE CONTROL INTERNO EN CONTRATACIONES DE BIENES Y SERVICIOS DEL ESTADO EN LA UNIDAD DE LOGÍSTICA DEL HOSPITAL LA CALETA DE CHIMBOTE, es de interés para el autor y una necesidad latente en este nosocomio para el cumplimiento de la función social que le compete, significándose que el paciente es el eje principal en la función hospitalaria, la aplicación del control gubernamental debe estar orientado a contribuir a la efectividad de las contrataciones del Estado y se cumpla con la normatividad aplicable. Un eficaz Sistema de Control Interno (S.C.I) es fundamental para asegurar el cumplimiento de los Planes Anuales de Contrataciones de Bienes y Servicios del Estado, debido a que ambos sistemas integrados permiten tomar decisiones correctas en el largo plazo, mediano plazo y corto plazo orientado al día a día. En el presente estudio utilizamos el método transeccional descriptivo. Cuya muestra estuvo constituida por 27 trabajadores que participaron en procesos de contrataciones de bienes y servicios en el año 2010. Los resultados del presente estudio permiten establecer que en promedio de 73.16% no se aplicó el S.C.I. a los procesos de las contrataciones de bienes y servicios del Estado en la Unidad de Logística del Hospital La Caleta de Chimbote; entre las principales causas de esta brecha son: no se socializó el S.C.I. y los procesos de contrataciones del Estado, el paradigma predominante se expresa en que la gestión del control debe estar en manos solo de profesionales especializados, no se priorizaron los riesgos, se incumplió la normatividad sobre la materia, no se invirtió en capacitación del talento humano, débil accionar del Órgano de Control Institucional, corrupción o falta de ética, carencia de controles internos en la Unidad de Logística para el seguimiento y evaluación de la gestión de los procesos de contrataciones de bienes y servicios. Estas situaciones también ponen en riesgo la gestión de los recursos a nivel de la entidad, la eficacia y eficiencia de las operaciones, la confiabilidad de la información financiera y el cumplimiento de las leyes, reglamentos y políticas. Ante esta problemática se propone un sistema de control interno integral, coherente y eficaz aplicable a las contrataciones de bienes y servicios, elaborada respetando los lineamientos y normatividad legal sobre la materia, la misma que debe implementarse progresivamente, previa capacitación y socialización del potencial humano. En el diseño de dicha propuesta se siguieron cuatro fases denominadas: planificación, ejecución, evaluación e información. El proceso de implementación del sistema de control interno propuesto se materializará en la medida que se cuente con el completo compromiso y apoyo de los más altos niveles de la administración y el esfuerzo de los empleados de la entidad; específicamente de los funcionarios y servidores del órgano encargado de las contrataciones de la Entidad que, en razón de sus funciones intervienen directamente en alguna de las fases de contratación.This thesis entitled: EFFECTIVENESS OF INTERNAL CONTROL IN GOODS AND SERVICES CONTRACTS OF STATE IN THE HOSPITAL LOGISTICS UNIT OF THE COVE CHIMBOTE is of interest to the author and a latent need in the hospital for the performance of the function that social responsibility, signifying that the patient is the main function in the hospital, the application of government control must be designed to contribute to the effectiveness of state contracts and compliance with applicable regulations. An effective Internal Control System (ICS) is essential to ensure compliance with the Annual Procurement of Goods and Services of the State, because both integrated systems allow correct decisions in the long term, medium term and short-term oriented every day. In the present study used the descriptive method transactional. The study population consisted of 27 workers who participated in the process of contracting for goods and services in 2010. The results of this study establish that an average of 73.16% is not applied the SCI the processes of procurement of goods and services of the State Logistics Unit of the Hospital La Caleta de Chimbote, among the main causes of this gap are not socialized the SCI and the processes of contracting, the dominant paradigm is expressed in that management control should be in the hands of professionals only, not prioritized risks, infringe the regulations on the subject, not invested in training of human talent , weak actions of Institutional Control Authority, corruption or misconduct, lack of internal controls in the Logistics Unit for monitoring and evaluating the management of procurement processes for goods and services. These situations also threaten the resource management of the entity level, effectiveness and efficiency of operations, reliability of financial reporting and compliance with laws, regulations and policies. Faced with this problem we propose a comprehensive internal control system, consistently and effectively apply to procurement of goods and services produced in compliance with the guidelines and legal regulations on the subject, the same should be implemented gradually, after training and socialization of human potential. In the design of the proposal followed four phases known as: planning, implementation, evaluation and reporting. The process of implementing the proposed internal control system will materialize to the extent that it has the full commitment and support from the highest levels of government and the efforts of employees of the entity, specifically of officials and servants of the body responsible for the procurement of the Bank, on account of their functions directly involved in any stage of recruitment

Bioactive compounds, minerals and antioxidants of edible flowers of peach and apple

