PARTICIPATION DECISIONS, ANGLER WELFARE, AND THE REGIONAL ECONOMIC IMPACT OF SPORTFISHING

We link a stochastic binary choice model of individual decisions to participate in the marine sport fisheries in Cook Inlet, Alaska, with a simulation- based sample enumeration procedure for aggregating estimates of individual angler welfare and a regionally adjusted zip code-level input-output model of regional economic activity. The result is a behaviorally based model for predicting changes in angler welfare and regional economic activity occasioned by changes in the demand for sportfishing that arise from changes in trip costs or the expected number, size, or mix of species caught. The advantages of this approach are that: changes in angler participation are determined by variables that are observable, predictable, or subject to management control; participation reflects declining marginal utility, and substitution and complementary effects across trip attributes; estimates of changes in aggregate angler welfare and changes in regional economic impacts are derived from changes in individual participation probabilities.Resource /Energy Economics and Policy,

Regional Distribution of Mesospheric Small‐Scale Gravity Waves During DEEPWAVE

The Deep Propagating Gravity Wave Experiment project took place in June and July 2014 in New Zealand. Its overarching goal was to study gravity waves (GWs) as they propagate from the ground up to ~100 km, with a large number of ground‐based, airborne, and satellite instruments, combined with numerical forecast models. A suite of three mesospheric airglow imagers operated onboard the NSF Gulfstream V (GV) aircraft during 25 nighttime flights, recording the GW activity at OH altitude over a large region (\u3e7,000,000 km2). Analysis of this data set reveals the distribution of the small‐scale GW mean power and direction of propagation. GW activity occurred everywhere and during every flight, even over open oceans with no neighboring tropospheric sources. Over the mountainous regions (New Zealand, Tasmania, isolated islands), mean power reached high values (more than 100 times larger than over the waters), but with a considerable variability. This variability existed from day to day over the same region, but even during the same flight, depending on forcing strength and on the middle atmosphere conditions. Results reveal a strong correlation between tropospheric sources, satellite stratospheric measurements, and mesosphere lower thermosphere airglow observations. The large‐amplitude GWs only account for a small amount of the total (~6%), even though they carry the most momentum and energy. The weaker wave activity measured over the oceans might originate from distance sources (polar vortex, weather fronts), implying that a ducted mechanism helped for their long range propagation

An Economic Discussion of the Marine Sport Fisheries in Central and Lower Cook Inlet

This paper reports on the valuation of the marine halibut and salmon sport fishery of central and lower Cook Inlet, Alaska. The project was designed to simulate changes in economic value and regional economic impacts for environmental analysis but has also been used in fishery allocation management. This study develops a predictive model of participation rate changes for estimation of net benefits to anglers and links the resulting demand function to a regional input-output model for determining expenditure-based impacts of marine sportfishing to the Kenai Peninsula economy. The participation rate model is driven by changes in mean sport fishery attributes such as the expected catch rate and weight for various species as well as the average cost of a fishing day. The total estimated new money brought into the Kenai Peninsula as a result of 259,615 saltwater angler days in central and lower Cook Inlet was $37.4 million in 1997, and the total compensating variation,$25.4 million. Simulations involving changes to sportfishing trip attributes from a 1997 baseline trip are examined and reported in the paper.Keywords: sportfishing, halibut, participation-rate, charter, impact analysis, consumer surplus

Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note

Background: Serum procalcitonin levels have been used as a biomarker of invasive bacterial infection and recently have been advocated to guide antibiotic therapy in patients with chronic obstructive pulmonary disease (COPD). However, rigorous studies correlating procalcitonin levels with microbiologic data are lacking. Acute exacerbations of COPD (AECOPD) have been linked to viral and bacterial infection as well as noninfectious causes. Therefore, we evaluated procalcitonin as a predictor of viral versus bacterial infection in patients hospitalized with AECOPD with and without evidence of pneumonia. Methods: Adults hospitalized during the winter with symptoms consistent with AECOPD underwent extensive testing for viral, bacterial, and atypical pathogens. Serum procalcitonin levels were measured on day 1 (admission), day 2, and at one month. Clinical and laboratory features of subjects with viral and bacterial diagnoses were compared.Results: In total, 224 subjects with COPD were admitted for 240 respiratory illnesses. Of these, 56 had pneumonia and 184 had AECOPD alone. A microbiologic diagnosis was made in 76 (56%) of 134 illnesses with reliable bacteriology (26 viral infection, 29 bacterial infection, and 21 mixed viral bacterial infection). Mean procalcitonin levels were significantly higher in patients with pneumonia compared with AECOPD. However, discrimination between viral and bacterial infection using a 0.25 ng/mL threshold for bacterial infection in patients with AECOPD was poor. Conclusion: Procalcitonin is useful in COPD patients for alerting clinicians to invasive bacterial infections such as pneumonia but it does not distinguish bacterial from viral and noninfectious causes of AECOPD

