409 research outputs found
Solar Oscillations and Convection: II. Excitation of Radial Oscillations
Solar p-mode oscillations are excited by the work of stochastic,
non-adiabatic, pressure fluctuations on the compressive modes. We evaluate the
expression for the radial mode excitation rate derived by Nordlund and Stein
(Paper I) using numerical simulations of near surface solar convection. We
first apply this expression to the three radial modes of the simulation and
obtain good agreement between the predicted excitation rate and the actual mode
damping rates as determined from their energies and the widths of their
resolved spectral profiles. We then apply this expression for the mode
excitation rate to the solar modes and obtain excellent agreement with the low
l damping rates determined from GOLF data. Excitation occurs close to the
surface, mainly in the intergranular lanes and near the boundaries of granules
(where turbulence and radiative cooling are large). The non-adiabatic pressure
fluctuations near the surface are produced by small instantaneous local
imbalances between the divergence of the radiative and convective fluxes near
the solar surface. Below the surface, the non-adiabatic pressure fluctuations
are produced primarily by turbulent pressure fluctuations (Reynolds stresses).
The frequency dependence of the mode excitation is due to effects of the mode
structure and the pressure fluctuation spectrum. Excitation is small at low
frequencies due to mode properties -- the mode compression decreases and the
mode mass increases at low frequency. Excitation is small at high frequencies
due to the pressure fluctuation spectrum -- pressure fluctuations become small
at high frequencies because they are due to convection which is a long time
scale phenomena compared to the dominant p-mode periods.Comment: Accepted for publication in ApJ (scheduled for Dec 10, 2000 issue).
17 pages, 27 figures, some with reduced resolution -- high resolution
versions available at http://www.astro.ku.dk/~aake/astro-ph/0008048
A Search for Propylene Oxide and Glycine in Sagittarius B2 (LMH) and Orion
We have used the Mopra Telescope to search for glycine and the simple chiral
molecule propylene oxide in the Sgr B2 (LMH) and Orion KL, in the 3-mm band. We
have not detected either species, but have been able to put sensitive upper
limits on the abundances of both molecules. The 3-sigma upper limits derived
for glycine conformer I are 3.7 x 10^{14} cm^{-2} in both Orion-KL and Sgr B2
(LMH), comparable to the reported detections of conformer I by Kuan et al.
However, as our values are 3-sigma upper limits rather than detections we
conclude that this weighs against confirming the detection of Kuan et al. We
find upper limits for the glycine II column density of 7.7 x 10^{12} cm^{-2} in
both Orion-KL and Sgr B2 (LMH), in agreement with the results of Combes et al.
The results presented here show that glycine conformer II is not present in the
extended gas at the levels detected by Kuan et al. for conformer I. Our ATCA
results (Jones et al.) have ruled out the detection of glycine (both conformers
I and II) in the compact hot core of the LMH at the levels reported, so we
conclude that it is unlikely that Kuan et al. have detected glycine in either
Sgr B2 or Orion-KL. We find upper limits for propylene oxide abundance of 3.0 x
10^{14} cm^{-2} in Orion-KL and 6.7 x 10^{14} cm^{-2} in Sgr B2 (LMH). We have
detected fourteen features in Sgr B2 and four features in Orion-KL which have
not previously been reported in the ISM, but have not be able to plausibly
assign these transitions to any carrier.Comment: 12 pages, 3 figures. Accepted by MNRAS 12th January 200
TSC22 in mammary gland development and breast cancer
Mammary gland involution is characterised by a high degree of apoptosis. By identifying genes that are upregulated at this developmental stage, we aimed to discover key factors that are involved in the induction of mammary epithelial cell death and therefore present potential tumour suppressors for breast cancer. Among 96 genes recently identified as specifically upregulated early during involution were the transforming growth factor beta (TGFβ)-stimulated clone 22 homologue (TSC-22/TGFβ1-induced transcript 4) and TGFβ3 [1]. TGFβ3 has recently been shown to be necessary for induction of apoptosis during mammary gland involution, while TSC-22 overexpression can lead to cell death. We have therefore tested whether TSC-22 mRNA expression can be induced by TGFβ3 and whether it is involved in or necessary for TGFβ-induced apoptosis. We further show that TSC-22 can enhance TGFβ3-induced Smad response and epithelial cell death. In addition, overexpression of TSC-22 alone can induce a Smad response and apoptosis in mammary epithelial cell cultures, which is independent of p53. Further, we have performed tests to study the necessity for Smad proteins during TSC-22-induced apoptosis, and to establish the intracellular localisation of TSC-22. A pilot study on a small cohort of archival breast cancer cases, representing all stages of malignant progression, shows that TSC-22 protein was reduced or undetectable in 60% of breast carcinomas when compared with adjacent normal breast tissue, suggesting that TSC-22 could indeed be a potential novel tumour suppressor gene. We shall present data showing that methylation of the TSC-22 promoter is not involved in the reduction of TSC-22 protein in breast cancer
Current practices in weight making sport
