163 research outputs found
Building a culture of participation: involving children and young people in policy,service planning, delivery and evaluation: handbook
60 Years of the Universal Declaration of Human Rights: Towards an Individual Responsibility to Protect
The Impact of Summer Camp on Social Skills for Children with Autism Spectrum Disorder
This study examined specific social skills that children with Autism Spectrum Disorder need to improve in their life. This quantitative study obtained data from 40 parents who have children or youth with ASD who participated in a one week day camp. A modified version of the Autism Social Skills Profile (ASSP) was given three times to determine if children and youth with ASD made improvements in social skills after participating in the one week day camp. Survey 1 was distributed before the beginning of camp, survey 2 was given at the end of camp, and survey 3 was given eight weeks post camp. This study reported statistically significant differences when the five domains included in social skills (communication, reciprocity, social cognition, initiation, and perspective taking and self-awareness) were analyzed. The time by treatment interaction was statistically significant for the communication, initiation, and reciprocity domains. These results suggest that participants who attended Camp New Amigos showed a positive impact on social skills for children and youth with ASD, as rated by their parents. Keywords: communication, social skills, imitation, social cognition, perspective taking DOI: 10.7176/JEP/11-17-14 Publication date:June 30th 202
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HIV transmission networks among transgender women in Los Angeles County, CA, USA: a phylogenetic analysis of surveillance data.
BackgroundTransgender women are among the groups at highest risk for HIV infection, with a prevalence of 27·7% in the USA; and despite this known high risk, undiagnosed infection is common in this population. We set out to identify transgender women and their partners in a molecular transmission network to prioritise public health activities.MethodsSince 2006, HIV protease and reverse transcriptase gene (pol) sequences from drug resistance testing have been reported to the Los Angeles County Department of Public Health and linked to demographic data, gender, and HIV transmission risk factor data for each case in the enhanced HIV/AIDS Reporting System. We reconstructed a molecular transmission network by use of HIV-TRAnsmission Cluster Engine (with a pairwise genetic distance threshold of 0·015 substitutions per site) from the earliest pol sequences from 22 398 unique individuals, including 412 (2%) self-identified transgender women. We examined the possible predictors of clustering with multivariate logistic regression. We characterised the genetically linked partners of transgender women and calculated assortativity (the tendency for people to link to other people with the same attributes) for each transmission risk group.Findings8133 (36·3%) of 22 398 individuals clustered in the network across 1722 molecular transmission clusters. Transgender women who indicated a sexual risk factor clustered at the highest frequency in the network, with 147 (43%) of 345 being linked to at least one other person (adjusted odds ratio [aOR] 2·0, p=0·0002). Transgender women were assortative in the network (assortativity 0·06, p<0·001), indicating that they tended to link to other transgender women. Transgender women were more likely than expected to link to other transgender women (OR 4·65, p<0·001) and cisgender men who did not identify as men who have sex with men (MSM; OR 1·53, p<0·001). Transgender women were less likely than expected to link to MSM (OR 0·75, p<0·001), despite the high prevalence of HIV among MSM. Transgender women were distributed across 126 clusters, and cisgender individuals linked to one transgender woman were 9·2 times more likely to link to a second transgender woman than other individuals in the surveillance database. Reconstruction of the transmission network is limited by sample availability, but sequences were available for more than 40% of diagnoses.InterpretationClustering of transgender women and the observed tendency for linkage with cisgender men who did not identify as MSM, shows the potential to use molecular epidemiology both to identify clusters that are likely to include undiagnosed transgender women with HIV and to improve the targeting of public health prevention and treatment services to transgender women.FundingCalifornia HIV and AIDS Research Program and National Institutes of Health-National Institute of Allergy and Infectious Diseases
The cost of caring: Dave’s story
Dave’s story is an important narrative that explores how caring for athletes may reflexively influence the personal and social lives of coaches. The narrative begins by revealing some of the ways that coaches may care for athletes and their wider well-being. For example, Dave uses basketball as a vehicle to support athletes’ education. He also provides pastoral care to athletes with challenging family and social circumstances. This ‘labour’ can, however, be time consuming and emotionally intensive. Accordingly, caring for athletes can have significant negative consequences for coaches’ own personal and social lives. Readers may recognise Dave’s struggles to balance caring for athletes and a passion for sport with his family commitments. To aid readers in such positions, Dave’s story is analysed with reference to sociological literature on emotional labour and psychological literature on burnout. The combination of these literatures is novel and provides theoretical explanations relevant to the wider coaching community. Practical suggestions for coaches who may find caring to be an exhausting form of labour are also included, as are future implications for coach researchers and educators. Thus, the chapter provides an important case study that can impact coach development and coaching practice
