Diagnostic value of fine-needle aspiration biopsy for breast mass: a systematic review and meta-analysis

<p>Abstract</p> <p>Background</p> <p>Fine-needle aspiration biopsy (FNAB) of the breast is a minimally invasive yet maximally diagnostic method. However, the clinical use of FNAB has been questioned. The purpose of our study was to establish the overall value of FNAC in the diagnosis of breast lesions.</p> <p>Methods</p> <p>After a review and quality assessment of 46 studies, sensitivity, specificity and other measures of accuracy of FNAB for evaluating breast lesions were pooled using random-effects models. Summary receiver operating characteristic curves were used to summarize overall accuracy. The sensitivity and specificity for the studies data (included unsatisfactory samples) and underestimation rate of unsatisfactory samples were also calculated.</p> <p>Results</p> <p>The summary estimates for FNAB in diagnosis of breast carcinoma were as follows (unsatisfactory samples was temporarily exluded): sensitivity, 0.927 (95% confidence interval [CI], 0.921 to 0.933); specificity, 0.948 (95% CI, 0.943 to 0.952); positive likelihood ratio, 25.72 (95% CI, 17.35 to 28.13); negative likelihood ratio, 0.08 (95% CI, 0.06 to 0.11); diagnostic odds ratio, 429.73 (95% CI, 241.75 to 763.87); The pooled sensitivity and specificity for 11 studies, which reported unsatisfactory samples (unsatisfactory samples was considered to be positive in this classification) were 0.920 (95% CI, 0.906 to 0.933) and 0.768 (95% CI, 0.751 to 0.784) respectively. The pooled proportion of unsatisfactory samples that were subsequently upgraded to various grade cancers was 27.5% (95% CI, 0.221 to 0.296).</p> <p>Conclusions</p> <p>FNAB is an accurate biopsy for evaluating breast malignancy if rigorous criteria are used. With regard to unsatisfactory samples, futher invasive procedures are required in order to minimize the chance of a missed diagnosis of breast cancer.</p

Notas taxonômicas sobre os Brachiacanthini neotropicais (Coleoptera, Coccinellidae, Hyperaspinae) Taxonomical notes on neotropical Brachiacanthini (Coleoptera, Coccinellidae, Hyperaspinae)

Brachiacantha Chevrolat in Dejean, 1837, Hinda Mulsant, 1850, Cyra Mulsant, 1850 e Tiphysa Mulsant, 1850 foram estudados e é fornecida uma chave para os gêneros. Cleothera loricata Mulsant, 1850 é designada espécie-tipo de Cyra. O lectótipo de Brachiacantha sellata é designado. Três novas combinações são feitas: Cyra loricata (Mulsant, 1850), Cyra scapulata (Mulsant, 1853) e Cyra turbata (Mulsant, 1850). Estão incluídas diagnoses e ilustrações dos caracteres.<br>Brachiacantha Chevrolat in Dejean, 1837, Hinda Mulsant, 1850, Cyra Mulsant, 1850 and Tiphysa Mulsant, 1850 were studied, and a key to genera is added. Cleothera loricata Mulsant, 1850 is designated type species of Cyra. The lectotype of Brachiacantha sellata is designated. Three new combinations are proposed: Cyra loricata (Mulsant, 1850), Cyra scapulata (Mulsant, 1853) and Cyra turbata (Mulsant, 1850). Diagnosis and illustrations of characters are provided

Coleoptera Collected from Rotting Fishhook Barrel Cacti (Ferocactus wislizeni (Engelm.) Britton and Rose), with a Review of Nearctic Coleoptera Associated with Succulent Necrosis

Fig. 5. Principal coordinates analysis based on moisture content. Dry is distinctly grouped, while Moist and Wet have minimal overlap.Published as part of &lt;i&gt;Ferro, Michael L., Nguyen, Nhu H., Tishechkin, Alexey, Park, Jong-Seok, Bayless, Victoria &amp; Carlton, Christopher E., 2013, Coleoptera Collected from Rotting Fishhook Barrel Cacti (Ferocactus wislizeni (Engelm.) Britton and Rose), with a Review of Nearctic Coleoptera Associated with Succulent Necrosis, pp. 419-443 in The Coleopterists Bulletin 67 (4)&lt;/i&gt; on page 425, DOI: 10.1649/0010-065x-67.4.419, &lt;a href="http://zenodo.org/record/10103939"&gt;http://zenodo.org/record/10103939&lt;/a&gt