IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22–23

19openopenAli G. Gharavi; Yan Yan; Francesco Scolari; F. Paolo Schena; Giovanni M. Frasca; Gian Marco Ghiggeri; Kerry Cooper; Antonio Amoroso; Battista Fabio Viola; Graziana Battini10; Gianluca Caridi8; Cristina Canova; Anita Farhi; Vairavan Subramanian; Carol Nelson-Williams; Sue Woodford; Bruce A. Julian; Robert J. Wyatt; Richard P. LiftonAli G., Gharavi; Yan, Yan; Scolari, Francesco; F., Paolo Schena; Giovanni M., Frasca; Gian Marco, Ghiggeri; Kerry, Cooper; Antonio, Amoroso; Battista Fabio, Viola; Graziana, Battini10; Gianluca, Caridi8; Cristina, Canova; Anita, Farhi; Vairavan, Subramanian; Carol Nelson, Williams; Sue, Woodford; Bruce A., Julian; Robert J., Wyatt; Richard P., Lifto

Studiul biochimic la genotipurile de Hyssopus officinalis l. din Republica Moldova

Centrul Științifico-Practic în domeniul Plantelor Medicinale, USMF „Nicolae Testemiţanu”Background. H. officinalis L. - medicinal, culinary plant widespread in Europe and Asia. The main phenolic compounds are flavonoids and hydroxycinnamic acids, with carminative, tonic, antiseptic, expectorant and antitussive properties. Objective of the study. Chemical study of plant products and dry extracts obtained from aerial parts of H. officinalis genotypes from the collection of SPCFMP. Material and Methods. The aerial parts of 3 genotypes of H. officinalis (cyaneus, ruber, albus) were collected. The dried extracts were obtained by fractional maceration with shaking. Phenolic compounds were identified by thin layer chromatography. The total phenolic acids with Arnow reagent and the total polyphenols with Folin-Ciocalteu reagent were determined spectrophotometrically. Results. Were identified rutozide (Rf = 0,93), caffeic (Rf = 0,21) and chlorogenic (Rf = 0,47) acids in dried extracts obtained from Hyssopi herba with white, pink and blue flowers. The maximum concentration of hydroxycinnamic acids was in the plant product and dry extract of H. officinalis (albus) - 1.48 and 3.01 mg/g, followed by H. officinalis (ruber) - 1.19 and 2.92 mg/g and H. officinalis (cyaneus) - 1.015 and 2.85 mg/g. The total polyphenols were higher in the dried extract of Hyssopi herba with blue flowers (39,06 mg/g), followed by the dried extracts of Hyssopi herba with white flowers (36,11 mg/g) and Hyssopi herba with pink flowers (33,08 mg/g). Conclusion. H. officinalis (cyaneus, ruber and albus) grown in the Republic of Moldova are important sources of active substances of medicinal interest, but require several biochemical studies to confirm their therapeutic potential. Research was carried out within the framework of the State Programme Project number 20.80009.8007.24.Introducere. H. officinalis L. – plantă medicinală, culinară răspândită în Europa și Asia. Principalii compuși fenolici sunt flavonoidele și acizii hidroxicinamici, cu proprietăți carminative, tonice, antiseptice, expectorante și antitusive. Scopul lucrării. Studiul chimic al produselor vegetale și extractelor uscate obținute din părțile aeriene la genotipuri de H. officinalis din colecția CȘPDPM. Materiale şi metode. S-au colectat părțile aeriene la 3 genotipuri de H. officinalis (cyaneus, ruber, albus). Extractele uscate s-au obținut prin macerarea fracționată cu agitare. Compușii fenolici s-au identificat prin cromatografie pe strat subțire. Conținutul total de acizi fenolici cu reactivul Arnow și totalul de polifenoli cu reactivul Folin-Ciocalteu s-a determinat spectrofototometric. Rezultate. În extractele uscate din Hyssopi herba cu flori albe, roz și albastre s-a identificat rutozida (Rf = 0,93), acizii cafeic (Rf = 0,21) și clorogenic (Rf = 0,47). Concentrația maximă de acizi hidroxicinamici a fost în produsul vegetal și extractul uscat de H. officinalis (albus) – 1,48 și 3,01 mg/g, urmat de H. officinalis (ruber) - 1,19 și 2,92 mg/g și de H. officinalis L. (cyaneus) – 1,015 și 2,85 mg/g. Totalul de polifenoli s-a dovedit mai înalt în extactul uscat din Hyssopi herba cu flori albastre (39,06 mg/g), urmat de extactele uscate din Hyssopi herba cu flori albe (36,11 mg/g) și Hyssopi herba cu flori roz (33,08 mg/g). Concluzii. H. officinalis L. (cyaneus, ruber şi albus) cultivate în R. Moldova sunt surse importante de substanțe active de interes medicinal, dar necesită mai multe studii biochimice pentru a confirma potențialul lor terapeutic. Cercetările s-au realizat în cadrul proiectului din Programul de Stat 20.80009.8007.24

Emissão de metano em sistemas de produção de bovinos de corte brasileiro.