Challenges of Measuring Abyssal Temperature and Salinity at the Kuroshio Extension Observatory
The deep ocean is severely undersampled. Whereas shipboard measurements provide irregular spatial and temporal records, moored records establish deep ocean high-resolution time series, but only at limited locations. Here, highlights and challenges of measuring abyssal temperature and salinity on the Kuroshio Extension Observatory (KEO) mooring (32.3°N, 144.6°E) from 2013 to 2019 are described. Using alternating SeaBird 37-SMP instruments on annual deployments, an apparent fresh drift of 0.03–0.06 psu was observed, with each newly deployed sensor returning to historical norms near 34.685 psu. Recurrent salinity discontinuities were pronounced between the termination of each deployment and the initiation of the next, yet consistent pre- and postdeployment calibrations suggested the freshening was “real.” Because abyssal salinities do not vary by 0.03–0.06 psu between deployment locations, the contradictory salinities during mooring overlap pointed toward a sensor issue that self-corrects prior to postcalibration. A persistent nepheloid layer, unique to KEO and characterized by murky, sediment-filled water, is likely responsible for sediment accretion in the conductivity cell. As sediment (or biofouling) increasingly clogs the instrument, salinity drifts toward a fresh bias. During ascent, the cell is flushed, clearing the clogged instrument. In contrast to salinity, deep ocean temperatures appear to increase from 2013 to 2017 by 0.0059°C, whereas a comparison with historical deep temperature measurements does not support a secular temperature increase in the region. It is suggested that decadal or interannual variability associated with the Kuroshio Extension may have an imprint on deep temperatures. Recommendations are discussed for future abyssal temperature and salinity measurements
Comparison of SEER Treatment Data With Medicare Claims
The population-based Surveillance, Epidemiology, and End Results (SEER) registries collect information on first-course treatment, including surgery, chemotherapy, radiation therapy, and hormone therapy. However, the SEER program does not release data on chemotherapy or hormone therapy due to uncertainties regarding data completeness. Activities are ongoing to investigate the opportunity to supplement SEER treatment data with other data sources
Timing of therapy for latent tuberculosis infection among immigrants presenting to a U.S. public health clinic: a retrospective study
<p>Abstract</p> <p>Background</p> <p>In the U.S. more than half of incident tuberculosis (TB) cases occur in immigrants. Current guidelines recommend screening and treatment for latent TB infection (LTBI) within 5 years of arrival to the U.S. This study evaluates the timing of LTBI therapy among immigrants presenting for care to a public health TB clinic.</p> <p>Methods</p> <p>Retrospective chart review of patients prescribed LTBI treatment based on medical records from Prince Georges County Health Department.</p> <p>Results</p> <p>1882 immigrants received LTBI therapy at Prince Georges County Health Department between 1999 and 2004. 417 of these patients were diagnosed with LTBI through contact investigations and were excluded from the analysis. Among the remaining 1465 individuals, median time from arrival to the U.S. until initiation of LTBI therapy was 5 months (range 0–42.4 years). 16% of all immigrants initiated therapy more than 5 years after arrival to the U.S. A logistic regression model using risks identified on univariate analysis revealed that referral for therapy by non-immigration proceedings was the strongest predictor of initiation of therapy more than 5 years after arrival to the U.S. Other factors associated with > 5 year U.S. residence prior to initiation of LTBI therapy included female gender (adjusted odds ratio (AOR) 1.8, 95% CI 1.2–2.6), age ≥ 35 (AOR = 4.1, 95% 2.5–6.6), and originating from Latin American and the Caribbean (AOR = 1.9, 95% CI 1.3–3.0).</p> <p>Conclusion</p> <p>Foreign-born individuals who are not referred for LTBI therapy through immigration proceedings are less likely to receive LTBI therapy within 5 years of arrival to the U.S. These data highlight the need to explore other mechanisms for timely LTBI screening beyond services provided by immigration.</p
Cognitive Effects of Risperidone in Children with Autism and Irritable Behavior
Objective:
The objective of this research was to explore the effects of risperidone on cognitive processes in
children with autism and irritable behavior.
Method:
Thirty-eight children, ages 5-17 years with autism and severe behavioral disturbance, were
randomly assigned to risperidone (0.5 to 3.5 mg/day) or placebo for 8 weeks. This sample of 38 was a subset
of 101 subjects who participated in the clinical trial; 63 were unable to perform the cognitive tasks. A
double-blind placebo-controlled parallel groups design was used. Dependent measures included tests of
sustained attention, verbal learning, hand-eye coordination, and spatial memory assessed before, during, and
after the 8-week treatment. Changes in performance were compared by repeated measures ANOVA.
Results:
Twenty-nine boys and 9 girls with autism and severe behavioral disturbance and a mental age ≥18
months completed the cognitive part of the study. No decline in performance occurred with risperidone.
Performance on a cancellation task (number of correct detections) and a verbal learning task (word
recognition) was better on risperidone than on placebo (without correction for multiplicity). Equivocal
improvement also occurred on a spatial memory task. There were no significant differences between
treatment conditions on the Purdue Pegboard (hand-eye coordination) task or the Analog Classroom Task
(timed math test).
Conclusion:
Risperidone given to children with autism at doses up to 3.5 mg for up to 8 weeks appears to have no
detrimental effect on cognitive performance
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