All combat and a number of non-combat sports follow differing degrees of weight categorisation (see Table 1) and there are also a number of aesthetically judged sports where it is considered advantageous to have the lowest fat mass possible, including gymnastics, body building, bikini modelling, etc. The rationale for weight categorisation is to promote fairer competition between competitors of equal size/body mass and stature/height (Langan-Evans et al., 2011). However, many weight categorised athletes lose large amounts of body mass to gain a competitive advantage in either height, limb length or power to mass ratio. Several studies have shown these athletes employ short duration or ‘rapid weight loss’ (RWL) techniques, whereas others maintain low energy availability over prolonged periods of time. As such, a recent article has called for RWL to be banned (Artioli et al., 2016) and others have highlighted the dangers of consistently reduced energy availability (Mountjoy et al., 2014). This article highlights some of the body mass loss practices employed by athletes across a range of sports and demonstrate the impact that this has on psychophysiological health
Gas Accretion via Lyman Limit Systems
In cosmological simulations, a large fraction of the partial Lyman limit
systems (pLLSs; 16<log N(HI)<17.2) and LLSs (17.2log N(HI)<19) probes
large-scale flows in and out of galaxies through their circumgalactic medium
(CGM). The overall low metallicity of the cold gaseous streams feeding galaxies
seen in these simulations is the key to differentiating them from metal rich
gas that is either outflowing or being recycled. In recent years, several
groups have empirically determined an entirely new wealth of information on the
pLLSs and LLSs over a wide range of redshifts. A major focus of the recent
research has been to empirically determine the metallicity distribution of the
gas probed by pLLSs and LLSs in sizable and representative samples at both low
(z2) redshifts. Here I discuss unambiguous evidence for
metal-poor gas at all z probed by the pLLSs and LLSs. At z<1, all the pLLSs and
LLSs so far studied are located in the CGM of galaxies with projected distances
<100-200 kpc. Regardless of the exact origin of the low-metallicity pLLSs/LLSs,
there is a significant mass of cool, dense, low-metallicity gas in the CGM that
may be available as fuel for continuing star formation in galaxies over cosmic
time. As such, the metal-poor pLLSs and LLSs are currently among the best
observational evidence of cold, metal-poor gas accretion onto galaxies.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springe
Gas Accretion in Star-Forming Galaxies
Cold-mode gas accretion onto galaxies is a direct prediction of LCDM
simulations and provides galaxies with fuel that allows them to continue to
form stars over the lifetime of the Universe. Given its dramatic influence on a
galaxy's gas reservoir, gas accretion has to be largely responsible for how
galaxies form and evolve. Therefore, given the importance of gas accretion, it
is necessary to observe and quantify how these gas flows affect galaxy
evolution. However, observational data have yet to conclusively show that gas
accretion ubiquitously occurs at any epoch. Directly detecting gas accretion is
a challenging endeavor and we now have obtained a significant amount of
observational evidence to support it. This chapter reviews the current
observational evidence of gas accretion onto star-forming galaxies.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springer. This chapter includes 22 pages with 7 Figure
Dissipation of vibration in rough contact
The relationship which links the normal vibration occurring during the sliding of rough surfaces and the nominal contact area is investigated. Two regimes are found. In the first one, the vibrational level does not depend on the contact area, while in the second one, it is propor- tional to the contact area. A theoretical model is proposed. It is based on the assumption that the vibrational level results from a competition between two processes of vibration damping, the internal damping of the material and the contact damping occurring at the interface
Sentinel monitoring of activity of out-of-hours services in Norway in 2007: an observational study
<p>Abstract</p> <p>Background</p> <p>In Norway, no valid activity statistics from the primary health care out-of-hours services or the pre-hospital emergency health care system have previously been available.</p> <p>Methods</p> <p>The National Centre for Emergency Primary Health Care has initiated an enterprise called "The Watchtowers" which consists of a representative sample of seven casualty clinics covering 18 Norwegian municipalities. The purpose of the project is to provide routine information over several years, which will enable monitoring, evaluation and comparison of the activities in the out-of-hours services. This paper presents data from 2007, the first full calendar year for the Watchtowers, analyzes some differences in user patterns for the seven casualty clinics involved, and estimates national figures for the use of casualty clinics and out-of-hours services in Norway.</p> <p>Results</p> <p>A total of 85 288 contacts were recorded during 2007 [399 per 1 000 inhabitants] of which 64 846 contacts were considered non-urgent [76.6%]. There were 53 467 consultations by a doctor [250 per 1 000], 8 073 telephone consultations by doctor [38 per 1 000], 2 783 home visits and call-outs by doctor [13 per 1000] and 20 502 contacts managed by nurses on their own [96 per 1000]. The most common mode of contact was by telephone. Women, young children and elderly had the highest rates of contact.</p> <p>Conclusion</p> <p>Norway has a high rate of contacts to the out-of-hours services compared with some other countries with available data. Valid national figures and future research of these services are important both for local services and policy makers.</p
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