Editores técnicos: João de Mendonça Naime, Caue Ribeiro, Maria Alice Martins, Elaine Cristina Paris, Paulino Ribeiro Villas Boas, Ladislau Marcelino Rabello

Efeito da desfolha e da irrigação nos componentes da produção de sementes de cornichão (Lotus corniculatus L.).

O objetivo do trabalho foi avaliar o efeito do corte pré-florescimento e da irrigação pré-colheita na produção de sementes de cornichão.Claudia Cristina Gulias Gomes, editora técnica

Biosorption of diethylketone and Cd using a Streptococcus equisimilis biofilm supported on vermiculite: kinetics and equilibrium studies

WMESS 2015 - The World Multidisciplinary Earth Sciences SymposiumThis works aims to infer about the possible application of a supported biofilm on the simultaneous removal of a metal and a ketone from aqueous solutions and accordingly it describes two sets of experiments: cadmium and diethylketone, DEK, adsorption assays on vermiculite, the support, and cadmium and diethylketone biosorption assays on vermiculite covered by a S. equisimilis biofilm. Removal percentages between 60 % and 98 % were obtained by the vermiculite for initials concentrations of 3g/L of DEK. For Cd, the removal percentage ranged between 72 % and 78% for initials concentrations of 0.1 g/L of metal. Regarding the assays conducted with the S. equisimilis biofilm supported on vermiculite, the percentage of removed cadmium increases with the increase of the amount of vermiculite whereas DEK removal decreases (maximum removals of 86.16 % and 95.70 % for Cd and DEK, respectively). Adsorption kinetics for both pollutants follows the pseudo-second order model and equilibria are well described by the Freundlich and by the Dubinin-Radushkevich models for Cd and DEK respectively.info:eu-repo/semantics/publishedVersio

Moesziomyces spp. cultivation using cheese whey: new yeast extract-free media, beta-galactosidase biosynthesis and mannosylerythritol lipids production

ABSTRACT: Mannosylerythritol lipids (MELs) are biosurfactants with excellent biochemical properties and a wide range of potential applications. However, high production costs, low productivity and unsatisfactory scale-up production have hampered commercial adoption. Herein, we report for the first time the beta-galactosidase production by Moesziomyces spp. from different sugars (D-galactose, D-glucose and D-lactose), with D-galactose being the best beta-galactosidase inducer, with 11.2 and 63.1 IU/mg(biomass), for Moesziomyces aphidis 5535(T) and Moesziomyces antarcticus 5048(T), respectively. The production of this enzyme allows to break down D-lactose and thus to produce MEL directly from D-lactose or cheese whey (a cheese industry by-product). Remarkably, when CW was used as sole media component (carbon and mineral source), in combination with waste frying oil, MEL productivities were very close (1.40 and 1.31 g(MEL)/L/day) to the ones obtained with optimized medium containing yeast extract (1.92 and 1.50 g(MEL)/g(susbtrate)), both for M. antarcticus and M. aphidis. The low-cost, facile and efficient process which generates large amounts of MELs potentiates its industrialization.info:eu-repo/semantics/publishedVersio

Exploring non-edible parts of pineapples as fat replacers in cake formulations

Non-edible parts of many fruits, such as peel and seeds, are sources of compounds with important nutritional properties. They are also rich in fibres, which gives them the potential to be used as functional ingredients since fibres may be fat replacers in many food formulations. If these parts of fruits are properly transformed into edible forms, there will be potential reuse and recovery of food waste. In the case of pineapple, approximately 70% of the total weight of the fruit is not consumed, being rinds, core, and crown usually discarded. This work aimed to transform pineapples' non-edible parts (rinds and crowns) into powders by freeze-drying with posterior micronization. The objective was to use the powders as fat replacers in a traditional cupcake recipe and assess the texture profile of the baked cakes. Pineapples (Ananas comosus L.) rinds and crowns were removed, cut into small pieces, and freeze-dried. The dried samples were ground in a hammer mill to obtain powders/flours. They were characterized in terms of water activity, water and oil absorption capacity (WAC and OAC), proteins, and total dietary fibre content (on a dry basis, d.b.). These powders were used in a cupcake recipe (control), replacing the fat (butter) with the powders in different proportions: 25, 50, and 75%. Relevant textural parameters such as hardness, cohesiveness, chewiness, and springiness were assessed in the baked cupcakes. Water activity values of rind and crown powders were 0.36±0.02 and 0.49±0.03, respectively. Regarding functional properties, crown flours presented a considerably higher OAC (6.11±0.39 g oil/g d.b.) than the rind (2.45±0.47 g oil/g d.b.); WAC of both flours was similar, averaging 2.30±0.34 g water/g d.b. Protein content was significantly higher in the crown (8.14±0.89 g/100 g d.b.) than in the rind flours (4.43±0.38 g/100 g d.b.). Dietary fibres were mainly insoluble; the crown had 18% and the skin 37%.The texture of cupcakes with 25% of both types of flour was similar to the control. However, as the proportions of the flours increased, texture differed mainly in crown-based recipes, becoming the cakes harder with springiness and adhesiveness decay. These findings suggest that incorporating pineapple waste parts in a traditional cake recipe may serve as healthier ingredients with improved functional properties.info:eu-repo/semantics/publishedVersio