ABSTRACTPeach and apple flowers were evaluated for their human nutritional value by obtaining baseline information on their contents of bioactive compounds, minerals and antioxidant capacity. We used simple random sampling and nested statistical analysis to examine flowers of three peach cultivars (“July Flame,” “Cary Mac” and “Fair Time”) and two crab apple cultivars (“Manchurian” and “John Downie”). Flowers of “John Downie” stood out for their high contents of ash, protein and crude fat. Carbohydrate contents were highest for “Fair Time” and “Cary Mac.” Peach and apple differed in their contents of total phenols (73.23 ± 1.94 mg GAE/g peach and 86.65 ± 1.18 mg GAE/g, apple) and total flavonoids (TFl) (5.29 ± 0.10 mg QE/100 g peach and 7.99 ± 0.3 mg QE/100 g apple). The peach cultivar “Fair Time” and the crab apple cultivars “Manchurian” and “John Downie” showed the highest values of K+ and Mg2+. Micronutrient concentrations differed between species, however, Zn2+ and Na+ values were similar among species but differed between cultivars. Antioxidant capacity showed inter-species variations with the methods ABTS and FRAP. The results indicate a good potential for both peach and apple flowers to be incorporated in the human diet, for fresh consumption as functional foods

The Role of Propolis as a Natural Product with Potential Gastric Cancer Treatment Properties: A Systematic Review

Gastric cancer is one of the most common, aggressive, and invasive types of malignant neoplasia. It ranks fifth for incidence and fourth for prevalence worldwide. Products of natural origin, such as propolis, have been assessed for use as new complementary therapies to combat cancer. Propolis is a bee product with antiproliferative and anticancer properties. The concentrations and types of secondary metabolites contained in propolis mainly vary according to the geographical region, the season of the year, and the species of bees that make it. The present study is a systematic review of the main articles related to the effects of propolis against gastric cancer published between 2011 and 2021 in the PubMed and Science Direct databases. Of 1305 articles published, only eight studies were selected; among their principal characteristics was the use of in vitro analysis with cell lines from gastric adenocarcinoma and in vivo murine models of the application of propolis treatments. These studies suggest that propolis arrests the cell cycle and inhibits proliferation, prevents the release of oxidizing agents, and promotes apoptosis. In vivo assays showed that propolis decreased the number of tumors by regulating the cell cycle and the expression of proteins related to apoptosis

Flavonoids Present in Propolis in the Battle against Photoaging and Psoriasis

The skin is the main external organ. It protects against different types of potentially harmful agents, such as pathogens, or physical factors, such as radiation. Skin disorders are very diverse, and some of them lack adequate and accessible treatment. The photoaging of the skin is a problem of great relevance since it is related to the development of cancer, while psoriasis is a chronic inflammatory disease that causes scaly skin lesions and deterioration of the lifestyle of people affected. These diseases affect the patient’s health and quality of life, so alternatives have been sought that improve the treatment for these diseases. This review focuses on describing the properties and benefits of flavonoids from propolis against these diseases. The information collected shows that the antioxidant and anti-inflammatory properties of flavonoids play a crucial role in the control and regulation of the cellular and biochemical alterations caused by these diseases; moreover, flavones, flavonols, flavanones, flavan-3-ols, and isoflavones contained in different worldwide propolis samples are the types of flavonoids usually evaluated in both diseases. Therefore, the research carried out in the area of dermatology with bioactive compounds of different origins is of great relevance to developing preventive and therapeutic approaches

Antifungal Activity of Mexican Propolis on Clinical Isolates of <i>Candida</i> Species

Infections caused by micro-organisms of the genus Candida are becoming a growing health problem worldwide. These fungi are opportunistic commensals that can produce infections—clinically known as candidiasis—in immunocompromised individuals. The indiscriminate use of different anti-fungal treatments has triggered the resistance of Candida species to currently used therapies. In this sense, propolis has been shown to have potent antimicrobial properties and thus can be used as an approach for the inhibition of Candida species. Therefore, this work aims to evaluate the anti-Candida effects of a propolis extract obtained from the north of Mexico on clinical isolates of Candida species. Candida species were specifically identified from oral lesions, and both the qualitative and quantitative anti-Candida effects of the Mexican propolis were evaluated, as well as its inhibitory effect on C. albicans isolate’s germ tube growth and chemical composition. Three Candida species were identified, and our results indicated that the inhibition halos of the propolis ranged from 7.6 to 21.43 mm, while that of the MFC and FC50 ranged from 0.312 to 1.25 and 0.014 to 0.244 mg/mL, respectively. Moreover, the propolis was found to inhibit germ tube formation (IC50 ranging from 0.030 to 1.291 mg/mL). Chemical composition analysis indicated the presence of flavonoids, including pinocembrin, baicalein, pinobanksin chalcone, rhamnetin, and biochanin A, in the Mexican propolis extract. In summary, our work shows that Mexican propolis presents significant anti-Candida effects related to its chemical composition, and also inhibits germ tube growth. Other Candida species virulence factors should be investigated in future research in order to determine the mechanisms associated with antifungal effects against them