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis

Background Carboxyl-ester lipase (CEL) contributes to fatty acid ethyl ester metabolism, which is implicated in alcoholic pancreatitis. The CEL gene harbours a variable number of tandem repeats (VNTR) region in exon 11. Variation in this VNTR has been linked to monogenic pancreatic disease, while conflicting results were reported for chronic pancreatitis (CP). Here, we aimed to investigate a potential association of CEL VNTR lengths with alcoholic CP. Methods Overall, 395 alcoholic CP patients, 218 patients with alcoholic liver cirrhosis (ALC) serving as controls with a comparable amount of alcohol consumed, and 327 healthy controls from Germany and the United Kingdom (UK) were analysed by determination of fragment lengths by capillary electrophoresis. Allele frequencies and genotypes of different VNTR categories were compared between the groups. Results Twelve repeats were overrepresented in UK ACP patients (P = 0.04) compared to controls, whereas twelve repeats were enriched in German ALC compared to alcoholic CP patients (P = 0.03). Frequencies of CEL VNTR lengths of 14 and 15 repeats differed between German ALC patients and healthy controls (P = 0.03 and 0.008, respectively). However, in the genotype and pooled analysis of VNTR lengths no statistical significant association was depicted. Additionally, the 16–16 genotype as well as 16 repeats were more frequent in UK ALC than in alcoholic CP patients (P = 0.034 and 0.02, respectively). In all other calculations, including pooled German and UK data, allele frequencies and genotype distributions did not differ significantly between patients and controls or between alcoholic CP and ALC. Conclusions We did not obtain evidence that CEL VNTR lengths are associated with alcoholic CP. However, our results suggest that CEL VNTR lengths might associate with ALC, a finding that needs to be clarified in larger cohorts

Variation in treatment of acute childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey of clinician practice

© 2015, BMJ Publishing Group. All rights reserved. Objective: National clinical guidelines for childhood wheeze exist, yet despite being one of the most common reasons for childhood emergency department (ED) attendance, signi ficant variation in practice occurs in other settings. We, therefore, evaluated practice variations of ED clinicians in the UK and Ireland. Design: Two-stage survey undertaken in March 2013. Stage one examined department practice and stage two assessed ED consultant practice in acute childhood wheeze. Questions interrogated pharmacological and other management strategies, including inhaled and intravenous therapies. Setting and participants: Member departments of Paediatric Emergency Research in the United Kingdom and Ireland and ED consultants treating children with acute wheeze. Results: 30 EDs and 183 (81%) clinicians responded. 29 (97%) EDs had wheeze guidelines and 12 (40%) had care pathways. Variation existed between clinicians in dose, timing and frequency of inhaled bronchodilators across severities. When escalating to intravenous bronchodilators, 99 (54%) preferred salbutamol first line, 52 (28%) magnesium sulfate (MgSO4) and 27 (15%) aminophylline. 87 (48%) administered intravenous bronchodilators sequentially and 30 (16%) concurrently, with others basing approach on case severity. 146 (80%) continued inhaled therapy after commencing intravenous bronchodilators. Of 170 who used intravenous salbutamol, 146 (86%) gave rapid boluses, 21 (12%) a longer loading dose and 164 (97%) an ongoing infusion, each with a range of doses and durations. Of 173 who used intravenous MgSO4, all used a bolus only. 41 (24%) used non-invasive ventilation. Conclusions: Signi ficant variation in ED consultant management of childhood wheeze exists despite the presence of national guidance. This reflects the lack of evidence in key areas of childhood wheeze and emphasises the need for further robust multicentre research studies

Ten years of major equestrian injury: are we addressing functional outcomes?

YesFunding provided by the Open Access Authors Fund

Determination of fungal activity in modified wood by means of micro-calorimetry and determination of total esterase activity

Beech and pine wood blocks were treated with 1,3-dimethylol-4,5-dihydroxyethylen urea (DMDHEU) to increasing weight percent gains (WPG). The resistance of the treated specimens against Trametes versicolor and Coniophora puteana, determined as mass loss, increased with increasing WPG of DMDHEU. Metabolic activity of the fungi in the wood blocks was assessed as total esterase activity (TEA) based on the hydrolysis of fluorescein diacetate and as heat or energy production determined by isothermal micro-calorimetry. Both methods revealed that the fungal activity was related with the WPG and the mass loss caused by the fungi. Still, fungal activity was detected even in wood blocks of the highest WPG and showed that the treatment was not toxic to the fungi. Energy production showed a higher consistency with the mass loss after decay than TEA; higher mass loss was more stringently reflected by higher heat production rate. Heat production did not proceed linearly, possibly due to the inhibition of fungal activity by an excess of carbon dioxide

Children’s rights online: challenges, dilemmas and emerging directions

In debates over internet governance, the interests of children figure unevenly, and only partial progress has been made in supporting children’s rights online globally. This chapter examines how the UN Convention on the Rights of the Child is helpful in mapping children’s rights to provision, protection and participation as they apply online as well as offline. However, challenges remain. First, opportunities and risks are positively linked, policy approaches are needed to resolve the potential conflict between protection on the one hand, and provision and participation on the other. Second, while parents may be relied on to some degree to balance their child’s rights and needs, the evidence suggests that a minority of parents are ill-equipped to manage this. Third, resolution is needed regarding the responsibility for implementing digital rights, since many governments prefer self-regulation in relation to internet governance. The chapter concludes by calling for a global governance body charged with ensuring the delivery of children’s rights